Elastase

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  1. DMP 777
    CAS: 157341-41-8 PubChem CID: 177992 Formula: C31H40N4O6 Molecular Weight: 564.69
    ◐ .Made to order · 8–12 wks Item #: D649587
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    IUPAC Name
    (2S)-N-[(1R)-1-(1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-(4-methylpiperazine-1-carbonyl)phenoxy]-4-oxoazetidine-1-carboxamide
    SMILES
    CCCC(C1=CC2=C(C=C1)OCO2)NC(=O)N3C(C(C3=O)(CC)CC)OC4=CC=C(C=C4)C(=O)N5CCN(CC5)C
    InChIKey
    ZSDCIRYNTCVTMF-GIGWZHCTSA-N
    InChI
    1S/C31H40N4O6/c1-5-8-24(22-11-14-25-26(19-22)40-20-39-25)32-30(38)35-28(37)31(6-2,7-3)29(35)41-23-12-9-21(10-13-23)27(36)34-17-15-33(4)16-18-34/h9-14,show more
    Synonyms
    (2S)-N-[(1R)-1-(1,3-benzodioxol-5-yl)butyl]-3,3-diethyl-2-[4-(4-methylpiperazine-1-carbonyl)phenoxy]-4-oxoazetidine-1...
  2. FK706
    CAS: 144055-55-0 PubChem CID: 23690296 Formula: C26H32F3N4NaO7 Molecular Weight: 592.54
    ◐ .Made to order · 8–12 wks Item #: F651524
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    IUPAC Name
    sodium;2-[[4-[[(2S)-3-methyl-1-oxo-1-[(2S)-2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)carbamoyl]pyrrolidin-1-yl]butan-2-yl]carbamoyl]benzoyl]amino]show more
    SMILES
    CC(C)C(C(=O)C(F)(F)F)NC(=O)C1CCCN1C(=O)C(C(C)C)NC(=O)C2=CC=C(C=C2)C(=O)NCC(=O)[O-].[Na+]
    InChIKey
    DNTYCMNNMGACPR-JSAITXCESA-M
    InChI
    1S/C26H33F3N4O7.Na/c1-13(2)19(21(36)26(27,28)29)31-24(39)17-6-5-11-33(17)25(40)20(14(3)4)32-23(38)16-9-7-15(8-10-16)22(37)30-12-18(34)35;/h7-10,13-14,show more
  3. AE-3763
    CAS: 291778-77-3 PubChem CID: 9807572 Formula: C23H34F3N5O7 Molecular Weight: 549.54
    ◐ .Made to order · 8–12 wks Item #: A651980
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    IUPAC Name
    2-[3-[2-[[(2S)-3-methyl-1-oxo-1-[(2S)-2-[[(3S)-1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl]carbamoyl]pyrrolidin-1-yl]butan-2-yl]amino]-2-oxoethyl]-2-oxoshow more
    SMILES
    CC(C)C(C(=O)C(F)(F)F)NC(=O)C1CCCN1C(=O)C(C(C)C)NC(=O)CN2CCN(C2=O)CC(=O)O
    InChIKey
    DHQQXRRWRZFGDW-WBAXXEDZSA-N
    InChI
    1S/C23H34F3N5O7/c1-12(2)17(19(35)23(24,25)26)28-20(36)14-6-5-7-31(14)21(37)18(13(3)4)27-15(32)10-29-8-9-30(22(29)38)11-16(33)34/h12-14,17-18H,5-11H2,1show more
    Synonyms
    tripeptide-based inhibitor, 14v | SCHEMBL6588149 | DHQQXRRWRZFGDW-WBAXXEDZSA-N | F7YC3C4YFS | AE3763 | AE-3763 | 2-(3...
  4. GW311616
    CAS: 198062-54-3 PubChem CID: 9800961 Formula: C19H31N3O4S Molecular Weight: 397.53
    ◐ .Made to order · 8–12 wks Item #: G647148
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    IUPAC Name
    (3aR,6S,6aS)-4-methylsulfonyl-1-[(E)-4-piperidin-1-ylbut-2-enoyl]-6-propan-2-yl-3,3a,6,6a-tetrahydro-2H-pyrrolo[3,2-b]pyrrol-5-one
    SMILES
    CC(C)C1C2C(CCN2C(=O)C=CCN3CCCCC3)N(C1=O)S(=O)(=O)C
    InChIKey
    NDNKNUMSTIMSHQ-URZKGLGPSA-N
    InChI
    1S/C19H31N3O4S/c1-14(2)17-18-15(22(19(17)24)27(3,25)26)9-13-21(18)16(23)8-7-12-20-10-5-4-6-11-20/h7-8,14-15,17-18H,4-6,9-13H2,1-3H3/b8-7+/t15-,17+,18-show more
    Synonyms
    GW 311616 | L8012V52PN | MS-26715 | PYRROLO(3,2-B)PYRROL-2(1H)-ONE, HEXAHYDRO-3-(1-METHYLETHYL)-1-(METHYLSULFONYL)-4-...
  5. Lodelaben
    CAS: 111149-90-7 PubChem CID: 56557 Formula: C25H41ClO3 Molecular Weight: 425.04
    ◐ .Made to order · 8–12 wks Item #: L649654
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    IUPAC Name
    2-chloro-4-(1-hydroxyoctadecyl)benzoic acid
    SMILES
    CCCCCCCCCCCCCCCCCC(C1=CC(=C(C=C1)C(=O)O)Cl)O
    InChIKey
    SYCYJNHKNPPDAT-UHFFFAOYSA-N
    InChI
    1S/C25H41ClO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(27)21-18-19-22(25(28)29)23(26)20-21/h18-20,24,27H,2-17H2,1H3,(H,28,29)
    Synonyms
    AKOS040733610 | Q27261182 | BENZOIC ACID, 2-CHLORO-4-(1-HYDROXYOCTADECYL)-, (+/-)- | HY-100240 | LODELABEN [USAN] | B...
