Arrestin

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  1. ML 221, Antagonist of apelin receptor
    CAS: 877636-42-5 Formula: C17H11N3O6S Molecular Weight: 385.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: M286930
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    IUPAC Name
    [4-oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-nitrobenzoate
    SMILES
    C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)[N+](=O)[O-]
    InChIKey
    UASIRTUMPRQVFY-UHFFFAOYSA-N
    InChI
    1S/C17H11N3O6S/c21-14-8-13(10-27-17-18-6-1-7-19-17)25-9-15(14)26-16(22)11-2-4-12(5-3-11)20(23)24/h1-9H,10H2
    Synonyms
    5-[(4-Nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one | ML221 | 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4...
  2. TC-G 1001
    CAS: 494191-73-0 PubChem CID: 135468531 Formula: C17H11FN2O3S Molecular Weight: 342.34
    ◐ .Made to order · 8–12 wks Item #: T287556
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    IUPAC Name
    4-[(Z)-[2-(2-fluorophenyl)imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]benzoic acid
    SMILES
    C1=CC=C(C(=C1)N=C2NC(=O)C(=CC3=CC=C(C=C3)C(=O)O)S2)F
    InChIKey
    SYCKPHBALHXMIR-ZROIWOOFSA-N
    InChI
    1S/C17H11FN2O3S/c18-12-3-1-2-4-13(12)19-17-20-15(21)14(24-17)9-10-5-7-11(8-6-10)16(22)23/h1-9H,(H,22,23)(H,19,20,21)/b14-9-
    Synonyms
    4-[[2-[(2-Fluorophenyl)amino]-4-oxo-5(4H)-thiazolylidene]methyl]benzoic acid
  3. 5,6-Dihydroxyindole-2-carboxylic Acid
    CAS: 4790-08-3 Formula: C9H7NO4 Molecular Weight: 193.16
    ● In Stock — US warehouse, ships to EU* Item #: D330878
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    IUPAC Name
    5,6-dihydroxy-1H-indole-2-carboxylic acid
    SMILES
    C1=C2C=C(NC2=CC(=C1O)O)C(=O)O
    InChIKey
    YFTGOBNOJKXZJC-UHFFFAOYSA-N
    InChI
    1S/C9H7NO4/c11-7-2-4-1-6(9(13)14)10-5(4)3-8(7)12/h1-3,10-12H,(H,13,14)
    Synonyms
    5,6-Dihydroxy-1H-indole-2-carboxylic acid
  4. 7-Fluorotryptamine HCl
    CAS: 159730-09-3 Formula: C10H12ClFN2 Molecular Weight: 214.671
    ● In Stock — US warehouse, ships to EU* Item #: F353045
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    IUPAC Name
    2-(7-fluoro-1H-indol-3-yl)ethanamine;hydrochloride
    SMILES
    C1=CC2=C(C(=C1)F)NC=C2CCN.Cl
    InChIKey
    JWAZOMQARDNFMN-UHFFFAOYSA-N
    InChI
    1S/C10H11FN2.ClH/c11-9-3-1-2-8-7(4-5-12)6-13-10(8)9;/h1-3,6,13H,4-5,12H2;1H
    Synonyms
    EN300-7414884 | 2-(7-fluoro-1H-indol-3-yl)ethan-1-amine hydrochloride | AKOS016013411 | J-009638 | 1H-Indole-3-ethana...
