BRD 9757 - ≥98%(HPLC) , CAS No.1423058-85-8

CAS: 1423058-85-8 Cat. No.: B286988 Fórmula: C6H9NO2 Peso molecular: 127.14 Número EC: 808-585-1
Disponible para pedir
GRADE & PURITY ≥98%(HPLC)
Synonyms
AKOS040746645 | N-Hydroxy-1-cyclopentene-1-carboxamide | N-hydroxycyclopentene-1-carboxamide | cyclopentenylhydroxamate | FBJ | BDBM50429525 | Q27215669 | HY-117554 | YGC05885 | 1423058-85-8 | CHEBI:125319 | SCHEMBL6880360 | cyclopentenyl hydroxamic acid
Storage
Conservar a -20°C
Shipped In
Hielera + almohadillas de hielo
Size
Alemania (EU)
USA*
Price
Qty
5mg
B286988-5mg
Fabricado bajo pedido · 8–12 semanas
260,23€
10mg
B286988-10mg
Fabricado bajo pedido · 8–12 semanas
367,83€
25mg
B286988-25mg
Fabricado bajo pedido · 8–12 semanas
586,50€
50mg
B286988-50mg
Fabricado bajo pedido · 8–12 semanas
937,07€
Enter a quantity for the sizes you want to add.
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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Conservar a -20°C Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

BRD9757 es un inhibidor de HDAC6 potente, sin capa y selectivo con un IC50 de 30 nM. BRD9757 muestra una excelente selectividad hacia HDAC6 frente a las HDAC de clase I (>20 veces) y clase II (>400 veces)

Specifications

Sinónimos
AKOS040746645 | N-Hydroxy-1-cyclopentene-1-carboxamide | N-hydroxycyclopentene-1-carboxamide | cyclopentenylhydroxamate | FBJ | BDBM50429525 | Q27215669 | HY-117554 | YGC05885 | 1423058-85-8 | CHEBI:125319 | SCHEMBL6880360 | cyclopentenyl hydroxamic acid
Especificaciones y pureza
≥98%(HPLC)
Mecanismos bioquímicos y fisiológicos
Inhibidor potente y selectivo de HDAC6 (IC50= 30 nM). Muestra selectividad por HDAC6 frente a HDACS de clase I (>20 veces) y HDACs de clase II (>400 veces).
Condiciones de almacenamiento de almacenamiento
Conservar a -20°C
Enviado en
Hielera + almohadillas de hielo
Tipo de acción
INHIBITOR
Pureza
≥98%(HPLC)
Nombres e identificadores
Sonrisas canónicasC1CC=C(C1)C(=O)NO
IUPAC NameN-hydroxycyclopentene-1-carboxamide
InChIKeyRYYGSXXWQSXKRP-UHFFFAOYSA-N
INCHI1S/C6H9NO2/c8-6(7-9)5-3-1-2-4-5/h3,9H,1-2,4H2,(H,7,8)
Isómeros SMILES C1CC=C(C1)C(=O)NO
WGK Alemania 3
Peso molecular 127.14
Reaxy-Rn 23386260
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23386260&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClaseCarboxylic acids and derivatives
SubclassCarboxylic acid derivatives
Intermediate Tree Nodes Carboxylic acid amides - Primary carboxylic acid amides
Direct ParentHydroxamic acids
Alternative Parents Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic homomonocyclic compounds
Substituents Hydroxamic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic homomonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as hydroxamic acids. These are compounds containing a hydroxamic acid functional group in which a hydroxylamine is inserted into a carboxylic acid. Its general structure is R-CO-NH-OH, with an R as an organic residue.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
HDAC6 Tclin Histone deacetylase 6 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HDAC1 Tclin Histone deacetylase 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HDAC3 Tclin Histone deacetylase 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HDAC8 Tclin Histone deacetylase 8 (4516 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC2 Tclin Histone deacetylase 2 (3971 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC3 Tclin Histone deacetylase 3 (3654 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC4 Tclin Histone deacetylase 4 (2328 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC9 Tclin Histone deacetylase 9 (708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC7 Tclin Histone deacetylase 7 (1047 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Hdac1 Histone deacetylase 1 (93 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac5 Histone deacetylase 5 (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadSolvent:water, Max Conc. mg/mL: 6.36, Max Conc. mM: 50; Solvent:DMSO, Max Conc. mg/mL: 12.71, Max Conc. mM: 100
Peso molecular127.140 g/mol
XLogP30.400
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass127.063 Da
Monoisotopic Mass127.063 Da
Topological Polar Surface Area49.300 Ų
Heavy Atom Count9
Formal Charge0
Complexity151.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Calculadoras de soluciones
Reseñas

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