(±)12-HEPE - ≥98%, A solution in ethanol , CAS No.81187-21-5

CAS: 81187-21-5 Cat. No.: H345165 Formule: C20H30O3 Poids moléculaire: 318.45
DISPONIBLE À COMMANDE
GRADE & PURITY ≥98% A solution in ethanol
Synonyms
12-Hydroxyeicosapentaenoic acid | Metocryst | 12-Hydroxy-5,8,10,14,17-eicosapentaenoic acid | Q27140043 | SCHEMBL12970718 | 12-hydroxy-5Z,8Z,10E,14Z,17Z-icosapentaenoic acid | SR-01000946901-1 | (5Z,8Z,10E,14Z,17Z)-12-hydroxyeicosa-5,8,10,14,17-pentaenoic
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
Allemagne (EU)
USA*
Price
Qty
25μg
H345165-25μg
—
1 En stock
411,22€
50μg
H345165-50μg
Sur commande · 8–12 semaines
675,88€
100μg
H345165-100μg
Sur commande · 8–12 semaines
1 338,83€
250μg
H345165-250μg
Sur commande · 8–12 semaines
3 038,74€
Enter a quantity for the sizes you want to add.
🧪
Why this grade

≥98%, A solution in ethanol for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Vue d’ensemble

(±)12-HEPE Produced by non-enzymatic oxidation of EPA, where it contains a racemic mixture. The biological activity is likely mediated by one of the individual isomers, most commonly the 12(S) isomer in mammalian systems. 12-HEPE inhibits platelet aggregation with the same potency as 12-HETE, exhibiting IC50 values of 24 and 25 μM, respectively. These compounds are also equipotent as inhibitors of U46619-induced contraction of rat aorta (IC50s = 8.6-8.8 μM).


application:

(+/-)12-HEPE is a compound which inhibits platelet aggregation.

Specifications

Synonymes
12-Hydroxyeicosapentaenoic acid | Metocryst | 12-Hydroxy-5,8,10,14,17-eicosapentaenoic acid | Q27140043 | SCHEMBL12970718 | 12-hydroxy-5Z,8Z,10E,14Z,17Z-icosapentaenoic acid | SR-01000946901-1 | (5Z,8Z,10E,14Z,17Z)-12-hydroxyeicosa-5,8,10,14,17-pentaenoic
Spécifications et pureté
≥98%, A solution in ethanol
Conditions de stockage de stockage
Store at -20°C
Expédié en
Ice chest + Ice pads
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Pureté
≥98%
Noms et identifiants
Pubchem Sid
Sourires canoniques
CCC=CCC=CCC(C=CC=CCC=CCCCC(=O)O)O
IUPAC Name
(5Z,8Z,10E,14Z,17Z)-12-hydroxyicosa-5,8,10,14,17-pentaenoic acid
InChIKey
MCRJLMXYVFDXLS-QGQBRVLBSA-N
INCHI
1S/C20H30O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h3-4,7-11,13-14,17,19,21H,2,5-6,12,15-16,18H2,1H3,(H,22,23)/b4-3-,9-7-,11-8-,13-10-,17-14+
Isomères SMILES
CC/C=C\C/C=C\CC(/C=C/C=C\C/C=C\CCCC(=O)O)O
Poids moléculaire
318.45
Reaxy-Rn
29757819
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29757819&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClasseFatty Acyls
SubclassEicosanoids
Intermediate Tree Nodes Not available
Direct ParentHydroxyeicosapentaenoic acids
Alternative Parents Long-chain fatty acids  Hydroxy fatty acids  Unsaturated fatty acids  Secondary alcohols  Monocarboxylic acids and derivatives  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Hydroxyeicosapentaenoic acid - Long-chain fatty acid - Hydroxy fatty acid - Fatty acid - Unsaturated fatty acid - Secondary alcohol - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxide - Organic oxygen compound - Alcohol - Hydrocarbon derivative - Carbonyl group - Organooxygen compound - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as hydroxyeicosapentaenoic acids. These are eicosanoic acids with an attached hydroxyl group and five CC double bonds.
External Descriptors Hydroxy/hydroperoxyeicosapentaenoic acids
Structure 3D
Modèle de structure chimique interactif





Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateArticle
K2212317Certificate of AnalysisJun 28, 2022 H345165
K2212419Certificate of AnalysisJun 28, 2022 H345165
H2202353Certificate of AnalysisJun 28, 2022 H345165
I2201530Certificate of AnalysisJun 28, 2022 H345165
Propriétés chimiques et physiques
Point d'ébullition (°C)78° C
Poids moléculaire318.400 g/mol
XLogP34.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count13
Exact Mass318.219 Da
Monoisotopic Mass318.219 Da
Topological Polar Surface Area57.500 Ų
Heavy Atom Count23
Formal Charge0
Complexity428.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count5
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds5
Covalently-Bonded Unit Count1
Calculateurs de solution
Avis

Avis des clients

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.