Elastase

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  1. Sivelestat sodium tetrahydrate
    CAS: 201677-61-4 PubChem CID: 23663985 Formula: C20H21N2NaO7S.4H2O Molecular Weight: 528.51
    ● In Stock — US warehouse, ships to EU* Item #: S275861
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    IUPAC Name
    sodium;2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate;tetrahydrate
    SMILES
    CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].O.O.O.O.[Na+]
    InChIKey
    PLHREJBSQUSUCW-UHFFFAOYSA-M
    InChI
    1S/C20H22N2O7S.Na.4H2O/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24;;;;;/h4-11,22H,12H2,1-3H3,(H,21,25)(H,2show more
    Synonyms
    LY544349 Sodium Hydrate | LY-544349 SODIUM HYDRATE | Tox21_112570 | (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,...
  2. Alvelestat, Leukocyte elastase inhibitor
    CAS: 848141-11-7 Formula: C25H22F3N5O4S Molecular Weight: 545.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: A426223
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    IUPAC Name
    6-methyl-5-(2-methylpyrazol-3-yl)-N-[(5-methylsulfonylpyridin-2-yl)methyl]-2-oxo-1-[3-(trifluoromethyl)phenyl]pyridine-3-carboxamide
    SMILES
    CC1=C(C=C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)C(=O)NCC3=NC=C(C=C3)S(=O)(=O)C)C4=CC=NN4C
    InChIKey
    QNQZWEGMKJBHEM-UHFFFAOYSA-N
    InChI
    1S/C25H22F3N5O4S/c1-15-20(22-9-10-31-32(22)2)12-21(23(34)30-13-17-7-8-19(14-29-17)38(3,36)37)24(35)33(15)18-6-4-5-16(11-18)25(26,27)28/h4-12,14H,13H2,show more
    Synonyms
    NCGC00378593-07 | NSC60020 | 6-Methyl-5-(1-methyl-1H-pyrazol-5-yl)-N-{[5-(methylsulfonyl)pyridin-2-yl]methyl}-2-oxo-1...
  3. GW311616 hydrochloride
    CAS: 197890-44-1 PubChem CID: 9889108 Formula: C19H31N3O4S・HCl Molecular Weight: 434
    ◐ .Made to order · 8–12 wks Item #: G346619
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    IUPAC Name
    (3aR,6S,6aS)-4-methylsulfonyl-1-[(E)-4-piperidin-1-ylbut-2-enoyl]-6-propan-2-yl-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrol-5-one;hydrochloride
    SMILES
    CC(C)C1C2C(CCN2C(=O)C=CCN3CCCCC3)N(C1=O)S(=O)(=O)C.Cl
    InChIKey
    UFCZUKYPBPXODT-OFTZGUNKSA-N
    InChI
    1S/C19H31N3O4S.ClH/c1-14(2)17-18-15(22(19(17)24)27(3,25)26)9-13-21(18)16(23)8-7-12-20-10-5-4-6-11-20;/h7-8,14-15,17-18H,4-6,9-13H2,1-3H3;1H/b8-7+;/t15show more
    Synonyms
    AKOS030526696 | MS-27765 | Pyrrolo(3,2-b)pyrrol-2(1H)-one, hexahydro-3-(1-methylethyl)-1-(methylsulfonyl)-4-((2E)-1-o...
  4. JCP174
    CAS: 126062-19-9 Formula: C12H12ClNO3 Molecular Weight: 253.68
    ● In Stock — US warehouse, ships to EU* Item #: J412955
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    IUPAC Name
    7-amino-4-chloro-3-propoxyisochromen-1-one
    SMILES
    CCCOC1=C(C2=C(C=C(C=C2)N)C(=O)O1)Cl
    InChIKey
    MDOWUFTZOHGGHU-UHFFFAOYSA-N
    InChI
    1S/C12H12ClNO3/c1-2-5-16-12-10(13)8-4-3-7(14)6-9(8)11(15)17-12/h3-4,6H,2,5,14H2,1H3
  5. MeOSuc-AAPV-CMK
    CAS: 65144-34-5 Formula: C22H35ClN4O7 Molecular Weight: 502.99
    ● In Stock — US warehouse, ships to EU* Item #: S274813
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    IUPAC Name
    methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(3S)-1-chloro-4-methyl-2-oxopentan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]aminoshow more
    SMILES
    CC(C)C(C(=O)CCl)NC(=O)C1CCCN1C(=O)C(C)NC(=O)C(C)NC(=O)CCC(=O)OC
    InChIKey
    PJGDFLJMBAYGGC-XLPNERPQSA-N
    InChI
    1S/C22H35ClN4O7/c1-12(2)19(16(28)11-23)26-21(32)15-7-6-10-27(15)22(33)14(4)25-20(31)13(3)24-17(29)8-9-18(30)34-5/h12-15,19H,6-11H2,1-5H3,(H,24,29)(H,2show more
    Synonyms
    Elastase Inhibitor III | N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone | N-(Methoxysuccinyl)-L-alanyl-L-ala...