  6. ZD-0892
    CAS: 171964-73-1 PubChem CID: 9892148 Formula: C24H32F3N3O5 Molecular Weight: 499.52
    ◐ .Made to order · 8–12 wks Item #: Z650388
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    Technical Identifiers
    IUPAC Name
    (2S)-1-[(2S)-2-[(4-methoxybenzoyl)amino]-3-methylbutanoyl]-N-[(3S)-1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl]pyrrolidine-2-carboxamide
    SMILES
    CC(C)C(C(=O)C(F)(F)F)NC(=O)C1CCCN1C(=O)C(C(C)C)NC(=O)C2=CC=C(C=C2)OC
    InChIKey
    PNILZVBINXNWHW-FHWLQOOXSA-N
    InChI
    1S/C24H32F3N3O5/c1-13(2)18(20(31)24(25,26)27)28-22(33)17-7-6-12-30(17)23(34)19(14(3)4)29-21(32)15-8-10-16(35-5)11-9-15/h8-11,13-14,17-19H,6-7,12H2,1-5show more
    Synonyms
    (S)-1-[(S)-2-(4-Methoxy-benzoylamino)-3-methyl-butyryl]-pyrrolidine-2-carboxylic acid ((S)-3,3,3-trifluoro-1-isopropy...
  7. BAY-85-8501
    CAS: 1161921-82-9 PubChem CID: 66601502 Formula: C22H17F3N4O3S Molecular Weight: 474.46
    ◐ .Made to order · 8–12 wks Item #: B651395
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    Technical Identifiers
    IUPAC Name
    (4S)-4-(4-cyano-2-methylsulfonylphenyl)-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4H-pyrimidine-5-carbonitrile
    SMILES
    CC1=C(C(N(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)C)C3=C(C=C(C=C3)C#N)S(=O)(=O)C)C#N
    InChIKey
    YAJWYFPMASPAMM-HXUWFJFHSA-N
    InChI
    1S/C22H17F3N4O3S/c1-13-18(12-27)20(17-8-7-14(11-26)9-19(17)33(3,31)32)28(2)21(30)29(13)16-6-4-5-15(10-16)22(23,24)25/h4-10,20H,1-3H3/t20-/m1/s1
    Synonyms
    AKOS040736087 | BAY 85-8501 | SCHEMBL121431 | (4S)-4-(4-cyano-2-methylsulfonylphenyl)-3,6-dimethyl-2-oxo-1-[3-(triflu...
  8. 2-(Chloromethyl)-1,1-dioxo-1,2-benzothiazol-3-one
    CAS: 13947-21-2 EC Number: 961-055-2 PubChem CID: 2302435 Formula: C8H6ClNO3S Molecular Weight: 231.66
    ◐ .Made to order · 8–12 wks Item #: C668689
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    IUPAC Name
    2-(chloromethyl)-1,1-dioxo-1,2-benzothiazol-3-one
    SMILES
    C1=CC=C2C(=C1)C(=O)N(S2(=O)=O)CCl
    InChIKey
    RFAHYFCQZDZXLP-UHFFFAOYSA-N
    InChI
    1S/C8H6ClNO3S/c9-5-10-8(11)6-3-1-2-4-7(6)14(10,12)13/h1-4H,5H2
    Synonyms
    2-Chloromethyl-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one | 2-(chloromethyl)-1,1-dioxo-1,2-benzothiazo...
  9. Skullcapflavone I
    CAS: 41060-16-6 PubChem CID: 5320399 Formula: C17H14O6 Molecular Weight: 314.29
    ◐ .Made to order · 8–12 wks Item #: S709643
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    IUPAC Name
    5-hydroxy-2-(2-hydroxyphenyl)-7,8-dimethoxychromen-4-one
    SMILES
    COC1=C(C2=C(C(=C1)O)C(=O)C=C(O2)C3=CC=CC=C3O)OC
    InChIKey
    CZRGNFVQUYWGKP-UHFFFAOYSA-N
    InChI
    1S/C17H14O6/c1-21-14-8-12(20)15-11(19)7-13(23-17(15)16(14)22-2)9-5-3-4-6-10(9)18/h3-8,18,20H,1-2H3
  10. 1-(3-Methylbenzoyl)-1H-indazole-3-carbonitrile
    CAS: 1448314-31-5 PubChem CID: 71818549
    ◐ .Made to order · 8–12 wks Item #: M987506
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    Technical Identifiers
    IUPAC Name
    1-(3-methylbenzoyl)indazole-3-carbonitrile
    SMILES
    CC1=CC(=CC=C1)C(=O)N2C3=CC=CC=C3C(=N2)C#N
    InChIKey
    KRFSMLDUZFVINX-UHFFFAOYSA-N
    InChI
    1S/C16H11N3O/c1-11-5-4-6-12(9-11)16(20)19-15-8-3-2-7-13(15)14(10-17)18-19/h2-9H,1H3
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Frequently Asked Questions

Which compounds are listed for Elastase?
Compounds associated with Elastase are grouped here under the Metabolic Enzyme/Protease classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does Elastase sit within Metabolic Enzyme/Protease?
Elastase is one target listing within the Metabolic Enzyme/Protease classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from Elastase?
For compounds listed under Elastase, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for Elastase?
Browse the parent Metabolic Enzyme/Protease listing to reach targets neighbouring Elastase, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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