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Drug-Linker Conjugates (DLCs)

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  1. Lys-SMCC-DM1 - ≥98% CAS No(1281816-04-3) by Aladdin Scientific
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    Lys-SMCC-DM1
    CAS: 1281816-04-3 PubChem CID: 71587969 Formula: C53H75ClN6O15S Molecular Weight: 1103.71
    ≥98%
    Out of Stock Item #: L353974
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    Technical Identifiers
    IUPAC Name
    (2S)-2-amino-6-[[4-[[3-[3-[[(2S)-1-[[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-show more
    SMILES
    CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCSC5CC(=O)N(C5=O)CC6CCC(CC6)C(=O)NCCCCC(C(=O)O)N)C)C)OC)(NC(=O)O2)O
    InChIKey
    UBRZDBDIKWWPEN-YCPOLOASSA-N
    InChI
    1S/C53H75ClN6O15S/c1-29-12-11-14-40(72-8)53(70)27-38(73-51(69)57-53)30(2)46-52(4,75-46)41(26-43(62)59(6)36-23-33(22-29)24-37(71-7)45(36)54)74-50(68)31show more
    Synonyms
    Lysine-emtansine | AC-36377 | LYSINE-N.EPSILON.-MCC-DM1 | A-MCC-DM1Lys-N | 6E9CC1P9UA | LYSINE-MCC-DM1 | (Rac)-Lys-SM...
  2. Amino-PEG3-C2-acid
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    Amino-PEG3-C2-acid
    CAS: 784105-33-5 Formula: C9H19NO5 Molecular Weight: 221.25
    ≥98%
    In Stock Item #: A122169
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    Technical Identifiers
    IUPAC Name
    3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoic acid
    SMILES
    C(COCCOCCOCCN)C(=O)O
    InChIKey
    XUQZKSCQPMNDEY-UHFFFAOYSA-N
    InChI
    1S/C9H19NO5/c10-2-4-14-6-8-15-7-5-13-3-1-9(11)12/h1-8,10H2,(H,11,12)
    Synonyms
    Amino-PEG3-C2-acid | 3-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]propanoic acid | H2N-PEG3-CH2CH2COOH | alpha-aMine-oMega-pr...
  3. Vc-MMAD - ≥97% CAS No(1401963-17-4) by Aladdin Scientific
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    Vc-MMAD
    CAS: 1401963-17-4 PubChem CID: 78357803 Formula: C70H104N12O14S Molecular Weight: 1369.71
    Solid ≥97%
    In Stock Item #: V125316
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    Technical Identifiers
    IUPAC Name
    [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-show more
    SMILES
    CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)OCC4=CC=C(C=C4)NC(=O)C(CCCNC(=O)N)NC(=O)C(C(show more
    InChIKey
    GRBICHHPFYWKKI-BDVWXETGSA-N
    InChI
    1S/C70H104N12O14S/c1-14-45(8)61(53(94-12)40-57(86)81-37-22-26-52(81)62(95-13)46(9)63(87)76-51(67-72-35-38-97-67)39-47-23-17-15-18-24-47)79(10)68(91)59show more
  4. VcMMAE
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    VcMMAE
    CAS: 646502-53-6 PubChem CID: 46944733 Formula: C68H105N11O15 Molecular Weight: 1316.63
    ≥98%
    In Stock Item #: V125591
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    Technical Identifiers
    IUPAC Name
    [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-show more
    SMILES
    CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)C(CCCNC(=O)N)NC(=O)C(C(C)C)Nshow more
    InChIKey
    NLMBVBUNULOTNS-HOKPPMCLSA-N
    InChI
    1S/C68H105N11O15/c1-15-43(8)59(51(92-13)38-55(83)78-37-23-27-50(78)61(93-14)44(9)62(85)71-45(10)60(84)47-24-18-16-19-25-47)76(11)66(89)57(41(4)5)75-65show more
    Synonyms
    A14362 | Maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl monomethylauristatin E | s6661 | VEDOTIN PARENT ...
  5. DOXO-EMCH
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    DOXO-EMCH
    CAS: 151038-96-9 Formula: C37H42N4O13 Molecular Weight: 750.75
    Out of Stock Item #: D124959
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    Technical Identifiers
    IUPAC Name
    N-[(E)-[1-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]amino]-show more
    SMILES
    CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=NNC(=O)CCCCCN6C(=O)C=CC6=O)CO)O)N)O
    InChIKey
    OBMJQRLIQQTJLR-JRZNSJKLSA-N
    InChI
    1S/C37H42N4O13/c1-17-32(46)20(38)13-27(53-17)54-22-15-37(51,23(16-42)39-40-24(43)9-4-3-5-12-41-25(44)10-11-26(41)45)14-19-29(22)36(50)31-30(34(19)48)3show more
    Synonyms
    2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid (1-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3...