  6. Sivelestat sodium tetrahydrate
    CAS: 201677-61-4 PubChem CID: 23663985 Formula: C20H21N2NaO7S.4H2O Molecular Weight: 528.51
    10mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: S422452
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    sodium;2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate;tetrahydrate
    SMILES
    CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)[O-].O.O.O.O.[Na+]
    InChIKey
    PLHREJBSQUSUCW-UHFFFAOYSA-M
    InChI
    1S/C20H22N2O7S.Na.4H2O/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24;;;;;/h4-11,22H,12H2,1-3H3,(H,21,25)(H,2show more
    Synonyms
    Sivelestat sodium|201677-61-4|Sivelestat sodium tetrahydrate|sivelestat sodium hydrate|Elaspol|ONO-5046.Na|LY544349 S...
  7. Sivelestat sodium salt hydrate, Leukocyte elastase inhibitor
    CAS: 127373-66-4 EC Number: 695-701-7 Formula: C20H22N2O7S Molecular Weight: 434.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: S421126
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    Technical Identifiers
    IUPAC Name
    2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetic acid
    SMILES
    CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)O
    InChIKey
    BTGNGJJLZOIYID-UHFFFAOYSA-N
    InChI
    1S/C20H22N2O7S/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24)
    Synonyms
    dl-N-Acetylhomocysteinethiolactone | ONO5046;LY544349;EI546 | SIVELESTAT [INN] | SIVELESTAT [MART.] | 2,2-Dimethyl-pr...
  8. 23-Hydroxytormentic acid
    CAS: 70868-78-9 Formula: C30H48O6 Molecular Weight: 504.7
    ◐ .Made to order · 8–12 wks Item #: H463877
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    Technical Identifiers
    IUPAC Name
    (1R,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-1,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tshow more
    SMILES
    CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1(C)O)C)C(=O)O
    InChIKey
    YCOKATFNRPZIIU-NIZSJLHKSA-N
    InChI
    1S/C30H48O6/c1-17-9-12-30(24(34)35)14-13-27(4)18(22(30)29(17,6)36)7-8-21-25(2)15-19(32)23(33)26(3,16-31)20(25)10-11-28(21,27)5/h7,17,19-23,31-33,36H,8show more
    Synonyms
    Q27136389 | HY-N8164 | (2alpha,3beta)-2,3,19,23-tetrahydroxyurs-12-en-28-oic acid | 19 | 19 alpha-Hydroxyasiatic acid...
  9. lonodelestat
    CAS: 906547-89-5 PubChem CID: 71532754
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: L611566
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    Technical Identifiers
    SMILES
    NCCCC[C@@H]1NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NCshow more
    InChIKey
    JMWYNUHGKFJVIB-QGFXQWJDSA-N
    InChI
    1S/C71H111N15O19/c1-6-8-9-10-11-12-19-46-60(94)76-48(30-32-56(91)92)63(97)82-58(42(5)88)67(101)74-41(4)59(93)80-50(39-87)64(98)81-57(40(3)7-2)71(105)8show more
    Synonyms
    cyclo[Ala-Ser-Ile-Pro-Pro-Gln-Lys-Tyr-D-Pro-Pro-Nle(Bu)-Glu-Thr] | 1,13-Anhydro(L-alanyl-L-seryl-L-isoleucyl-L-prolyl...
  10. Secologanoside
    CAS: 59472-23-0 Formula: C16H22O11 Molecular Weight: 390.34
    ◐ .Made to order · 8–12 wks Item #: S646529
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    Technical Identifiers
    SMILES
    C=C[C@H]([C@@H](C(C(O)=O)=CO1)CC(O)=O)[C@]1([H])O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO
  11. Chrysophanol 8-O-glucoside
    CAS: 13241-28-6 EC Number: 111-885-9 PubChem CID: 442731 Formula: C21H20O9 Molecular Weight: 416.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: C649519
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    IUPAC Name
    1-hydroxy-3-methyl-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione
    SMILES
    CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=CC=C3OC4C(C(C(C(O4)CO)O)O)O
    InChIKey
    WMMOMSNMMDMSRB-JNHRPPPUSA-N
    InChI
    1S/C21H20O9/c1-8-5-10-14(11(23)6-8)18(26)15-9(16(10)24)3-2-4-12(15)29-21-20(28)19(27)17(25)13(7-22)30-21/h2-6,13,17,19-23,25,27-28H,7H2,1H3/t13-,17-,1show more
    Synonyms
    CHRYSOPHANOL-8-MONO-.BETA.-D-GLUCOSIDE | LMPK13040007 | GLUCOPYRANOSIDE, 8-HYDROXY-6-METHYL-1-ANTHRAQUINONYL, .BETA.-...
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Frequently Asked Questions

Which compounds are listed for Elastase?
Compounds associated with Elastase are grouped here under the Metabolic Enzyme/Protease classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does Elastase sit within Metabolic Enzyme/Protease?
Elastase is one target listing within the Metabolic Enzyme/Protease classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from Elastase?
For compounds listed under Elastase, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for Elastase?
Browse the parent Metabolic Enzyme/Protease listing to reach targets neighbouring Elastase, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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