2′,5′-Dideoxyadenosine - Moligand™, ≥98% , CAS No.6698-26-6

CAS: 6698-26-6 Cat. No.: D335356 Formule: C₁₀H₁₃N₅O₂ Poids moléculaire: 235.24

GRADE & PURITY Moligand™, ≥98%

Synonyms

(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-ol | (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-ol' | 2',5'-Dideoxyadenosine - CAS 6698-26-6 | SCHEMBL284737 | (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-methyltetrahydrofuran-3-ol | 2'5'-Dideoxyadenosi

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Vue d’ensemble

2′,5′-Dideoxyadenosine is a cell-permeable inhibitor of adenylate cyclase, a protein involved in cellular signaling and mast cell granule secretion in immunologic response.

Specifications

Synonymes

(2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-ol | (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-ol' | 2',5'-Dideoxyadenosine - CAS 6698-26-6 | SCHEMBL284737 | (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-methyltetrahydrofuran-3-ol | 2'5'-Dideoxyadenosi

Spécifications et pureté

Moligand™, ≥98%

Conditions de stockage de stockage

Protected from light,Store at -20°C,Argon charged

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

INHIBITOR

Pureté

≥98%

Propriétés du produit

• pKa: pKa: 3.82 (Predicted)

Noms et identifiants

• Pubchem Sid: 528755037
• Sourires canoniques: CC1C(CC(O1)N2C=NC3=C(N=CN=C32)N)O
• IUPAC Name: (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-ol
• InChIKey: FFHPXOJTVQDVMO-DSYKOEDSSA-N
• INCHI: 1S/C10H13N5O2/c1-5-6(16)2-7(17-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7,16H,2H2,1H3,(H2,11,12,13)/t5-,6+,7-/m1/s1
• Isomères SMILES: C[C@@H]1[C@H](C[C@@H](O1)N2C=NC3=C(N=CN=C32)N)O
• WGK Allemagne: 3
• Poids moléculaire: 235.24
• Reaxy-Rn: 25642290
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25642290&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Classe 2',5'-dideoxyribonucleosides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Classe: 2',5'-dideoxyribonucleosides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: 2',5'-dideoxyribonucleosides
• Alternative Parents: 6-aminopurines Aminopyrimidines and derivatives N-substituted imidazoles Imidolactams Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary amines Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 2',5'-dideoxyribonucleoside - 6-aminopurine - Imidazopyrimidine - Purine - Aminopyrimidine - N-substituted imidazole - Pyrimidine - Imidolactam - Azole - Imidazole - Heteroaromatic compound - Tetrahydrofuran - Secondary alcohol - Oxacycle - Azacycle - Organoheterocyclic compound - Amine - Primary amine - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Alcohol - Organic nitrogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 2',5'-dideoxyribonucleosides. These are nucleosides characterized by a purine or pyrimidine base, which is N-linked to a 2',5'-dideoxyribose moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

SK-N-SH (1499 Activities)

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Cibles associées (non humaines)

COS-7 (515 Activities)

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PC-12 (7051 Activities)

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Soluble in DMSO (30 mg/mL), water (20 mg/mL) at 50° C, ethanol (10 mg/mL) at 50° C, and methanol (10 mg/mL - clear, colorless solution).
• Indice de réfraction: n20D1.83 (Predicted)
• Point d'ébullition (°C): ~546.96° C at 760 mmHg (Predicted)
• Point de fusion (°C): 176-178° C
• Poids moléculaire: 235.240 g/mol
• XLogP3: -0.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 235.107 Da
• Monoisotopic Mass: 235.107 Da
• Topological Polar Surface Area: 99.100 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 292.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1