≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
5'-Deoxythymidine is a research tool for antiviral and anticancer studies. 5'-Deoxythymidine has been employed in studying the entry mechanism into human erythrocytes in comparison with other deoxythymidines. Deoxythymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is employed to synchronize the cells in S phase. As part of one of the 4 nucleotides in DNA, it is a naturally occurring compound that exists in all living organisms and DNA viruses. RNA has uridine (uracil joined to ribose) instead. Uracil is chemically very similar to thymine, the latter being 5-methyluracil. Since thymine nucleotides are precursors of DNA, and not RNA, the prefix "deoxy" is often left out, i.e., deoxythymidine is often just called thymidine.
| pKa | pKa: 9.55 (Predicted) |
|---|
| Pubchem Sid | 504753961 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504753961 |
| Sourires canoniques | CC1C(CC(O1)N2C=C(C(=O)NC2=O)C)O |
| IUPAC Name | 1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione |
| InChIKey | UGUILUGCFSCUKR-GJMOJQLCSA-N |
| INCHI | 1S/C10H14N2O4/c1-5-4-12(10(15)11-9(5)14)8-3-7(13)6(2)16-8/h4,6-8,13H,3H2,1-2H3,(H,11,14,15)/t6-,7+,8-/m1/s1 |
| Isomères SMILES | C[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)C)O |
| WGK Allemagne | 3 |
| Poids moléculaire | 226.23 |
| Reaxy-Rn | 25337436 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25337436&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Nucleosides, nucleotides, and analogues |
| Classe | 2',5'-dideoxyribonucleosides |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | 2',5'-dideoxyribonucleosides |
| Alternative Parents | Pyrimidones Hydropyrimidines Vinylogous amides Tetrahydrofurans Heteroaromatic compounds Ureas Secondary alcohols Lactams Oxacyclic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | 2',5'-dideoxyribonucleoside - Pyrimidone - Hydropyrimidine - Pyrimidine - Heteroaromatic compound - Vinylogous amide - Tetrahydrofuran - Lactam - Secondary alcohol - Urea - Oxacycle - Azacycle - Organoheterocyclic compound - Alcohol - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as 2',5'-dideoxyribonucleosides. These are nucleosides characterized by a purine or pyrimidine base, which is N-linked to a 2',5'-dideoxyribose moiety. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Article |
|---|---|---|---|
 B2301104 | Certificate of Analysis | Jan 12, 2023 | D349614 |
| B2301105 | Certificate of Analysis | Jan 12, 2023 | D349614 |
| B2301106 | Certificate of Analysis | Jan 12, 2023 | D349614 |
| B2301107 | Certificate of Analysis | Jan 12, 2023 | D349614 |
| B2301109 | Certificate of Analysis | Jan 12, 2023 | D349614 |
| B2301110 | Certificate of Analysis | Jan 12, 2023 | D349614 |
| Solubilité | Soluble in water. |
|---|---|
| Indice de réfraction | n20D1.56 (Predicted) |
| Rotation spécifique [α] | α28/D 8.9°, c = 0.6 in water |
| Point d'ébullition (°C) | 486.56° C (Predicted) |
| Point de fusion (°C) | 192-193° C (lit.) |
| Poids moléculaire | 226.230 g/mol |
| XLogP3 | -0.700 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| Exact Mass | 226.095 Da |
| Monoisotopic Mass | 226.095 Da |
| Topological Polar Surface Area | 78.900 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 366.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
