2-Deoxystreptamine, Dihydrobromide - ≥97% , CAS No.84107-26-6

CAS: 84107-26-6 Cat. No.: D351531 Formule: C₆H₁₄N₂O₃ · 2HBr Poids moléculaire: 324.01 Numéro CE: 632-607-7

GRADE & PURITY ≥97%

Synonyms

Deoxystreptamine | 2-Deoxy-D-streptamine dihydrobromide | 2-Deoxystreptamine dihydrobromide | Streptamine, 2-deoxy-, dihydrobromide (9CI) | 4t,6t-Diamino-cyclohexan-1r,2t,3c-triol | 2-DOS · 2HBr | Streptamine, 2-deoxy-, hydrobromide (1:2)

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

2-Deoxystreptamine, Dihydrobromide acts as a structural core within the molecular framework of various aminocyclitol antibiotics, providing a foundational scaffold that is essential for the antibacterial activity of these compounds. Its presence is pivotal in the formation of complex molecular structures that interact with bacterial ribosomal RNA, thereby disrupting protein synthesis. This interaction specifically impedes the correct positioning of tRNA on the ribosome, a critical step in the translation process, leading to the inhibition of bacterial growth and proliferation. The mechanism of action of 2-Deoxystreptamine, Dihydrobromide, and its derivatives emphasizes its significance in research focused on understanding the nuances of bacterial resistance and the development of novel antibiotics. By studying this compound, researchers can gain insights into the structural requirements for antibacterial activity, paving the way for the synthesis of new antibiotics with enhanced efficacy against resistant bacterial strains.

Specifications

Synonymes

Deoxystreptamine | 2-Deoxy-D-streptamine dihydrobromide | 2-Deoxystreptamine dihydrobromide | Streptamine, 2-deoxy-, dihydrobromide (9CI) | 4t,6t-Diamino-cyclohexan-1r,2t,3c-triol | 2-DOS · 2HBr | Streptamine, 2-deoxy-, hydrobromide (1:2)

Spécifications et pureté

≥97%

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥97%

Noms et identifiants

• Pubchem Sid: 528757597
• Sourires canoniques: C1C(C(C(C(C1N)O)O)O)N.Br.Br
• IUPAC Name: (1R,3S,4R,6S)-4,6-diaminocyclohexane-1,2,3-triol;dihydrobromide
• InChIKey: FQPOWLZRZNUTOR-IKNHPHTKSA-N
• INCHI: 1S/C6H14N2O3.2BrH/c7-2-1-3(8)5(10)6(11)4(2)9;;/h2-6,9-11H,1,7-8H2;2*1H/t2-,3+,4+,5-,6?
• Isomères SMILES: C1[C@H]([C@@H](C([C@@H]([C@H]1N)O)O)O)N.Br.Br
• CAS alternatif: 2037-48-1（free base）
• Poids moléculaire: 324.01
• Reaxy-Rn: 2205259
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2205259&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Classe Organooxygen compounds
      • Subclass Alcohols and polyols
        • Level5 Cyclic alcohols and derivatives
          • Level6 Cyclitols and derivatives
            • Level7 Aminocyclitols and derivatives
              • Level8 Aminocyclitols

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Classe: Organooxygen compounds
• Subclass: Alcohols and polyols
• Intermediate Tree Nodes: Cyclic alcohols and derivatives - Cyclitols and derivatives - Aminocyclitols and derivatives
• Direct Parent: Aminocyclitols
• Alternative Parents: Cyclohexylamines Cyclohexanols 1,2-aminoalcohols Polyols Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives Hydrobromides
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: Aminocyclitol - Cyclohexylamine - Cyclohexanol - Secondary alcohol - 1,2-aminoalcohol - Polyol - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Hydrobromide - Primary amine - Organonitrogen compound - Primary aliphatic amine - Amine - Aliphatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as aminocyclitols. These are cyclitols with at least one hydroxyl group replace by an amino group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (non humaines)

Pseudomonas aeruginosa (123386 Activities)

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Micrococcus luteus (7463 Activities)

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Staphylococcus aureus (210822 Activities)

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Staphylococcus epidermidis (22802 Activities)

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Escherichia coli (133304 Activities)

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Soluble in Water
• Sensibilité: Moisture sensitive.
• Poids moléculaire: 162.190 g/mol
• XLogP3: -3.200
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 162.1 Da
• Monoisotopic Mass: 162.1 Da
• Topological Polar Surface Area: 113.000 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 130.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1