LRRK2
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57 products
Popular Products
- MLi-2, Inhibitor of leucine rich repeat kinase 2CAS: 1627091-47-7 Formula: C21H25N5O2 Molecular Weight: 379.46Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: M276039View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2R,6S)-2,6-dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1H-indazol-3-yl]pyrimidin-4-yl]morpholine
- SMILES
- CC1CN(CC(O1)C)C2=NC=NC(=C2)C3=NNC4=C3C=C(C=C4)OC5(CC5)C
- InChIKey
- ATUUNJCZCOMUKD-OKILXGFUSA-N
- InChI
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- Synonyms
- (2R,6S)-2,6-Dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1H-indazol-3-yl]pyrimidin-4-yl]morpholine | cis-2,6-Dimethyl-4-...
- Indazole● In Stock — US warehouse, ships to EU* Item #: I157585View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1H-indazole
- SMILES
- C1=CC=C2C(=C1)C=NN2
- InChIKey
- BAXOFTOLAUCFNW-UHFFFAOYSA-N
- InChI
- 1S/C7H6N2/c1-2-4-7-6(3-1)5-8-9-7/h1-5H,(H,8,9)
- Synonyms
- 1,2-Benzopyrazole | F0918-7060 | F1918-0009 | Indazole, 6 | UNII-7C4VQE5C03 | 1H-indazol | EINECS 205-978-4 | FT-0627...
- IKK-16 (hydrochloride)CAS: 1186195-62-9 Formula: C28H29N5OS • HCl Molecular Weight: 520.09● In Stock — US warehouse, ships to EU* Item #: I274699View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [4-[[4-(1-benzothiophen-2-yl)pyrimidin-2-yl]amino]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone;hydrochloride
- SMILES
- C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5.Cl
- InChIKey
- XFVDIVQCZWDBCW-UHFFFAOYSA-N
- InChI
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- Synonyms
- N-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamidehydrochloride
- IKK-16 (IKK Inhibitor VII)● In Stock — US warehouse, ships to EU* Item #: I129698View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [4-[[4-(1-benzothiophen-2-yl)pyrimidin-2-yl]amino]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone
- SMILES
- C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5
- InChIKey
- BWZJBXAPRCVCKQ-UHFFFAOYSA-N
- InChI
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- Synonyms
- (4-((4-(1-Benzothiophen-2-yl)pyrimidin-2-yl)amino)phenyl)(4-pyrrolidin-1-ylpiperidin-1-yl)methanone | 873225-46-8 (fr...
- GNE7915, Inhibitor of leucine rich repeat kinase 2;Inhibitor of TTK protein kinaseCAS: 1351761-44-8 Formula: C19H21F4N5O3 Molecular Weight: 443.4Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G275946View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [4-[[4-(ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-fluoro-5-methoxyphenyl]-morpholin-4-ylmethanone
- SMILES
- CCNC1=NC(=NC=C1C(F)(F)F)NC2=C(C=C(C(=C2)F)C(=O)N3CCOCC3)OC
- InChIKey
- XCFLWTZSJYBCPF-UHFFFAOYSA-N
- InChI
- 1S/C19H21F4N5O3/c1-3-24-16-12(19(21,22)23)10-25-18(27-16)26-14-9-13(20)11(8-15(14)30-2)17(29)28-4-6-31-7-5-28/h8-10H,3-7H2,1-2H3,(H2,24,25,26,27)
- Synonyms
- [4-[[4-(Ethylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro-5-methoxyphenyl]-4-morpholinyl-methanone | (4-(...
- GSK2578215ACAS: 1285515-21-0 Formula: C24H18FN3O2 Molecular Weight: 399.42● In Stock — US warehouse, ships to EU* Item #: G166851View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-(2-fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide
- SMILES
- C1=CC=C(C=C1)COC2=C(C=C(C=C2)C3=CC(=NC=C3)F)C(=O)NC4=CN=CC=C4
- InChIKey
- WCIGMFCFPXZRMQ-UHFFFAOYSA-N
- InChI
- 1S/C24H18FN3O2/c25-23-14-19(10-12-27-23)18-8-9-22(30-16-17-5-2-1-3-6-17)21(13-18)24(29)28-20-7-4-11-26-15-20/h1-15H,16H2,(H,28,29)
- Synonyms
- 5-(2-fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide | Benzamide, 5-(2-fluoro-4-pyridinyl)-2-(phenylmetho...
- JH-II-127CAS: 1700693-08-8 Formula: C19H21ClN6O3 Molecular Weight: 416.87● In Stock — US warehouse, ships to EU* Item #: J275343View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [4-[[5-chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-morpholin-4-ylmethanone
- SMILES
- CNC1=NC(=NC2=C1C(=CN2)Cl)NC3=C(C=C(C=C3)C(=O)N4CCOCC4)OC
- InChIKey
- HUEKBQXFNHWTQQ-UHFFFAOYSA-N
- InChI
- 1S/C19H21ClN6O3/c1-21-16-15-12(20)10-22-17(15)25-19(24-16)23-13-4-3-11(9-14(13)28-2)18(27)26-5-7-29-8-6-26/h3-4,9-10H,5-8H2,1-2H3,(H3,21,22,23,24,25)
- Synonyms
- [4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-morpholin-4-ylmethanone | [4-[[...
- LRRK2-IN-1, Inhibitor of leucine rich repeat kinase 2CAS: 1234480-84-2 Formula: C31H38N8O3 Molecular Weight: 570.7Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: L125224View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one
- SMILES
- CN1CCN(CC1)C2CCN(CC2)C(=O)C3=CC(=C(C=C3)NC4=NC=C5C(=N4)N(C6=CC=CC=C6C(=O)N5C)C)OC
- InChIKey
- IWMCPJZTADUIFX-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- BRD-K01436366-001-01-6 | 2,6-Diamino-hexanoic acid; hydrochloride | BDBM50379529 | 2-((2-Methoxy-4-(4-(4-methylpipera...
- CZC 2514610mM in DMSO● In Stock — US warehouse, ships to EU* Item #: C420850View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[[5-fluoro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide
- SMILES
- COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)F
- InChIKey
- XXHHOTZUJIXPJX-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide；CZC-25146；...
- CZC 25146● In Stock — US warehouse, ships to EU* Item #: C287537View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[[5-fluoro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide
- SMILES
- COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)F
- InChIKey
- XXHHOTZUJIXPJX-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide | CZC-2514...
- CZC 54252 hydrochloride● In Stock — US warehouse, ships to EU* Item #: C288538View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[[5-chloro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide;hydrochloride
- SMILES
- COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)Cl.Cl
- InChIKey
- KWCBHUPLQMUKAF-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochlor...
- CZC-25146 hydrochloride● In Stock — US warehouse, ships to EU* Item #: C412508View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[[5-fluoro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide;hydrochloride
- SMILES
- COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)F.Cl
- InChIKey
- SKYQTYQDKAOHLP-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- CZC-25146(hydrochloride) | 1330003-04-7 | N-[2-[[5-fluoro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]p...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
Which compounds are listed for LRRK2?
Compounds associated with LRRK2 are grouped here under the Autophagy classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does LRRK2 sit within Autophagy?
LRRK2 is one target listing within the Autophagy classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from LRRK2?
For compounds listed under LRRK2, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for LRRK2?
Browse the parent Autophagy listing to reach targets neighbouring LRRK2, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.