Necroptosis
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104 products
Popular Products
- Necrostatin-5CAS: 337349-54-9 Formula: C19H17N3O2S2 Molecular Weight: 383.49● In Stock — US warehouse, ships to EU* Item #: N274792View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[[3-(4-methoxyphenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetonitrile
- SMILES
- COC1=CC=C(C=C1)N2C(=O)C3=C(N=C2SCC#N)SC4=C3CCCC4
- InChIKey
- VGONMECBFMCKBS-UHFFFAOYSA-N
- InChI
- 1S/C19H17N3O2S2/c1-24-13-8-6-12(7-9-13)22-18(23)16-14-4-2-3-5-15(14)26-17(16)21-19(22)25-11-10-20/h6-9H,2-5,11H2,1H3
- Synonyms
- STL304760 | SCHEMBL12682848 | Necrostatin-5, >=98% (HPLC), solid | AKOS000510375 | Oprea1_213608 | Oprea1_435788 | HM...
- Necrostatin-1CAS: 64419-92-7 Formula: C12H11N3OS Molecular Weight: 245.3◐ .Made to order · 8–12 wks Item #: N276209View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-(1H-indol-3-ylmethyl)-2-sulfanylideneimidazolidin-4-one
- SMILES
- C1=CC=C2C(=C1)C(=CN2)CC3C(=O)NC(=S)N3
- InChIKey
- MPLRRPKKFHUEEL-UHFFFAOYSA-N
- InChI
- 1S/C12H11N3OS/c16-11-10(14-12(17)15-11)5-7-6-13-9-4-2-1-3-8(7)9/h1-4,6,10,13H,5H2,(H2,14,15,16,17)
- Synonyms
- 5-(Indole-3-yl)methyl-2-thioxo-imidazolidin-4-one | Nec-1i | 5-(1H-Indol-3-ylmethyl)-2-thioxo-imidazolidin-4-one | 5-...
- Necrostatin-7◐ .Made to order · 8–12 wks Item #: N274719View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (5Z)-5-[[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one
- SMILES
- C1=CC(=CC=C1C2=C(C=NN2)C=C3C(=O)N(C(=N)S3)C4=NC=CS4)F
- InChIKey
- SMJGLNVGTJLIRV-KBEFMPHXSA-N
- InChI
- 1S/C16H10FN5OS2/c17-11-3-1-9(2-4-11)13-10(8-20-21-13)7-12-14(23)22(15(18)25-12)16-19-5-6-24-16/h1-8,18H,(H,20,21)/b12-7-,18-15?
- Synonyms
- SMJGLNVGTJLIRV-KBEFMPHXSA-N | (5Z)-5-[[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2-imino-3-(1,3-thiazol-2-yl)-1...
- Cholesteryl hemisuccinate(CHEMS)Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: C132483View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC(=O)CCC(=O)O)C)C
- InChIKey
- WLNARFZDISHUGS-MIXBDBMTSA-N
- InChI
- show more
- Synonyms
- DTXSID10934145 | T3J4KS4201 | Cholesteryl hydrogen succinate | Cholesterol Hydrogen Succinate | E10155 | 3-(3-CHOLEST...
- Sodium CyclamateCAS: 139-05-9 EC Number: 205-348-9 PubChem CID: 23665706 Formula: C6H12NNaO3S Molecular Weight: 201.22● In Stock — Germany Item #: S109886View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- sodium;N-cyclohexylsulfamate
- SMILES
- C1CCC(CC1)NS(=O)(=O)[O-].[Na+]
- InChIKey
- UDIPTWFVPPPURJ-UHFFFAOYSA-M
- InChI
- 1S/C6H13NO3S.Na/c8-11(9,10)7-6-4-2-1-3-5-6;/h6-7H,1-5H2,(H,8,9,10);/q;+1/p-1
- Synonyms
- Assurgrin vollsuss | Cyclamate de sodium [INN-French] | Natriumzyklamate [German] | UDIPTWFVPPPURJ-UHFFFAOYSA-M | DB0...
- Thioacetamide(TAA)Solid ≥98%● In Stock — Germany Item #: T104039View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- ethanethioamide
- SMILES
- CC(=S)N
- InChIKey
- YUKQRDCYNOVPGJ-UHFFFAOYSA-N
- InChI
- 1S/C2H5NS/c1-2(3)4/h1H3,(H2,3,4)
- Synonyms
- CH3CSNH2 | F0001-1649 | EC 200-541-4 | Ethanimidothioic acid | Tox21_301295 | Acetothioamide | EN300-19496 | Thioacet...
