Lampalizumab (anti-Complement Factor D) - Anticuerpo primario, specific to CFD, >95%, Human IgG1, Antibody of complement factor D, Antibody of complement factor D

CAS: 1278466-20-8 Cat. No.: Ab175571

GRADE & PURITY Animal Free, Carrier Free, Recombinant, Validated, ExactAb™, Low Endotoxin, Azide Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

Humano

Reactive species

Conejo, Humano, Mono cynomolgus

Isotype

Human IgG1

Conjugation

Unconjugated

Descripción general

Lampalizumab (anti-Complement Factor D) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab (anti-Complement Factor D) binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab (anti-Complement Factor D) can be used for age-related macular degeneration (AMD) research.

Specifications

Product Name

Lampalizumab (anti-Complement Factor D) - Anticuerpo primario, specific to CFD, >95%, Human IgG1, Antibody of complement factor D

Sinónimos

Adipsin antibody | Adipsin/complement factor D antibody | Adn antibody | C3 convertase activator antibody | CFAD_HUMAN antibody | CFD antibody | Complement factor D antibody | complement factor D preproprotein antibody | D component of complement antibody

Especificaciones y pureza

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Especies hospedadoras

Humano

Especificidad

CFD

Conjugación

Unconjugated

Grado

Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated

Tipo de acción

INHIBITOR

Mecanismo de acción

Antibody of complement factor D

Isotipo

Human IgG1

Tipo de cadena ligera

kappa

SDS-PAGE

25.7 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 180.0 kDa, under non-reducing conditions.

Método de purificación

Protein A purified

Pureza

>95%

Concentración

See COA

CAS

1278466-20-8

Almacenamiento y envío

Forma

Liquid

Condiciones de almacenamiento de almacenamiento

Store at -80°C,Avoid repeated freezing and thawing

Enviado en

Dry ice packs + Cold packs

Estabilidad y almacenamiento

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imágenes

SEC: Lampalizumab (anti-Complement Factor D) (Ab175571)

Lampalizumab (anti-Complement Factor D) (Ab175571) - SEC
The purity of Lampalizumab (anti-Complement Factor D) (Ab175571) is more than 95% verified by HPLC.

Objetivos asociados (humanos)

CFD Tchem Complement factor D (0 Activities)

Discover Target: CFD

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de acción

Preguntas frecuentes

What does Animal Free mean?

Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1278466-20-8.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Lampalizumab (anti-Complement Factor D)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.