Mixed Lineage Kinase
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23 products
Popular Products
- NecrosulfonamideCAS: 1360614-48-7 Formula: C18H15N5O6S2 Molecular Weight: 461.47● In Stock — US warehouse, ships to EU* Item #: N302487View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-[4-[(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophen-2-yl)prop-2-enamide
- SMILES
- COC1=NC=CN=C1NS(=O)(=O)C2=CC=C(C=C2)NC(=O)C=CC3=CC=C(S3)[N+](=O)[O-]
- InChIKey
- FNPPHVLYVGMZMZ-XBXARRHUSA-N
- InChI
- 1S/C18H15N5O6S2/c1-29-18-17(19-10-11-20-18)22-31(27,28)14-6-2-12(3-7-14)21-15(24)8-4-13-5-9-16(30-13)23(25)26/h2-11H,1H3,(H,19,22)(H,21,24)/b8-4+
- Synonyms
- STL429797 | HY-100573A | SCHEMBL17509590 | DTXSID00364437 | MFCD02370191 | (E)-N-[4-[N-(3-methoxypyrazin-2-yl)sulfamo...
- (E/Z)-NecrosulfonamideCAS: 432531-71-0 Formula: C18H15N5O6S2 Molecular Weight: 461.47Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: N276059View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-[4-[(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophen-2-yl)prop-2-enamide
- SMILES
- COC1=NC=CN=C1NS(=O)(=O)C2=CC=C(C=C2)NC(=O)C=CC3=CC=C(S3)[N+](=O)[O-]
- InChIKey
- FNPPHVLYVGMZMZ-XBXARRHUSA-N
- InChI
- 1S/C18H15N5O6S2/c1-29-18-17(19-10-11-20-18)22-31(27,28)14-6-2-12(3-7-14)21-15(24)8-4-13-5-9-16(30-13)23(25)26/h2-11H,1H3,(H,19,22)(H,21,24)/b8-4+
- Synonyms
- STL429797 | HY-100573A | SCHEMBL17509590 | DTXSID00364437 | MFCD02370191 | (E)-N-[4-[N-(3-methoxypyrazin-2-yl)sulfamo...
- URMC-099, Inhibitor of cyclin dependent kinase like 2;Inhibitor of death associated protein kinase 3;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of leucine rich repeat kinase 2;Inhibitor of mitogen-activated protein kinase kinase kinase 10;InhibitMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%● In Stock — US warehouse, ships to EU* Item #: U275952View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-(1H-indol-5-yl)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine
- SMILES
- CN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(NC=C4C5=CC6=C(C=C5)NC=C6)N=C3
- InChIKey
- QKKIWEILHCXECO-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 3-(1H-Indol-5-yl)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-1Hpyrrolo[2,3-b]pyridine
- PRT062607 (P505-15, BIIB057) HCl● In Stock — US warehouse, ships to EU* Item #: P129908View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[3-(triazol-2-yl)anilino]pyrimidine-5-carboxamide;hydrochloride
- SMILES
- C1CCC(C(C1)N)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)N4N=CC=N4)C(=O)N.Cl
- InChIKey
- RMNLLPXCNDZJMJ-IDVLALEDSA-N
- InChI
- show more
- Synonyms
- PRT062607 Hydrochloride | 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5...
- CEP 1347, Inhibitor of mitogen-activated protein kinase kinase kinase 10;Inhibitor of mitogen-activated protein kinase kinase kinase 11;Inhibitor of mitogen-activated protein kinase kinase kinase 12;Inhibitor of mitogen-activated protein kinase kinase kinase 9CAS: 156177-65-0 Formula: C33H33N3O5S2 Molecular Weight: 615.76Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%(HPLC)◐ .Made to order · 8–12 wks Item #: C287932View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CCSCC1=CC2=C(C=C1)N3C4CC(C(O4)(N5C6=C(C=C(C=C6)CSCC)C7=C8CNC(=O)C8=C2C3=C75)C)(C(=O)OC)O
- InChIKey
- SCMLRESZJCKCTC-KMYQRJGFSA-N
- InChI
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- Synonyms
- (9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,...
