Antibody-Drug Conjugate (ADC) Manufacturing

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  1. DBCO-PEG4-GGFG-Exatecan
    CAS: 2694856-51-2 Formula: C72H79FN10O17 Molecular Weight: 1375.45
    Out of Stock Item #: D646155
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    SMILES
    O=C1OCC2=C(C=C(C3=NC4=CC(F)=C(C)C(CC[C@@H]5NC(COCNC(CNC([C@H](CC6=CC=CC=C6)NC(CNC(CNC(CCOCCOCCOCCOCCNC(CCC(N7C8=CC=CC=C8C#CC9=CC=CC=C9C7)=O)=O)=O)=O)=show more
  2. Duocarmycin Analog
    CAS: 372954-15-9 PubChem CID: 101150096 Formula: C34H31ClN4O5 Molecular Weight: 611.09
    Out of Stock Item #: D646181
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    IUPAC Name
    tert-butyl N-[4-[[2-[(1S)-1-(chloromethyl)-5-hydroxy-1,2-dihydrobenzo[e]indole-3-carbonyl]-1H-indol-5-yl]carbamoyl]phenyl]carbamate
    SMILES
    CC(C)(C)OC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC3=C(C=C2)NC(=C3)C(=O)N4CC(C5=C4C=C(C6=CC=CC=C65)O)CCl
    InChIKey
    JPKOARKDKWYROQ-OAQYLSRUSA-N
    InChI
    1S/C34H31ClN4O5/c1-34(2,3)44-33(43)37-22-10-8-19(9-11-22)31(41)36-23-12-13-26-20(14-23)15-27(38-26)32(42)39-18-21(17-35)30-25-7-5-4-6-24(25)29(40)16-2show more
  3. MC-DM1
    CAS: 1375089-56-7 PubChem CID: 155819513 Formula: C42H55ClN4O12 Molecular Weight: 843.36
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M646242
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    IUPAC Name
    [(1S,2R,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.0show more
    SMILES
    CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCCCCN5C(=O)C=CC5=O)C)C)OC)(NC(=O)O2)O
    InChIKey
    UGBPANNIQRLRII-MYFUOFFMSA-N
    InChI
    1S/C42H55ClN4O12/c1-24-13-12-14-31(56-8)42(54)23-30(57-40(53)44-42)25(2)38-41(4,59-38)32(22-36(51)46(6)28-20-27(19-24)21-29(55-7)37(28)43)58-39(52)26(show more
  4. Tesirine
    CAS: 1595275-62-9 PubChem CID: 73672523 Formula: C75H101N9O23 Molecular Weight: 1496.65
    Out of Stock Item #: T646379
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    SMILES
    CC1=CN2[C@@H](C1)C=NC3=CC(=C(C=C3C2=O)OC)OCCCCCOC4=C(C=C5C(=C4)N([C@H]([C@@H]6CC(=CN6C5=O)C)O)C(=O)OCC7=CC=C(C=C7)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=show more
  5. Mal-PEG4-VC-PAB-DMEA-PNU-159682
    CAS: 2259318-52-8 Formula: C74H98N10O27 Molecular Weight: 1559.62
    Out of Stock Item #: M646673
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    SMILES
    C[C@H]1[C@]2([H])[C@](N3[C@]([C@H](OCC3)OC)([H])O2)([H])C[C@](O1)([H])O[C@@H]4C5=C(C[C@](C(COC(N(C)CCN(C)C(OCC6=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)show more
  6. Bi-Mc-VC-PAB-MMAE
    CAS: 1620837-70-8 Formula: C71H104N12O18 Molecular Weight: 1413.66
    Out of Stock Item #: B646595
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    Technical Identifiers
    SMILES
    O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)Nshow more
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