C-H Functionalization

DDQ (2,3-dichloro-5,6-dicyanobenzoquinone), which exhibits stronger oxidizing properties than 1,4-benzoquinone, serves as a reagent in oxidative coupling and cyclization reactions, as well as in the dehydrogenation of hydroaromatic compounds.

The "White catalyst", developed by Professor M. Christina White and her team at the University of Illinois-Urbana, has proven to be an outstanding catalyst for the functionalization of allylic carbon centers.

Professor Phil Baran and his team have created a new reagent called N-Hydroxytetrachlorophthalimide (H401609), which offers a cost-effective, scalable, and safe alternative for commonly used chemical transformations such as allylic oxidations, as well as Negishi and Suzuki-Miyaura cross-coupling ...

The core of the chemical industry revolves around the synthesis of heteroaromatic and aromatic compounds. Given the escalating demand for novel chemical entities amidst dwindling resources and tight timelines imposed on research projects, there is a pressing need for a swift method to diversify ...

MCAT-53™, a novel ruthenium catalyst, simplifies C-H activated C-C coupling in water by eliminating extra steps and avoiding solvents like NMP.

Professor Karl Anker Jørgensen and his research team have synthesized (R)- and (S)-α,α-bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether compounds, which excel as chiral organocatalysts for the direct and asymmetric α-functionalization process of aldehydes.

The Du Bois group at Stanford University has achieved significant advancements in Rh-catalyzed C–H amination through oxidative cyclization of carbamate, sulfamate, sulfamide, urea, and guanidine substrates. This methodology produces 1,2- and 1,3-heteroatom motifs masked within 5- and ...

N-Bromosuccinimide (NBS) is a brominating and oxidizing agent that is used as source for bromine in radical reactions (for example: allylic brominations) and various electrophilic additions. The NBS bromination of substrates such as alcohols and amines, followed by elimination of HBr in the ...

Trimethylamine borane, also known as trimethylamine complex with borane or trimethylamine borane adduct, is a chemical compound with the formula (CH3)3N·BH3. It is a coordination complex formed by the reaction between trimethylamine (N(CH3)3) and borane (BH3).

Diborane (B2H6), the simplest borane, is a useful reagent with many applications, but it is pyrophoric, gaseous and not convenient to handle. There is a wide range of boranes: Decaborane for example is not as reactive as diborane and is used as reducing agent too.

Bis(pinacolato)diboron is a covalent compound containing two boron atoms and two pinacolato ligands. It has the formula [(CH3)4C2O2B]2; the pinacol groups are sometimes abbreviated as "pin", so the structure is sometimes represented as B2pin2. It is a colourless solid that is soluble in organic ...

N-Bromosaccharin

Benzoyl peroxide is a chemical compound with structural formula (C6H5−C(=O)O−)2, often abbreviated as (BzO)2. In terms of its structure, the molecule can be described as two benzoyl (C6H5−C(=O)−, Bz) groups connected by a peroxide (−O−O−). It is a white granular solid with a faint ...