Recombinant TNF-alpha Antibody - Primary antibody, specific to TNFSF2/TNFa, INHIBITOR of TNF-alpha inhibitor, INHIBITOR of TNF-alpha inhibitor

CAS: 170277-31-3 Cat. No.: Ab304389
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human
Isotype
Human IgG1
Conjugation
Unconjugated
Size
Germany (EU)
USA*
Price
Qty
100μg
Ab304389-100μg
Made to order · 8–12 wks
€38.09
Enter a quantity for the sizes you want to add.
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Why this grade

Animal Free,Carrier Free,Recombinant,ExactAb™,Low Endotoxin,Azide Free,Validated,PBS Only,≥95%(SDS-PAGE&SEC-HPLC),See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,PBS Only,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Infliximab (anti-TNF-alpha) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α, prevents the interaction of TNF-α with TNF-α receptor (TNFR1 and TNFR2), has the potential for treatment of Crohn's disease and rheumatoid arthritis.  

Specifications

Product Name
Recombinant TNF-alpha Antibody - Primary antibody, specific to TNFSF2/TNFa, INHIBITOR of TNF-alpha inhibitor
Synonyms
Infliximab | Remicade | Remsima | Inflectra | Avakine | CT-P13 | APC1 antibody | APC1 protein antibody | Cachectin antibody | DIF antibody | Differentiation inducing factor antibody | Macrophage cytotoxic factor antibody | Tnf antibody | TNF superfamily m
Specifications & Purity
Animal Free,Carrier Free,Recombinant,ExactAb™,Low Endotoxin,Azide Free,Validated,PBS Only,≥95%(SDS-PAGE&SEC-HPLC),See COA
Biochemical and Physiological Mechanisms
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is i
Host species
Human
Specificity
TNFSF2/TNFa
Conjugation
Unconjugated
Grade
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, PBS Only, Recombinant, Validated
Action Type
INHIBITOR
Mechanism of action
INHIBITOR of TNF-alpha inhibitor
Light Chain Type
kappa
SDS-PAGE
27.6 kDa (Light Chain) & 52.7 kDa (Heavy Chain), under reducing conditions; 186.7 kDa, under non-reducing conditions.
Purification Method
Protein A purified
Concentration
See COA
CAS
170277-31-3
Storage and Shipping
Form
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Store at -80℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
TNF Tclin Tumor necrosis factor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
ZJ25F1230259Certificate of AnalysisDec 15, 2025 Ab304389
Solution Calculators
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