IR-820 - Moligand™, 10 mM in DMSO , CAS No.172616-80-7

CAS: 172616-80-7 Cat. No.: I1496544 Molecular Weight: 849.47 EC Number: 812-320-5
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Desiccated,Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
I1496544-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$58.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 20 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals.

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Desiccated, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Names and Identifiers
Isomeric SMILES CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)CCCCS(=O)(=O)[O-])/C=C/C4=C(/C(=C\C=C\5/C(C6=C(N5CCCCS(=O)(=O)[O-])C=CC7=CC=CC=C76)(C)C)/CCC4)Cl)C.[Na+]
WGK Germany 3
Molecular Weight 849.47
Reaxy-Rn 18937027
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18937027&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Melt Point(°C)>300°C
Documents & Articles
Citations of This Product
References
1. Jing Liu, Endian Cui, Qun Zhang, Denghui Xie.  (2023)  MoS2-based nanocomposites with high photothermal conversion efficiency for combinational photothermal/photodynamic tumor therapy.  JOURNAL OF ALLOYS AND COMPOUNDS,      [PMID:] [10.1016/j.jallcom.2023.172489]
2. Xirui Duan, Hailong Tian, Shuwen Zheng, Jianmei Zhu, Chan Li, Bo He, Lei Li, Hao Jiang, Shuaijun Lu, Yumei Feng, Gary T. Bentley, Wei Zhang, Canhua Huang, Wei Gao, Na Xie, Ke Xie.  (2023)  Photothermal-Starvation Therapy Nanomodulator Capable of Inhibiting Colorectal Cancer Recurrence and Metastasis by Energy Metabolism Reduction.  Advanced Healthcare Materials,      [PMID:37543843] [10.1002/adhm.202300968]
3. Wang Shuqi, Zhou Li, Tian Hailong, Li Bowen, Su Miao, Li Qiong, Nice Edouard C., Huang Canhua, Shao Jichun, He Tao.  (2023)  Site-specific nanomodulator capable of modulation apoptosis for enhanced colorectal cancer chemo-photothermal therapy.  JOURNAL OF NANOBIOTECHNOLOGY,  21  (1): (1-15).  [PMID:36670444] [10.1186/s12951-023-01779-5]
4. Hang Hu, Defeng Xu, Qingbo Xu, Yuxiang Tang, Jun Hong, Yu Hu, Jianhao Wang, Xinye Ni.  (2023)  Reduction-responsive worm-like nanoparticles for synergistic cancer chemo-photodynamic therapy.  Materials Today Bio,      [PMID:36647538] [10.1016/j.mtbio.2023.100542]
5. Kui Wang, Guo-Jie Gao, Xiao-Yan Wang.  (2022)  Photooxidation of IR-820 by Calixpyridinium-Induced Assembled Material and Its pH-Controlled Visual Multicolor Luminescence.  CHINESE JOURNAL OF CHEMISTRY,  40  (9): (1045-1052).  [PMID:] [10.1002/cjoc.202100802]
6. Lijun Zhu, Jianjun Chen, Ting Yan, Gulinigaer Alimu, Xueliang Zhang, Shuang Chen, Mutalifu Aimaiti, Rong Ma, Nuernisha Alifu.  (2021)  Near-infrared emissive polymer-coated IR-820 nanoparticles assisted photothermal therapy for cervical cancer cells.  Journal of Biophotonics,  14  (11): (e202100117).  [PMID:34331509] [10.1002/jbio.202100117]
7. Zhou Yun, Sun Xuanzi, Zhou Liansuo, Zhang Xiaozhi.  (2020)  pH-Sensitive and Long-Circulation Nanoparticles for Near-Infrared Fluorescence Imaging-Monitored and Chemo-Photothermal Synergistic Treatment Against Gastric Cancer.  Frontiers in Pharmacology,      [PMID:33381047] [10.3389/fphar.2020.610883]
8. Yixun Jin, Jia Huang, Yuming Tang, Zengyue Li, Amin Zhang, Ziyun Yang, Jiani Song, Xinyang Huang, Yaya Bai, Chao Sun, Xuejiao Wu, Jin Cheng, Lifu Wang, Qian Zhang, Weiyan Yao.  (2024)  Boosting ferroptosis by intervention of redox balance and synergetic with photothermal/photodynamic therapy for suppression of pancreatic cancer.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.154569]
9. Yaxue Liu, Yu Li, Junlong Chen, Pei Xie, Zongning Yin.  (2025)  Construction of fibrin-targeted Nanoparticles for Imaging Diagnosis and Treatment of Arterial Thrombosis.  Nanoscale,      [PMID:39992663] [10.1039/D4NR05377J]
