PI4K

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  1. T-00127_HEV1
    CAS: 900874-91-1 PubChem CID: 4904109 Formula: C22H29N5O3 Molecular Weight: 411.50
    ◐ .Made to order · 8–12 wks Item #: T647156
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    IUPAC Name
    3-(3,4-dimethoxyphenyl)-2,5-dimethyl-N-(2-morpholin-4-ylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
    SMILES
    CC1=NC2=C(C(=NN2C(=C1)NCCN3CCOCC3)C)C4=CC(=C(C=C4)OC)OC
    InChIKey
    RITGMCAEZVMEQO-UHFFFAOYSA-N
    InChI
    1S/C22H29N5O3/c1-15-13-20(23-7-8-26-9-11-30-12-10-26)27-22(24-15)21(16(2)25-27)17-5-6-18(28-3)19(14-17)29-4/h5-6,13-14,23H,7-12H2,1-4H3
  2. UCT943
    CAS: 1450666-80-4 PubChem CID: 71711915 Formula: C22H20F3N5O Molecular Weight: 427.42
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: U649335
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    IUPAC Name
    [4-[5-amino-6-[4-(trifluoromethyl)phenyl]pyrazin-2-yl]phenyl]-piperazin-1-ylmethanone
    SMILES
    C1CN(CCN1)C(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C4=CC=C(C=C4)C(F)(F)F)N
    InChIKey
    GGOFGCMPKAWHEZ-UHFFFAOYSA-N
    InChI
    1S/C22H20F3N5O/c23-22(24,25)17-7-5-15(6-8-17)19-20(26)28-13-18(29-19)14-1-3-16(4-2-14)21(31)30-11-9-27-10-12-30/h1-8,13,27H,9-12H2,(H2,26,28)
    Synonyms
    (4-(5-amino-6-(4-(trifluoromethyl)phenyl)pyrazin-2-yl)phenyl)(piperazin-1-yl)methanone | Uct943 | [4-[5-Amino-6-[4-(t...
  3. PI4KIIIbeta-IN-10
    CAS: 1881233-39-1 PubChem CID: 71549093 Formula: C22H25N3O5S2 Molecular Weight: 475.6
    ◐ .Made to order · 8–12 wks Item #: P651260
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    IUPAC Name
    N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
    SMILES
    CC1=C(SC(=N1)NC(=O)C(C)(C)C)C2=CC(=C(C=C2)OC)S(=O)(=O)NC3=CC=C(C=C3)O
    InChIKey
    PLUYFBRIGUAKBR-UHFFFAOYSA-N
    InChI
    1S/C22H25N3O5S2/c1-13-19(31-21(23-13)24-20(27)22(2,3)4)14-6-11-17(30-5)18(12-14)32(28,29)25-15-7-9-16(26)10-8-15/h6-12,25-26H,1-5H3,(H,23,24,27)
    Synonyms
    A908340 | SCHEMBL14851574 | N-[5-[3-[(4-hydroxyphenyl)sulfamoyl]-4-methoxyphenyl]-4-methyl-1,3-thiazol-2-yl]-2,2-dime...
  4. GSK-A1
    CAS: 1416334-69-4 PubChem CID: 71116366 Formula: C29H27FN6O4S Molecular Weight: 574.63
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: G651371
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    IUPAC Name
    5-[2-amino-3-(4-morpholin-4-ylphenyl)benzimidazol-5-yl]-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide
    SMILES
    COC1=C(C=C(C=N1)C2=CC3=C(C=C2)N=C(N3C4=CC=C(C=C4)N5CCOCC5)N)S(=O)(=O)NC6=CC=CC=C6F
    InChIKey
    AJOGHKUZDLYXKS-UHFFFAOYSA-N
    InChI
    1S/C29H27FN6O4S/c1-39-28-27(41(37,38)34-24-5-3-2-4-23(24)30)17-20(18-32-28)19-6-11-25-26(16-19)36(29(31)33-25)22-9-7-21(8-10-22)35-12-14-40-15-13-35/hshow more
    Synonyms
    5-(2-Amino-1-(4-morpholinophenyl)-1H-benzimidazol-6-yl)-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide | 5-(2-Ami...
  5. PI-273
    CAS: 925069-34-7 PubChem CID: 17168969 Formula: C16H16ClN3O2S2 Molecular Weight: 381.9
    ◐ .Made to order · 8–12 wks Item #: P647169
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    IUPAC Name
    2-[(4-chlorobenzoyl)carbamothioylamino]-4-ethyl-5-methylthiophene-3-carboxamide
    SMILES
    CCC1=C(SC(=C1C(=O)N)NC(=S)NC(=O)C2=CC=C(C=C2)Cl)C
    InChIKey
    MIERMBQDBLFAFW-UHFFFAOYSA-N
    InChI
    1S/C16H16ClN3O2S2/c1-3-11-8(2)24-15(12(11)13(18)21)20-16(23)19-14(22)9-4-6-10(17)7-5-9/h4-7H,3H2,1-2H3,(H2,18,21)(H2,19,20,22,23)
  6. KDU731
    CAS: 1610610-48-4 PubChem CID: 76281701 Formula: C22H16N6O2 Molecular Weight: 396.40
    ◐ .Made to order · 8–12 wks Item #: K649480
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    IUPAC Name
    3-(4-carbamoylphenyl)-N-(5-cyanopyridin-2-yl)-N-methylpyrazolo[1,5-a]pyridine-5-carboxamide
    SMILES
    CN(C1=NC=C(C=C1)C#N)C(=O)C2=CC3=C(C=NN3C=C2)C4=CC=C(C=C4)C(=O)N
    InChIKey
    YTIYJNWWLQSAAU-UHFFFAOYSA-N
    InChI
    1S/C22H16N6O2/c1-27(20-7-2-14(11-23)12-25-20)22(30)17-8-9-28-19(10-17)18(13-26-28)15-3-5-16(6-4-15)21(24)29/h2-10,12-13H,1H3,(H2,24,29)
  7. AZ044
    CAS: 1800017-49-5 PubChem CID: 122184544 Formula: C24H27N3O3S
    ◐ .Made to order · 8–12 wks Item #: A669799
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    IUPAC Name
    4-[[[6-[1-(cyclopropylmethyl)-2-oxopyridin-4-yl]-1,3-benzothiazol-2-yl]amino]methyl]cyclohexane-1-carboxylic acid
    SMILES
    OC(=O)[C@H]1CC[C@H](CNC2=NC3=C(S2)C=C(C=C3)C2=CC(=O)N(CC3CC3)C=C2)CC1
    InChIKey
    LCUPEZBPGVQFLN-UHFFFAOYSA-N
    InChI
    1S/C24H27N3O3S/c28-22-12-19(9-10-27(22)14-16-1-2-16)18-7-8-20-21(11-18)31-24(26-20)25-13-15-3-5-17(6-4-15)23(29)30/h7-12,15-17H,1-6,13-14H2,(H,25,26)(show more
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

Which compounds are listed for PI4K?
Compounds associated with PI4K are grouped here under the PI3K/Akt/mTOR classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does PI4K sit within PI3K/Akt/mTOR?
PI4K is one target listing within the PI3K/Akt/mTOR classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from PI4K?
For compounds listed under PI4K, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for PI4K?
Browse the parent PI3K/Akt/mTOR listing to reach targets neighbouring PI4K, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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