- URMC-099, Inhibitor of cyclin dependent kinase like 2;Inhibitor of death associated protein kinase 3;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of leucine rich repeat kinase 2;Inhibitor of mitogen-activated protein kinase kinase kinase 10;InhibitMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: U420995View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-(1H-indol-5-yl)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine
- SMILES
- CN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(NC=C4C5=CC6=C(C=C5)NC=C6)N=C3
- InChIKey
- QKKIWEILHCXECO-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 3-(1H-Indol-5-yl)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-1Hpyrrolo[2,3-b]pyridine
- TC13172Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: T646263View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[3-(3-hydroxyphenyl)prop-2-ynyl]-1,7-dimethyl-8-methylsulfonylpurine-2,6-dione
- SMILES
- CN1C2=C(N=C1S(=O)(=O)C)N(C(=O)N(C2=O)C)CC#CC3=CC(=CC=C3)O
- InChIKey
- ZTQLCNOQWGSELY-UHFFFAOYSA-N
- InChI
- 1S/C17H16N4O5S/c1-19-13-14(18-16(19)27(3,25)26)21(17(24)20(2)15(13)23)9-5-7-11-6-4-8-12(22)10-11/h4,6,8,10,22H,9H2,1-3H3
- Synonyms
- 3-(3-(3-Hydroxyphenyl)prop-2-yn-1-yl)-1,7-dimethyl-8-(methylsulfonyl)-3,7-dihydro-1H-purine-2,6-dione | ZB1558 | 3-[3...
- KWCN-41CAS: 2913223-17-1 Formula: C18H17N3O2 Molecular Weight: 307.35◐ .Made to order · 8–12 wks Item #: K651019View ProductPricing & Pack Sizes
Technical Identifiers
- RIP1/RIP3/MLKL activator 1CAS: 2682850-41-3 Formula: C43H56N4O3 Molecular Weight: 676.93◐ .Made to order · 8–12 wks Item #: R651898View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- CC1=C(C(C=C2C1=CC=C3[C@]4(CC[C@]5(CC[C@@](C(NCC6=CN(N=N6)CC7=CC=C(C=C7)C(C)(C)C)=O)(CC5[C@@]4(CC[C@@]23C)C)C)C)C)=O)O
- NecroIr1Formula: C40H29ClIrN5O- Molecular Weight: 823.36◐ .Made to order · 8–12 wks Item #: N658924View ProductPricing & Pack Sizes
Technical Identifiers
- GW806742X hydrochlorideFormula: C25H23ClF3N7O4S Molecular Weight: 610.01◐ .Made to order · 8–12 wks Item #: G659343View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- [H]Cl.O=S(C1=CC=CC(NC2=NC=CC(N(C)C3=CC=C(NC(NC4=CC=C(OC(F)(F)F)C=C4)=O)C=C3)=N2)=C1)(N)=O
- Necrosulfonamide-d4CAS: 1795144-22-7 Formula: C18H11D4N5O6S2 Molecular Weight: 465.5◐ .Made to order · 8–12 wks Item #: N649885View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-3-(5-nitrothiophen-2-yl)-N-[2,3,5,6-tetradeuterio-4-[(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]prop-2-enamide
- SMILES
- COC1=NC=CN=C1NS(=O)(=O)C2=CC=C(C=C2)NC(=O)C=CC3=CC=C(S3)[N+](=O)[O-]
- InChIKey
- FNPPHVLYVGMZMZ-GTQWLDGCSA-N
- InChI
- show more
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the Mixed Lineage Kinase listing put together?
It draws on reported Mixed Lineage Kinase annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Mixed Lineage Kinase modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Mixed Lineage Kinase entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Mixed Lineage Kinase compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Mixed Lineage Kinase work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Mixed Lineage Kinase compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Mixed Lineage Kinase compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.