  5. ELA-11 (human)
    CAS: 1784687-32-6 PubChem CID: 127043376 Formula: C58H90N16O13S2 Molecular Weight: 1283.57
    ◐ .Made to order · 8–12 wks Item #: E288238
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    IUPAC Name
    (2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2R)-2-amino-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyshow more
    SMILES
    CC(C)CC(C(=O)NC(CC1=CN=CN1)C(=O)NC(CO)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)C)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)N4CCCC4C(=O)O)NC(=O)C5CCCN5C(=O)C(CCSC)NCshow more
    InChIKey
    XXKPNJFJXZBRMX-HDKAIKTRSA-N
    InChI
    1S/C58H90N16O13S2/c1-32(2)25-39(68-52(81)43-16-10-21-72(43)54(83)38(19-24-89-5)66-47(76)36(59)30-88)49(78)67-40(27-35-28-62-31-64-35)50(79)70-42(29-75show more
  6. ML 221, Antagonist of apelin receptor
    CAS: 877636-42-5 Formula: C17H11N3O6S Molecular Weight: 385.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M426631
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    Technical Identifiers
    IUPAC Name
    [4-oxo-6-(pyrimidin-2-ylsulfanylmethyl)pyran-3-yl] 4-nitrobenzoate
    SMILES
    C1=CN=C(N=C1)SCC2=CC(=O)C(=CO2)OC(=O)C3=CC=C(C=C3)[N+](=O)[O-]
    InChIKey
    UASIRTUMPRQVFY-UHFFFAOYSA-N
    InChI
    1S/C17H11N3O6S/c21-14-8-13(10-27-17-18-6-1-7-19-17)25-9-15(14)26-16(22)11-2-4-12(5-3-11)20(23)24/h1-9H,10H2
    Synonyms
    5-[(4-Nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one
  7. MRS2365 trisodium, Agonist of P2Y 1 receptor
    CAS: 436847-09-5(free base) Formula: C13H16N5Na3O9P2S Molecular Weight: 549.28
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: M612047
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    Technical Identifiers
    Synonyms
    [[(1R,2R,3S,5S)-4-(6-amino-2-methylsulfanylpurin-9-yl)-2,3-dihydroxy-1-bicyclo[3.1.0]hexanyl]methoxy-oxidophosphoryl]...
  8. TRV027, Type-1 angiotensin II receptor antagonist
    CAS: 1234510-46-3 PubChem CID: 3082475 Formula: C43H67N13O10 Molecular Weight: 926.1
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .US Made to order · 2–4 wks Item #: rp175328
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    Technical Identifiers
    IUPAC Name
    (2R)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutashow more
    SMILES
    CNCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(=O)O)C)Cc1[nH]cnc1)[C@H](CC)C)Cc1ccc(cc1)O)C(C)C)CCCN=C(show more
    InChIKey
    XIEWFECSPPTVQN-KMIMAYJXSA-N
    InChI
    1S/C43H67N13O10/c1-7-24(4)35(40(63)53-31(19-27-20-47-22-49-27)41(64)56-17-9-11-32(56)38(61)50-25(5)42(65)66)55-37(60)30(18-26-12-14-28(57)15-13-26)52-show more
    Synonyms
    TRV 027 [WHO-DD] | Sar-val-tyr-ile-his-pro-d-ala-oh | TRV120027 | TRV-120027 | D-Alanine, N-methylglycyl-L-arginyl-L-...
  9. UNC9994 hydrochloride
    CAS: 2108826-33-9 PubChem CID: 121230971 Formula: C21H23Cl3N2OS Molecular Weight: 457.84
    ◐ .Made to order · 8–12 wks Item #: U647226
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    Technical Identifiers
    IUPAC Name
    5-[3-[4-(2,3-dichlorophenyl)piperidin-1-yl]propoxy]-1,3-benzothiazole;hydrochloride
    SMILES
    C1CN(CCC1C2=C(C(=CC=C2)Cl)Cl)CCCOC3=CC4=C(C=C3)SC=N4.Cl
    InChIKey
    MTDQOQYYKZUEEK-UHFFFAOYSA-N
    InChI
    1S/C21H22Cl2N2OS.ClH/c22-18-4-1-3-17(21(18)23)15-7-10-25(11-8-15)9-2-12-26-16-5-6-20-19(13-16)24-14-27-20;/h1,3-6,13-15H,2,7-12H2;1H
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the Arrestin listing put together?
It draws on reported Arrestin annotations within GPCR/G Protein and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an Arrestin modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Arrestin entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Arrestin compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Arrestin work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Arrestin compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Arrestin compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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