ADC Cytotoxin

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  1. S-Me-DM1
    CAS: 912569-84-7 PubChem CID: 154705356 Formula: C36H50ClN3O10S Molecular Weight: 752.31
    Out of Stock Item #: S276125
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    IUPAC Name
    [(1S,2R,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.0show more
    SMILES
    CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCSC)C)C)OC)(NC(=O)O2)O
    InChIKey
    PLYHSTGTQYPYMT-UDXCHANISA-N
    InChI
    1S/C36H50ClN3O10S/c1-20-11-10-12-27(47-8)36(45)19-26(48-34(44)38-36)21(2)32-35(4,50-32)28(49-33(43)22(3)39(5)29(41)13-14-51-9)18-30(42)40(6)24-16-23(1show more
    Synonyms
    N2'-Deacetyl-N2'-(3-thiomethyl-1-oxopropyl)-maytansine
  2. beta-Amanitin
    CAS: 21150-22-1 Formula: C39H53N9O15S Molecular Weight: 919.95
    In Stock Item #: A275546
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    IUPAC Name
    2-[34-butan-2-yl-13-(3,4-dihydroxybutan-2-yl)-8,22-dihydroxy-2,5,11,14,27,30,33,36,39-nonaoxo-27λ4-thia-3,6,12,15,25,29,32,35,38-nonazapentacyclo[14.show more
    SMILES
    CCC(C)C1C(=O)NCC(=O)NC2CS(=O)C3=C(CC(C(=O)NCC(=O)N1)NC(=O)C(NC(=O)C4CC(CN4C(=O)C(NC2=O)CC(=O)O)O)C(C)C(CO)O)C5=C(N3)C=C(C=C5)O
    InChIKey
    IEQCUEXVAPAFMQ-UHFFFAOYSA-N
    InChI
    1S/C39H53N9O15S/c1-4-16(2)31-36(60)41-11-28(53)42-25-15-64(63)38-21(20-6-5-18(50)7-22(20)45-38)9-23(33(57)40-12-29(54)46-31)43-37(61)32(17(3)27(52)14-show more
    Synonyms
    1-L-aspartic acid-α-amanitin
  3. Luisol A
    CAS: 225110-59-8 PubChem CID: 10782062 Formula: C16H18O7 Molecular Weight: 322.31
    Out of Stock Item #: L276072
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    IUPAC Name
    (1S,2R,9S,10R,11S,13R)-2,7,9,10-tetrahydroxy-11-methyl-12,16-dioxatetracyclo[11.3.1.01,10.03,8]heptadeca-3(8),4,6-trien-15-one
    SMILES
    CC1C2(C(C3=C(C=CC=C3O)C(C24CC(O1)CC(=O)O4)O)O)O
    InChIKey
    YAYLZJMYAWCSFK-MAHXAKIKSA-N
    InChI
    1S/C16H18O7/c1-7-16(21)14(20)12-9(3-2-4-10(12)17)13(19)15(16)6-8(22-7)5-11(18)23-15/h2-4,7-8,13-14,17,19-21H,5-6H2,1H3/t7-,8-,13+,14-,15-,16-/m0/s1
    Synonyms
    DTXSID601100859 | rel-(-)-(4R,6S,6aR,7S,12R,12aS)-3,4,6,6a,7,12-Hexahydro-6a,7,8,12-tetrahydroxy-6-methyl-4,12a-metha...
  4. MMAF
    CAS: 745017-94-1 Formula: C39H65N5O8 Molecular Weight: 731.96
    In Stock Item #: M395755
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    IUPAC Name
    (2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]show more
    SMILES
    CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C(=O)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC
    InChIKey
    MFRNYXJJRJQHNW-DEMKXPNLSA-N
    InChI
    1S/C39H65N5O8/c1-12-25(6)34(43(9)38(48)33(24(4)5)42-37(47)32(40-8)23(2)3)30(51-10)22-31(45)44-20-16-19-29(44)35(52-11)26(7)36(46)41-28(39(49)50)21-27-show more
    Synonyms
    MMAF | (2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl...
  5. Rebeccamycin
    CAS: 93908-02-2 PubChem CID: 73110 Formula: C27H21Cl2N3O7 Molecular Weight: 570.38
    Out of Stock Item #: R276440
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    IUPAC Name
    5,21-dichloro-3-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-show more
    SMILES
    COC1C(OC(C(C1O)O)N2C3=C(C=CC=C3Cl)C4=C5C(=C6C7=C(C(=CC=C7)Cl)NC6=C42)C(=O)NC5=O)CO
    InChIKey
    QEHOIJJIZXRMAN-QZQSLCQPSA-N
    InChI
    1S/C27H21Cl2N3O7/c1-38-24-13(8-33)39-27(23(35)22(24)34)32-20-10(5-3-7-12(20)29)15-17-16(25(36)31-26(17)37)14-9-4-2-6-11(28)18(9)30-19(14)21(15)32/h2-7show more
    Synonyms
    HY-19825 | 1,11-dichloro-12-(3,4-dihydroxy-6-hydroxymethyl-5-methoxytetrahydro-2H-2-pyranyl)-6,7,12,13-tetrahydro-5H-...
