2',7'-Dichlorofluorescein - indicator, ≥90% , CAS No.76-54-0

CAS: 76-54-0 Cat. No.: D113554 Formule: C₂₀H₁₀Cl₂O₅ Poids moléculaire: 401.2 Beilstein Registry Number: 58009 Numéro CE: 200-968-6

QUALITÉ & PURETÉ Indicator, ≥90%

Synonyms

Dichloro(R)fluorescein|2',7'-DICHLOROFLUORESCEIN [MI]|FLUORESCEIN-27|Fluorescein 27|Spiro[isobenzofuran-1(3H),9'-[9h]xanthen]-3-one,2',7'-dichloro-3',6'-dihydroxy-|2',7'-Dichlorofluorescein [Fluorescent indicator]|IOQ|2',7'-Dichloro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one|D AND C ORANGE 25|FLUORESCEIN-548|Dichlorofluorescein|2',7'-dichloro-3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one|2',7'-DICHLORO-3',6'-DIHYDROXYSPIRO(ISOBENZOFURAN-1(3H),9'-(9H)XANTHEN)-3-ONE|2',7'-bis(chloranyl)-3',6'-bis(oxidanyl)spiro[2-benzofuran-3,9'-xanthene]-1-one|Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',7'-dichloro-3',6'-dihydroxy-|2',7'-dichloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one|Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 2',7'-dichloro-3',6'-dihydroxy-|FLUORESCEIN 548|2 inverted exclamation mark ,7 inverted exclamation mark -Dichlorofluorescein|2',7'-DICHLORO-3,6-FLUORANDIOL|2',7'-Dichlorofluorescein|2,7-Dichlorofluorescein

Storage

Room temperature

Shipped In

Normal

Vue d’ensemble

for Fluorescent indicator

Spécifications

Synonymes

Dichloro(R)fluorescein | 2',7'-DICHLOROFLUORESCEIN [MI] | FLUORESCEIN-27 | Fluorescein 27 | Spiro[isobenzofuran-1(3H),9'-[9h]xanthen]-3-one,2',7'-dichloro-3',6'-dihydroxy- | 2',7'-Dichlorofluorescein [Fluorescent indicator] | IOQ | 2',7'-Dichloro-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one | D AND C ORANGE 25 | FLUORESCEIN- Afficher plus

Spécifications et pureté

indicator, ≥90%

Mécanismes biochimiques et physiologiques

Intracellular fluorescent label. Zinpyr-1, DCFA, DFCA DA and DCFDA N-succinimidyl ester precursor. Marker for cellular oxidative stress.

Conditions de stockage de stockage

Room temperature

Expédié en

Normal

Grade

Indicateur

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureté

≥90%

Noms et identifiants

Pubchem Sid

488183646

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488183646

Sourires canoniques

C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C=C4OC5=CC(=C(C=C35)Cl)O)O)Cl

IUPAC Name

2',7'-dichloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one

InChIKey

VFNKZQNIXUFLBC-UHFFFAOYSA-N

INCHI

1S/C20H10Cl2O5/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,23-24H

Isomères SMILES

C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C=C4OC5=CC(=C(C=C35)Cl)O)O)Cl

Poids moléculaire

401.2

Beilstein

58009

Reaxy-Rn

58009

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=58009&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Benzopyrans
      • Subclass 1-benzopyrans
        • Level5 Dibenzopyrans
          • Level6 Xanthenes

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Benzopyrans
• Subclass: 1-benzopyrans
• Intermediate Tree Nodes: Dibenzopyrans
• Direct Parent: Xanthenes
• Alternative Parents: Diarylethers Phthalides Benzofuranones Isobenzofurans 1-hydroxy-2-unsubstituted benzenoids Aryl chlorides Lactones Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Organochlorides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Xanthene - Diaryl ether - Benzofuranone - Phthalide - Isobenzofuranone - Isocoumaran - Isobenzofuran - 1-hydroxy-2-unsubstituted benzenoid - Aryl chloride - Benzenoid - Aryl halide - Carboxylic acid ester - Lactone - Oxacycle - Carboxylic acid derivative - Ether - Monocarboxylic acid or derivatives - Organic oxygen compound - Organooxygen compound - Hydrocarbon derivative - Organochloride - Organic oxide - Organohalogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
• External Descriptors: 2-benzofurans

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Soluble in Solution of sodium hydroxide in water; Slightly soluble in Ethanol
• Point d'éclair (°C): 12°C
• Point de fusion (°C): 280°C
• Poids moléculaire: 401.200 g/mol
• XLogP3: 4.700
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 399.991 Da
• Monoisotopic Mass: 399.991 Da
• Topological Polar Surface Area: 76.000 Ų
• Heavy Atom Count: 27
• Formal Charge: 0
• Complexity: 585.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1