Sodium Benzoate: Uses, Purity & Lab FAQs
Sodium Benzoate: Uses, Purity & Lab FAQs
Sodium benzoate is a versatile organic-synthesis reagent widely employed in the preparation of benzene-based derivatives including 5-pyrazolinone derivatives, aminoflavones, and trihydroxybenzoyl flavanoid analogs.
- Chemical Name
- Sodium benzoate
- Molecular Formula
- C₇H₅NaO₂
- Molecular Weight
- 144.10 g/mol
- Primary Research Use
- Synthesis of 5-pyrazolinone derivatives, aminoflavones, and trihydroxybenzoyl flavanoid analogs
- Physical Form
- White crystalline powder
- Aladdin SKU
- S104128
What Is Sodium Benzoate and Why Is It Used in Research?
Sodium benzoate (C₇H₅NaO₂) is the sodium salt of benzoic acid. In research settings it serves as a key starting material or coupling partner in the synthesis of benzene-based derivatives. Documented applications include the preparation of 5-pyrazolinone derivatives, as well as aminoflavones and trihydroxybenzoyl flavanoid analogs. Its good water solubility, stability, and reliable reactivity make it a convenient source of the benzoate moiety in multi-step organic transformations.
Common Synthesis Applications
Sodium benzoate participates in several important synthetic pathways:
- 5-Pyrazolinone derivatives: Sodium benzoate acts as a benzoylating source or condensation partner, enabling the construction of the pyrazolinone heterocyclic core with pendant benzoate groups.
- Aminoflavone synthesis: The compound contributes the benzoate ester moiety in routes toward aminoflavone scaffolds, which are of interest as potential bioactive molecules.
- Trihydroxybenzoyl flavanoid analogs: In flavanoid analog synthesis, sodium benzoate facilitates introduction of the benzoyl group onto polyphenolic frameworks.
Researchers should optimize reaction conditions (solvent, temperature, base) according to the specific derivative target.
Handling, Storage, and Safety Guidelines
Follow standard laboratory safety protocols when working with sodium benzoate:
- Storage: Store in a cool, dry, well-ventilated area in a tightly sealed container, away from incompatible materials such as strong oxidizers and strong acids.
- Personal Protective Equipment (PPE): Wear appropriate gloves, safety eyewear, and a lab coat. Avoid generating dust during weighing.
- Disposal: Dispose of waste in accordance with applicable local, regional, and national regulations.
- SDS: Always consult the current Safety Data Sheet (SDS) available on the Aladdin Scientific product page (SKU S104128) before use.
Note: Specific GHS hazard classifications and first-aid measures should be confirmed in the official SDS.
Ordering and Product Specifications
Aladdin Scientific supplies sodium benzoate under SKU S104128. When placing an order or evaluating the product, consider the following:
- Purity grade: Confirm the exact purity specification on the product detail page before purchase to ensure suitability for your application.
- Available pack sizes: Multiple quantities may be available; contact Aladdin Scientific for bulk pricing or custom requirements.
- Documentation: Certificate of Analysis (CoA), SDS, and structural confirmation data are available upon request.
- Lead time: Check current stock status on the product page or contact customer service for estimated delivery timelines.
Frequently asked questions
What is sodium benzoate used for in laboratory synthesis?
Sodium benzoate is used as a reagent in the synthesis of benzene-based derivatives, including 5-pyrazolinone derivatives, aminoflavones, and trihydroxybenzoyl flavanoid analogs. It serves as a convenient and stable source of the benzoate moiety in multi-step organic reactions.
What purity grade of sodium benzoate does Aladdin Scientific offer for SKU S104128?
The specific purity grade for SKU S104128 should be confirmed directly on the Aladdin Scientific product detail page or by contacting customer service, as specifications may be updated. A Certificate of Analysis (CoA) is available upon request for lot-specific verification.
How should sodium benzoate be stored to maintain its quality?
Sodium benzoate should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from strong oxidizers and strong acids. Proper storage conditions help preserve purity and prevent degradation over time.
Can sodium benzoate be used in aqueous reaction systems?
Yes, sodium benzoate has good water solubility, which makes it compatible with aqueous or mixed aqueous-organic reaction systems. Researchers should verify compatibility with specific reaction conditions and co-reagents for their target synthesis.
How do I request a Safety Data Sheet (SDS) or Certificate of Analysis (CoA) for sodium benzoate S104128?
The SDS is typically available for download on the Aladdin Scientific product page for SKU S104128. For lot-specific Certificates of Analysis, please contact Aladdin Scientific customer service with your lot number and order details.
References
- Aladdin Scientific. Sodium benzoate, SKU S104128. Product description and specifications.
- March, J. Advanced Organic Chemistry: Reactions, Mechanisms, and Structure. Wiley. General reference for benzoylation reactions.
Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.