Separase

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  1. Sepin-1
    CAS: 163126-81-6 PubChem CID: 2736269
    ◐ .Made to order · 8–12 wks Item #: S1354149
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    Technical Identifiers
    IUPAC Name
    2,2-dimethyl-5-nitro-3-oxidobenzimidazol-1-ium 1-oxide
    SMILES
    CC1(N(C2=C([N+]1=O)C=CC(=C2)[N+](=O)[O-])[O-])C
    InChIKey
    YLVSVJDCTDBERH-UHFFFAOYSA-N
    InChI
    1S/C9H9N3O4/c1-9(2)10(13)7-4-3-6(12(15)16)5-8(7)11(9)14/h3-5H,1-2H3
  2. SIC5-6
    CAS: 2410846-16-9 PubChem CID: 154827475
    ◐ .Made to order · 8–12 wks Item #: S1427666
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    IUPAC Name
    3-[4-(1H-indol-3-yl)-1-(4-iodophenyl)sulfonylpiperidin-4-yl]-1H-indole
    SMILES
    C1CN(CCC1(C2=CNC3=CC=CC=C32)C4=CNC5=CC=CC=C54)S(=O)(=O)C6=CC=C(C=C6)I
    InChIKey
    JRVKJWXBSOQUOI-UHFFFAOYSA-N
    InChI
    1S/C27H24IN3O2S/c28-19-9-11-20(12-10-19)34(32,33)31-15-13-27(14-16-31,23-17-29-25-7-3-1-5-21(23)25)24-18-30-26-8-4-2-6-22(24)26/h1-12,17-18,29-30H,13-show more
  3. SIC5-6
    CAS: 2410846-16-9 PubChem CID: 154827475
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: S1496647
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  4. Sepin-1
    CAS: 163126-81-6 PubChem CID: 2736269
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: S1495081
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the Separase listing put together?
It draws on reported Separase annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Separase modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Separase entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Separase compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Separase work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Separase compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Separase compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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