Sodium Cyclamate - analytical standard , CAS No.139-05-9

CAS: 139-05-9 Cat. No.: S109885 Molecular Weight: 201.22 Beilstein Registry Number: 4166868 EC Number: 205-348-9 PubChem CID: 23665706
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GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
Synonyms
Assurgrin vollsuss | Cyclamate de sodium [INN-French] | Natriumzyklamate [German] | UDIPTWFVPPPURJ-UHFFFAOYSA-M | DB00485 | HY-W014839 | MLS004773942 | Cyclohexylsulfamate sodium | 1I6F42RME1 | C19378 | Ciclamato sodico | Sodium cyclohexyl amidosulphate |
Storage
Protected from light,Room temperature
Shipped In
Normal
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Size
Status
Price
Qty
250mg
S109885-250mg
3

$38.90

$45.90
Save $7.00 (15.25%)
1g
S109885-1g
3

$108.90

$169.90
Save $61.00 (35.90%)
5g
S109885-5g
3

$399.90

$711.90
Save $312.00 (43.83%)
25g
S109885-25g
3

$1,142.90

$1,399.90
Save $257.00 (18.36%)
100g
S109885-100g
3
$3,199.90
Enter a quantity for the sizes you want to add.
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Why this grade

analytical standard Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 10 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Assurgrin vollsuss | Cyclamate de sodium [INN-French] | Natriumzyklamate [German] | UDIPTWFVPPPURJ-UHFFFAOYSA-M | DB00485 | HY-W014839 | MLS004773942 | Cyclohexylsulfamate sodium | 1I6F42RME1 | C19378 | Ciclamato sodico | Sodium cyclohexyl amidosulphate |
Specifications & Purity
analytical standard
Biochemical and Physiological Mechanisms
人可察觉的苯氨基磺酸盐甜味剂。使用动物模型研究其潜在致癌作用的第一代甜味剂。
Storage
Protected from light, Room temperature
Shipped In
Normal
Grade
Analytical standard
Names and Identifiers
Canonical SmilesC1CCC(CC1)NS(=O)(=O)[O-].[Na+]
IUPAC Namesodium;N-cyclohexylsulfamate
InChIKeyUDIPTWFVPPPURJ-UHFFFAOYSA-M
INCHI1S/C6H13NO3S.Na/c8-11(9,10)7-6-4-2-1-3-5-6;/h6-7H,1-5H2,(H,8,9,10);/q;+1/p-1
Isomeric SMILES C1CCC(CC1)NS(=O)(=O)[O-].[Na+]
WGK Germany 3
RTECS GV7350000
PubChem CID 23665706
Molecular Weight 201.22
Beilstein 4166868
Reaxy-Rn 4166868

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassSulfamic acid derivatives
SubclassCyclamates
Intermediate Tree Nodes Not available
Direct ParentCyclamates
Alternative Parents Sulfuric acid monoamides  Organopnictogen compounds  Organonitrogen compounds  Organic sodium salts  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAliphatic homomonocyclic compounds
Substituents Cyclamic_acid_derivative - Sulfuric acid monoamide - Organic sulfuric acid or derivatives - Organic alkali metal salt - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic sodium salt - Organic salt - Organonitrogen compound - Aliphatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as cyclamates. These are compounds containing a cyclohexylsulfamic acid moiety.
External Descriptors organic molecular entity
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA14 Tclin Carbonic anhydrase XIV (1305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TAS2R41 Tchem Taste receptor type 2 member 41 (57 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Ca7 Carbonic anhydrase VII (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
G2514544Certificate of AnalysisAug 28, 2024 S109885
G2514545Certificate of AnalysisAug 28, 2024 S109885
G2514546Certificate of AnalysisAug 28, 2024 S109885
G2514547Certificate of AnalysisAug 28, 2024 S109885
G2514548Certificate of AnalysisAug 28, 2024 S109885
G2514549Certificate of AnalysisAug 28, 2024 S109885
G2514550Certificate of AnalysisAug 28, 2024 S109885
G2514551Certificate of AnalysisAug 28, 2024 S109885
G2514552Certificate of AnalysisAug 28, 2024 S109885
G2514553Certificate of AnalysisAug 28, 2024 S109885
F1826158Certificate of AnalysisFeb 22, 2022 S109885

