EGFR
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- Tucatinib hemiethanolate◐ .Made to order · 8–12 wks Item #: T649673View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- CCO.CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5.CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5
- Befotertinib◐ .Made to order · 8–12 wks Item #: B651968View ProductPricing & Pack Sizes
Technical Identifiers
- MC-Val-Cit-PAB-Amide-TLR7 agonist 4CAS: 2413016-49-4 Formula: C52H72N12O11 Molecular Weight: 1041.20◐ .Made to order · 8–12 wks Item #: M657028View ProductPricing & Pack Sizes
Technical Identifiers
- MS9427 TFAFormula: C50H59ClF4N8O14 Molecular Weight: 1107.5◐ .Made to order · 8–12 wks Item #: M658914View ProductPricing & Pack Sizes
Technical Identifiers
- JBJ-09-063 TFAFormula: C33H30F4N4O5S Molecular Weight: 670.67◐ .Made to order · 8–12 wks Item #: J659137View ProductPricing & Pack Sizes
Technical Identifiers
- PACAP-38 (31-38), human, mouse, rat TFAFormula: C49H84F3N17O13 Molecular Weight: 1176.29◐ .Made to order · 8–12 wks Item #: P659272View ProductPricing & Pack Sizes
Technical Identifiers
- BafisontamabCAS: 2437210-79-0◐ .Made to order · 8–12 wks Item #: B650069View ProductPricing & Pack Sizes
Technical Identifiers
- FIIN-3Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Made to order · 8–12 wks Item #: F650747View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]methyl]phenyl]prop-2-enamide
- SMILES
- CN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(CC4=CC=C(C=C4)NC(=O)C=C)C(=O)NC5=C(C(=CC(=C5Cl)OC)OC)Cl
- InChIKey
- SFLKJNSBBVSPFE-UHFFFAOYSA-N
- InChI
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- Nazartinib S-enantiomerCAS: 1508256-20-9 Formula: C26H31ClN6O2 Molecular Weight: 495.02◐ .Made to order · 8–12 wks Item #: N650927View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- O=C(C1=CC(C)=NC=C1)NC2=NC3=CC=CC(Cl)=C3N2[C@@H]4CN(C(/C=C/CN(C)C)=O)CCCC4
- Astragaloside VI◐ .Made to order · 8–12 wks Item #: A651074View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC1(C(CCC23C1C(CC4C2(C3)CCC5(C4(CC(C5C6(CCC(O6)C(C)(C)O)C)O)C)C)OC7C(C(C(C(O7)CO)O)O)O)OC8C(C(C(CO8)O)O)OC9C(C(C(C(O9)CO)O)O)O)C
- InChIKey
- FLPVEPQEIRRVKG-SXCMWBRFSA-N
- InChI
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- RTC-5Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: R651254View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-(trifluoromethoxy)benzenesulfonamide
- SMILES
- C1CC2=CC=CC=C2N(C3=C1C=CC(=C3)Cl)CCCNS(=O)(=O)C4=CC=C(C=C4)OC(F)(F)F
- InChIKey
- QYOJMNDDVVEPFN-UHFFFAOYSA-N
- InChI
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- Synonyms
- TRC-382 | N-(3-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-4-(trifluoromethoxy)benzenesulfonamide
- Gefitinib impurity 2◐ .Made to order · 8–12 wks Item #: G651932View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)benzamide
- SMILES
- COC1=C(C=C(C(=C1)N)C(=O)N)OCCCN2CCOCC2
- InChIKey
- HFUBNPPCNQAACT-UHFFFAOYSA-N
- InChI
- 1S/C15H23N3O4/c1-20-13-10-12(16)11(15(17)19)9-14(13)22-6-2-3-18-4-7-21-8-5-18/h9-10H,2-8,16H2,1H3,(H2,17,19)
- Synonyms
- Benzamide, 2-amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]- | Gefitinib impurity 2 | HY-100663 | I11734 | 2-Amino-4-me...
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Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.