  6. Mc-MMAD
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    Mc-MMAD
    CAS: 1401963-15-2 PubChem CID: 78357802 Formula: C51H77N7O9S Molecular Weight: 964.26
    ≥96%
    In Stock Item #: M125686
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    Technical Identifiers
    IUPAC Name
    6-(2,5-dioxopyrrol-1-yl)-N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)eshow more
    SMILES
    CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)CCCCCN4C(=O)C=CC4=O
    InChIKey
    OZUQLKHIIRUJRZ-PGBUMTRMSA-N
    InChI
    1S/C51H77N7O9S/c1-12-34(6)46(56(9)51(65)44(32(2)3)54-49(64)45(33(4)5)55(8)40(59)23-17-14-18-27-58-41(60)24-25-42(58)61)39(66-10)31-43(62)57-28-19-22-3show more
  7. CL1-SN38
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    CL1-SN38
    CAS: 1279680-68-0 PubChem CID: 89983570 Formula: C73H97N11O22 Molecular Weight: 1480.61
    ≥97%
    In Stock Item #: C412664
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    Technical Identifiers
    IUPAC Name
    [4-[[(2S)-6-amino-2-[[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[4-[[[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]amino]methyl]triazol-1-yl]ethoxy]ethoxshow more
    SMILES
    CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)OC(=O)OCC5=CC=C(C=C5)NC(=O)C(CCCCN)NC(=O)COCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN6C=C(N=N6)CNC(=O)C7CCC(CC7)CN8C(=O)Cshow more
    InChIKey
    CMVRBCDBISKHME-URBSQPMJSA-N
    InChI
    1S/C73H97N11O22/c1-3-55-56-39-54(85)16-17-60(56)79-67-57(55)44-83-62(67)40-59-58(70(83)92)46-104-71(93)73(59,4-2)106-72(94)105-45-50-10-14-52(15-11-50show more
    Synonyms
    CL2A-SN-38
  8. Fmoc-Val-Cit-PAB-MMAE
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    Fmoc-Val-Cit-PAB-MMAE
    CAS: 1350456-56-2 PubChem CID: 118986648 Formula: C73H104N10O14 Molecular Weight: 1345.67
    ≥98%
    In Stock Item #: F412983
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    Technical Identifiers
    IUPAC Name
    [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-show more
    SMILES
    CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)C(CCCNC(=O)N)NC(=O)C(C(C)C)Nshow more
    InChIKey
    RHQGFVOXIOMBMC-UUMMFNFXSA-N
    InChI
    1S/C73H104N10O14/c1-15-45(8)63(58(94-13)39-59(84)83-38-24-32-57(83)65(95-14)46(9)66(86)76-47(10)64(85)49-25-17-16-18-26-49)81(11)70(90)61(43(4)5)79-69show more
  9. MC-DOXHZN hydrochloride
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    MC-DOXHZN hydrochloride
    CAS: 480998-12-7 PubChem CID: 10056071 Formula: C37H43ClN4O13 Molecular Weight: 787.2
    Out of Stock Item #: M412496
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    Technical Identifiers
    IUPAC Name
    N-[(E)-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydshow more
    SMILES
    CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=NNC(=O)CCCCCN6C(=O)C=CC6=O)CO)O)N)O.Cl
    InChIKey
    NGKHWQPYPXRQTM-UKFSEGPMSA-N
    InChI
    1S/C37H42N4O13.ClH/c1-17-32(46)20(38)13-27(53-17)54-22-15-37(51,23(16-42)39-40-24(43)9-4-3-5-12-41-25(44)10-11-26(41)45)14-19-29(22)36(50)31-30(34(19)show more
    Synonyms
    INNO206 HCl | AC-36645 | ALDOXORUBICIN HYDROCHLORIDE [WHO-DD] | S098K6HGD9 | SCHEMBL16766915 | Aldoxorubicin Hydrochl...
  10. SMCC-DM1
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    SMCC-DM1
    CAS: 1228105-51-8 PubChem CID: 92131096 Formula: C51H66ClN5O16S Molecular Weight: 1072.61
    ≥95%
    In Stock Item #: S412843
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (2,5-dioxopyrrolidin-1-yl) 4-[[3-[3-[[(2S)-1-[[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4show more
    SMILES
    CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCSC5CC(=O)N(C5=O)CC6CCC(CC6)C(=O)ON7C(=O)CCC7=O)C)C)OC)(NC(=O)O2)O
    InChIKey
    IADUWZMNTKHTIN-MLSWMBHTSA-N
    InChI
    1S/C51H66ClN5O16S/c1-27-10-9-11-37(69-8)51(67)25-35(70-49(66)53-51)28(2)45-50(4,72-45)38(24-42(61)55(6)33-21-31(20-27)22-34(68-7)44(33)52)71-47(64)29(show more
    Synonyms
    DM1-SMCC
  11. Azido-PEG4-Val-Cit-PAB-MMAE
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    Azido-PEG4-Val-Cit-PAB-MMAE
    CAS: 1869126-64-6 PubChem CID: 162642418 Formula: C69H113N13O17 Molecular Weight: 1396.71
    ≥98%
    Out of Stock Item #: A597241
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    [4-[[(2S)-2-[[(2S)-2-[3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanoylamino]-3-methylbutanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]phenyl]show more
    SMILES
    CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)C(CCCNC(=O)N)NC(=O)C(C(C)C)Nshow more
    InChIKey
    PDBSIBYOBPJSRL-SFLKBQQHSA-N
    InChI
    1S/C69H113N13O17/c1-15-46(8)60(54(93-13)41-56(84)82-32-20-24-53(82)62(94-14)47(9)63(86)74-48(10)61(85)50-21-17-16-18-22-50)80(11)67(90)58(44(4)5)78-66show more
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