- Thioacetamide(TAA)Solid ACS ? ACS grade — meets American Chemical Society specifications, the analytical benchmark in the US. Use for analytical and QC work needing ACS-defined purity. ≥99%● In Stock — Germany Item #: T118452View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- ethanethioamide
- SMILES
- CC(=S)N
- InChIKey
- YUKQRDCYNOVPGJ-UHFFFAOYSA-N
- InChI
- 1S/C2H5NS/c1-2(3)4/h1H3,(H2,3,4)
- Synonyms
- CH3CSNH2 | F0001-1649 | EC 200-541-4 | Ethanimidothioic acid | Tox21_301295 | Acetothioamide | EN300-19496 | Thioacet...
- N-(Phosphonomethyl)glycine● In Stock — US warehouse, ships to EU* Item #: P123117View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-(phosphonomethylamino)acetic acid
- SMILES
- C(C(=O)O)NCP(=O)(O)O
- InChIKey
- XDDAORKBJWWYJS-UHFFFAOYSA-N
- InChI
- 1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)
- Synonyms
- glyphosate | N-(Phosphonomethyl) Glycine | Safal | Gliz | Hockey | Roundup | Sonic | Caswell No. 661A | Glifoglex | G...
- Cyclamic acid, Antagonist of TAS2R31;Antagonist of TAS2R43Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: C129435View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- cyclohexylsulfamic acid
- SMILES
- C1CCC(CC1)NS(=O)(=O)O
- InChIKey
- HCAJEUSONLESMK-UHFFFAOYSA-N
- InChI
- 1S/C6H13NO3S/c8-11(9,10)7-6-4-2-1-3-5-6/h6-7H,1-5H2,(H,8,9,10)
- Synonyms
- E78799 | Cyclamic acid (USAN) | Cyclohexylamide sulfate | s4015 | Cyclamsaeure | HMS3264K03 | Cyclohexylamine sulfami...
- Primidone, Sodium channel alpha subunit blockerMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)● In Stock — US warehouse, ships to EU* Item #: P129217View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione
- SMILES
- CCC1(C(=O)NCNC1=O)C2=CC=CC=C2
- InChIKey
- DQMZLTXERSFNPB-UHFFFAOYSA-N
- InChI
- 1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16)
- Synonyms
- 5-Phenyl-5-ethyl-hexahydropyrimidine-4,6-dione | Primidone (Mysoline) | PRIMIDONE (USP-RS) | Pyrimidone ''Medi-pets''...
- Sodium CyclamateCAS: 139-05-9 EC Number: 205-348-9 PubChem CID: 23665706 Formula: C6H12NNaO3S Molecular Weight: 201.22Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.● In Stock — US warehouse, ships to EU* Item #: S109885View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- sodium;N-cyclohexylsulfamate
- SMILES
- C1CCC(CC1)NS(=O)(=O)[O-].[Na+]
- InChIKey
- UDIPTWFVPPPURJ-UHFFFAOYSA-M
- InChI
- 1S/C6H13NO3S.Na/c8-11(9,10)7-6-4-2-1-3-5-6;/h6-7H,1-5H2,(H,8,9,10);/q;+1/p-1
- Synonyms
- Assurgrin vollsuss | Cyclamate de sodium [INN-French] | Natriumzyklamate [German] | UDIPTWFVPPPURJ-UHFFFAOYSA-M | DB0...
- IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide)CAS: 861891-50-1 Formula: C19H23N3O2 Molecular Weight: 325.41◐ .Made to order · 8–12 wks Item #: I275848View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-methyl-3-(1-methylindol-3-yl)-4-(pentylamino)pyrrole-2,5-dione
- SMILES
- CCCCCNC1=C(C(=O)N(C1=O)C)C2=CN(C3=CC=CC=C32)C
- InChIKey
- SGLOMINNEBLJFF-UHFFFAOYSA-N
- InChI
- 1S/C19H23N3O2/c1-4-5-8-11-20-17-16(18(23)22(3)19(17)24)14-12-21(2)15-10-7-6-9-13(14)15/h6-7,9-10,12,20H,4-5,8,11H2,1-3H3
- Synonyms
- IM-54, >=98% (HPLC) | 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione; Necrosis Inhibitor, I...
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Frequently Asked Questions
How is the Necroptosis listing put together?
It draws on reported Necroptosis annotations within Apoptosis and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Necroptosis modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Necroptosis entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Necroptosis compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Necroptosis work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Necroptosis compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Necroptosis compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.