Fas

The Fas pathway is one of the classical signaling axes of death receptor-mediated apoptosis and occupies a central position in the maintenance of immune homeostasis, the elimination of activated lymphocytes, the regulation of tissue injury, and tumor immune escape. Its research value lies not ...

Sphingolipid metabolism is not merely a process of membrane-lipid turnover, but an important signaling layer linking death-receptor activation, mitochondrial injury, inflammasome assembly, and cell-fate determination.

Apoptosis is a programmed cell death process. Unlike necrosis, apoptosis is an orderly, gene-regulated, and active cell death process. Apoptosis plays an important role in the development of organisms, the maintenance of tissue homeostasis, the regulation of the immune system, and the occurrence ...