  6. MMAD
    CAS: 203849-91-6 PubChem CID: 10723894 Formula: C41H66N6O6S Molecular Weight: 771.06
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: M125063
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    IUPAC Name
    (2S)-N-[(2S)-1-[[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-show more
    SMILES
    CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC
    InChIKey
    BLUGYPPOFIHFJS-UUFHNPECSA-N
    InChI
    1S/C41H66N6O6S/c1-12-27(6)36(46(9)41(51)35(26(4)5)45-39(50)34(42-8)25(2)3)32(52-10)24-33(48)47-21-16-19-31(47)37(53-11)28(7)38(49)44-30(40-43-20-22-54show more
    Synonyms
    Monomethylauristatin D | Monomethyl Dolastatin 10 | Demethyldolastatin 10
  7. 7-Ethylcamptothecin
    CAS: 78287-27-1 Formula: C22H20N2O4 Molecular Weight: 376.41
    In Stock Item #: E134852
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    IUPAC Name
    (19S)-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
    SMILES
    CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=CC=CC=C51
    InChIKey
    MYQKIWCVEPUPIL-QFIPXVFZSA-N
    InChI
    1S/C22H20N2O4/c1-3-12-13-7-5-6-8-17(13)23-19-14(12)10-24-18(19)9-16-15(20(24)25)11-28-21(26)22(16,27)4-2/h5-9,27H,3-4,10-11H2,1-2H3/t22-/m0/s1
    Synonyms
    3,3,5-Trimethylcyclohexyl hydroxy(phenyl)acetate | 7-ETHYLCAMPTOTHECIN [USP IMPURITY] | Proeptatriene [Italian] | 4,1...
  8. Adriamycin, Inhibitor of DNA topoisomerase II alpha
    CAS: 23214-92-8 EC Number: 245-495-6 PubChem CID: 31703 Formula: C27H29NO11 Molecular Weight: 543.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: A183027
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    IUPAC Name
    (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
    SMILES
    CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O
    InChIKey
    AOJJSUZBOXZQNB-TZSSRYMLSA-N
    InChI
    1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,1show more
    Synonyms
    Adriablastin | hydroxydaunomycin | Hydroxyldaunorubicin | LMPK13050001 | NCI-C01514 | Doxorubicine | NSC-759155 | D03...
  9. INNO-206, DNA topoisomerase II alpha inhibitor
    CAS: 1361644-26-9 Formula: C37H42N4O13 Molecular Weight: 750.75
    Out of Stock Item #: I125675
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    Technical Identifiers
    IUPAC Name
    N-[(E)-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydshow more
    SMILES
    CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=NNC(=O)CCCCCN6C(=O)C=CC6=O)CO)O)N)O
    InChIKey
    OBMJQRLIQQTJLR-USGQOSEYSA-N
    InChI
    1S/C37H42N4O13/c1-17-32(46)20(38)13-27(53-17)54-22-15-37(51,23(16-42)39-40-24(43)9-4-3-5-12-41-25(44)10-11-26(41)45)14-19-29(22)36(50)31-30(34(19)48)3show more
    Synonyms
    AKOS030526452 | 1H-PYRROLE-1-HEXANOIC ACID, 2,5-DIHYDRO-2,5-DIOXO-, (1-(4-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEX...
  10. Mensacarcin
    CAS: 808750-39-2 PubChem CID: 403671 Formula: C21H24O9 Molecular Weight: 420.41
    Out of Stock Item #: M275033
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    IUPAC Name
    (1S,9S,10S,11S,12S,13S,14R)-11,12,14-trihydroxy-7,9-dimethoxy-13-methyl-12-[(2R,3S)-3-methyloxirane-2-carbonyl]-15-oxatetracyclo[8.4.1.01,10.03,8]pentshow more
    SMILES
    CC1C(C23C(=O)C4=C(C(C2(O3)C(C1(C(=O)C5C(O5)C)O)O)OC)C(=CC=C4)OC)O
    InChIKey
    WWNXYRCJJRRWAQ-ALCXHWRFSA-N
    InChI
    1S/C21H24O9/c1-8-14(22)20-15(23)10-6-5-7-11(27-3)12(10)17(28-4)21(20,30-20)18(25)19(8,26)16(24)13-9(2)29-13/h5-9,13-14,17-18,22,25-26H,1-4H3/t8-,9-,13show more
    Synonyms
    (1R,2S,3S,4S,4aS,9aS,10S)-1,3,4-Trihydroxy-5,10-dimethoxy-2-methyl-3-{[(2R,3S)-3-methyloxiran-2-yl]carbonyl}-1,2,3,4-...
  11. Mertansine (DM1 Compound)
    CAS: 139504-50-0 Formula: C35H48ClN3O10S Molecular Weight: 738.29
    Solid ≥98%
    In Stock Item #: M276427
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    Technical Identifiers
    IUPAC Name
    [(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.0show more
    SMILES
    CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCS)C)C)OC)(NC(=O)O2)O
    InChIKey
    ANZJBCHSOXCCRQ-FKUXLPTCSA-N
    InChI
    1S/C35H48ClN3O10S/c1-19-10-9-11-26(46-8)35(44)18-25(47-33(43)37-35)20(2)31-34(4,49-31)27(48-32(42)21(3)38(5)28(40)12-13-50)17-29(41)39(6)23-15-22(14-1show more
    Synonyms
    N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine, L- | CHEBI:82755 | DDZ29HGH0E | Q4515649 | Mertansine (DM1) | m...
  12. Paclitaxel-d5
    CAS: 1129540-33-5 Formula: C47H46D5NO14 Molecular Weight: 858.94
    In Stock Item #: P333298
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    Technical Identifiers
    IUPAC Name
    [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2,3,4,5,6-pentadeuteriobenzoyl)amino]-3-phenylpropanoyl]oxy-show more
    SMILES
    CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
    InChIKey
    RCINICONZNJXQF-JQTCHTAZSA-N
    InChI
    1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33show more
    Synonyms
    Abraxane-d5 | Genaxol-d5 | Genetaxyl-d5 | OncoGel-d5 | Onxal-d5 | Pacliex-d5 | (-)-Paclitaxel-d5 | Taxol-d5 | Yewtaxa...
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