10. Xufeng Lu, Xiaodong Chen, Chengyin Lin, Yongdong Yi, Shengsheng Zhao, Bingzi Zhu, Wenhai Deng, Xiang Wang, Zuoliang Xie, Shangrui Rao, Zhonglin Ni, Tao You, Liyi Li, Yingpeng Huang, Xiangyang Xue, Yaojun Yu, Weijian Sun, Xian Shen.  (2024)  Elesclomol Loaded Copper Oxide Nanoplatform Triggers Cuproptosis to Enhance Antitumor Immunotherapy.  Advanced Science,      [PMID:38430531] [10.1002/advs.202309984]
11. Yuanxin Pian, Yan Hao, Yuxin Guo, Shiqi Wu, Saijiao Tang, Jiaqi Li, Xinya Lu, Xiaoya Sun, Zhaowen Tan, Tianyu Zhu, Yuxiang Tang, Defeng Xu, Hang Hu.  (2025)  Exploration of using α-crocin for drug encapsulation and delivery.  JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.jddst.2025.106716]
12. Li Fangling, Liu Chengjing, Gu Wenyi, Xu Qianhe, Li Dongmei, Cao Dongdong, Liu Zhiyong.  (2025)  Nanocomplex hyaluronic acid/ganciclovir@ZIF-8 for ganciclovir efficient delivery and targeted anti-KSHV treatment.  Cancer Nanotechnology,  16  (1): (1-20).  [PMID:] [10.1186/s12645-024-00303-0]
13. Peng Hu, Xiaowen Peng, Shuang Zhao, Fan Li, Guoye Yang, Wujie Guo, Shuling Yu, Jianjun Cheng, Juan Cen, Jiahua Shi.  (2024)  Self-sacrificed construction of versatile nanoadjuvant for synergistically enhanced immunogenic cell death and improved anti-tumor immunity.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.152033]
14. Xia Dong, Jie Liang, Afeng Yang, Zhiyong Qian, Deling Kong, Feng Lv.  (2019)  Fluorescence imaging guided CpG nanoparticles-loaded IR820-hydrogel for synergistic photothermal immunotherapy.  BIOMATERIALS,      [PMID:31034980] [10.1016/j.biomaterials.2019.04.024]
15. Shi-Cheng Tian, Xun-Huan Song, Ke-Ke Feng, Cheng-Lei Li, Yi-Fan Tu, Yong-Shan Hu, Jing-Wei Shao.  (2025)  Self-oxygenating nanoplatform integrating CRISPR/Cas9 gene editing and immune activation for highly efficient photodynamic therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:40262200] [10.1016/j.jcis.2025.137632]
16. Duan Xirui, Tian Hailong, Peng Peilan, Zhou Ping, Ding Ning, Liu Guowen, Bentley Gary T., Huang Canhua, Yang Jun, Xie Ke.  (2025)  Hyaluronic acid-tailored prodrug nanoplatforms for efficiently overcoming colorectal cancer chemoresistance and recurrence by synergistic inhibition of cancer cell stemness.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-19).  [PMID:40660238] [10.1186/s12951-025-03484-x]
17. Zengyue Li, Nan Kang, Yixun Jin, Weiyan Yao, Jin Cheng, Zimei Liu, Xiaoqing Qian, Qian Zhang.  (2025)  A pH-Responsive MnCO3 Nanoplatform with MRI/NIR Imaging Guidance for Chemo-Photothermal-Photodynamic Synergy of Pancreatic Cancer.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.5c04580]
18. Jing Zuo, Yichun Huang, Hailong Tian, Siyuan Qin, Yonghao Yan, Han Yan, Yining Jiang, Lei Li, Shiqi Wang, Yongfeng Jia, Yuan Zhao, Canhua Huang.  (2026)  H-ferritin engineered nanoplatform reprograms metabolism and immunity for glioblastoma immunotherapy.  JOURNAL OF CONTROLLED RELEASE,      [PMID:41506381] [10.1016/j.jconrel.2026.114613]
19. Yanrui Liang, Guodong Shen, Keyu He, Weisheng Wang, Bing Xiao, Tian Lin, Huilin Huang, Zhenyuan Li, Yingxin Ren, Zean Wang, Yiheng Luo, Weihong Guo, Yanfeng Hu, Guoxin Li.  (2026)  Multimodal Imaging By Polydopamine Nanoparticles for Effective Pre- and Intra-Operative Lymph-Node Screening in Gastric Cancer Using Mice Model.  International Journal of Nanomedicine,      [PMID:] [10.2147/IJN.S555760]
20. Mengyu Xu, Lihua Ma, Min Liu, Yuanxin Chen, Xianjun Wang, Lijuan Wang, Yanxi Zhu.  (2026)  Construction of Rough Surfaces Based on Zirconium Metal–Organic Frameworks to Enhance Photothermal and Photodynamic Therapy for Multiple Myeloma.  Biomaterials Research,      [PMID:41728073] [10.34133/bmr.0330]
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