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Chemical and Physical Properties
SensitivityLight sensitive.
Melt Point(°C)>300°C
Molecular Weight201.220 g/mol
XLogP3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass201.044 Da
Monoisotopic Mass201.044 Da
Topological Polar Surface Area77.600 Ų
Heavy Atom Count12
Formal Charge0
Complexity205.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Documents & Articles
Citations of This Product
References
1. Guosheng Duan, Yang Wang, Leilei Sun, Zhean Bao, Bin Luo, Sinan Zheng, Zhizhen Ye, Jingyun Huang, Yingying Lu.  (2023)  Atomic Pinning of Trace Additives Induces Interfacial Solvation for Highly Reversible Zn Metal Anodes.  ACS Nano,      [PMID:37955634] [10.1021/acsnano.3c07257]
2. Jing Xiao, Jiayuan Tang, Jihong Chen, Lanlan Li, Shu Zhang, Xiaoli Xiong, Zhirong Zou.  (2023)  Rapid and selective detection of nitrite in ham sausage and water samples by a portable gas pressure meter.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2023.134914]
3. Ferry Saputra, Yu-Heng Lai, Rey Arturo T. Fernandez, Allan Patrick G. Macabeo, Hong-Thih Lai, Jong-Chin Huang, Chung-Der Hsiao.  (2021)  Acute and Sub-Chronic Exposure to Artificial Sweeteners at the Highest Environmentally Relevant Concentration Induce Less Cardiovascular Physiology Alterations in Zebrafish Larvae.  Biology-Basel,  10  (6): (548).  [PMID:34207293] [10.3390/biology10060548]
4. Chen Junzhe, Du Haiying, Xu Yifeng, Ma Boyu, Zheng Zhihong, Li Pengchan, Jiang Yuqiu.  (2021)  A turn-on fluorescent sensor based on coffee-ground carbon dots for the detection of sodium cyclamate.  JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS,  32  (10): (13581-13587).  [PMID:] [10.1007/s10854-021-05933-3]
5. Mohan Zhang, Xin Yang, Wan Xu, Xiaobo Cai, Mingxiang Wang, Yuying Xu, Peilin Yu, Jun Zhang, Yifan Zheng, Jiang Chen, Jun Yang, Xinqiang Zhu.  (2019)  Evaluation of the effects of three sulfa sweeteners on the lifespan and intestinal fat deposition in C. elegans.  FOOD RESEARCH INTERNATIONAL,      [PMID:31229125] [10.1016/j.foodres.2019.03.028]
6. Hongmei Zhang, Shixin Sun, Yanqing Wang, Zhenghao Fei, Jian Cao.  (2018)  Binding mechanism of five typical sweeteners with bovine serum albumin.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,      [PMID:30015031] [10.1016/j.saa.2018.07.013]
7. Shui Wang, Xiaowei Cheng, Baoli Liu, Yizhen Du, Jidong Wang.  (2015)  Temperature dependent solubility of sodium cyclamate in selected pure solvents and binary methanol + water mixed solvents.  FLUID PHASE EQUILIBRIA,      [PMID:] [10.1016/j.fluid.2015.01.012]
8. Dali Zhuo, Xiaoyu Dong, Linghuan Li, Ronghua Zeng, Chao Tan, Hong Luo, Zhirong Zou.  (2025)  Detection of Ca2+ in water samples and calcium gluconate oral liquids using gas pressure meter as portable detector.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.113116]
9. Rui Yang, Luji Yang, Jiahui Yang, Zhi-ang Li, Chengbin Zheng.  (2025)  Portable analytical system integrating purge and trap and microplasma optical emission spectrometry for online discriminative detection of NOx.  TALANTA,      [PMID:40024131] [10.1016/j.talanta.2025.127836]
10. Jing Xiao, Dali Zhuo, Jiayuan Tang, Jihong Chen, Chao Tan, Shu Zhang, Shichao Li, Zhirong Zou.  (2024)  Selective and sensitive detection of cyclamate in beverages using a portable pressure meter: A specific reaction-based analytical kit.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2024.110959]
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