AMPK

Explore AMPK beta 1 Mouse mAb (Ab351150) specs, biological context, and application guidance for WB, IHC, and IF. Supplied in PBS formulation.

Dietary restriction, Rapamycin, α-ketoglutarate (AKG), and Carglumic Acid influence aging-related processes through nutrient availability, mTOR signaling, central metabolism, and nitrogen metabolism, respectively. Their effects involve autophagy, proteostasis, mitochondrial function, and ...

Both fasting and ketogenic diets can enhance fatty acid utilization and ketone body production. AMPK–MNK–eIF4E signaling and 5′UTR-dependent selective translation participate in this nutritional adaptation and influence the ability of pancreatic cancer to adapt to a ketogenic metabolic ...

The core of white adipose tissue browning is not simply a reduction in lipid storage but the reconstruction of mitochondrial oxidative and thermogenic programs. Natural products such as Hyperforin, Capsaicin, Resveratrol, Berberine, and Fucoxanthin can affect the PGC-1α-UCP1 thermogenic axis at ...

Aging involves persistent dysregulation of nutrient sensing, energy metabolism, protein homeostasis, and chronic inflammation. IIS, mTOR, AMPK, NF-κB, and Sirtuins are interconnected through nodes including AKT, FOXO, ULK1, and NAD⁺ and jointly regulate cell growth, autophagy, stress ...

Metabolic disorders involve multiple abnormalities, including insulin resistance, dysregulated glucose and lipid metabolism, chronic inflammation, and oxidative stress. Natural products possess diverse structural classes and molecular targets and can improve metabolic homeostasis by regulating ...

Autophagy is a cellular quality control system that delivers cytoplasmic components, damaged organelles, protein aggregates, or intracellular pathogens to lysosomes for degradation. Its core significance is not simply “increased degradation,” but rather the maintenance of cellular ...