Amino acid dehydrogenases catalyze oxidative deamination or reductive amination between amino acids and their corresponding α-keto acids. Through NAD(H), NADP(H), or flavin cofactors, these enzymes connect nitrogen metabolism, central carbon metabolism, and cellular redox status. They are also ...
Topic
reductive amination
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
8 resources · protocols, FAQs & articles
In 2024, Reber and colleagues from the process research and development team at the Swiss biopharmaceutical company Idorsia Pharmaceuticals Ltd. (Idorsia) reported the kilogram-scale synthesis of ACT-1014-6470, an antagonist of complement C5a receptor 1 (C5aR1), in Organic Process Research & ...
α-Picoline-borane, 2-Methylpyridine borane, PICB
α-Picoline-borane, 2-Methylpyridine borane, PICB
Converting aldehydes/ketones into amines is one of the most common C–N bond-forming approaches in pharmaceutical synthesis, monomer modification for materials, and fine chemical manufacturing. Reductive amination is popular largely because it can often be done “one-pot”: the carbonyl and ...
Tris(dimethylamino)phosphine may serve as a deoxygenation and desulfurization reagent.
α-Picoline-borane, 2-Methylpyridine borane, PICB
Aladdin Reagents Company is able to offer a range of BINOL-derived chiral phosphoric acids in its asymmetric catalyst/ligand product portfolio. This class of well-established chiral Brønsted acid catalysts has been increasingly used in efficient conversion reactions.
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Techniques often explored alongside immunological experiments.