Methanol

​Product Manager

Sandra Forbes

​

Recent Literature

An anionic iridium complex, [Cp*Ir(2,2'-bpyO)(OH)][Na], serves as a versatile and highly effective catalyst for the transfer hydrogenation of ketones and imines using methanol as the hydrogen source under base-free conditions. The reaction demonstrates excellent tolerance to nitro, cyano, and ester functional groups.

R. Wang, X. Han, J. Xu, P. Liu, F. Li, J. Org. Chem., 2020, 85, 2242-2249.

DOI: 10.1021/acs.joc.9b02957

An anionic iridium complex [Cp*Ir(2,2'-bpyO)(OH)][Na] is a general and highly efficient catalyst for transfer hydrogenation of ketones and imines with methanol as hydrogen source under base-free conditions. Nitro, cyano, and ester groups were tolerated under the reaction conditions.

R. Wang, X. Han, J. Xu, P. Liu, F. Li, J. Org. Chem., 2020, 85, 2242-2249.

DOI: 10.1021/acs.joc.9b02957

Additionally, an air- and moisture-stable manganese pincer complex efficiently catalyzes the semireduction of a wide range of alkynes, yielding the corresponding (Z)-olefins in high yields. This reaction is both stereo- and chemoselective and can be readily scaled up.

J. Sklyaruk, V. Zubar, J. C. Borghs, M. Rueping, Org. Lett., 2020, 22, 6067-6071.

DOI: 10.1021/acs.orglett.0c02151

Quoted from: https://www.organic-chemistry.org/chemicals/reductions/methanol.shtm

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