5-Hydroxytryptophol - ≥98% , CAS No.154-02-9

CAS: 154-02-9 Cat. No.: H274750 Formule: C₁₀H₁₁NO₂ Poids moléculaire: 177.2

GRADE & PURITY ≥98%

Synonyms

FT-0670204 | 1H-Indole-3-ethanol, 5-hydroxy- | NSC 84416 | SCHEMBL233744 | 5-Hydroxy Tryptophol | Hydroxytryptophol | UNII-52MNE52QA1 | US10544152, Cpd # 27 | 5-Hydroxy-1H-indole-3-ethanol | AS-37867 | 5-hydroxy-3-(2-hydroxyethyl)indole | 5-hydroxy-3-(2-h

Storage

Protégé de la lumière,Stocker à -20°C,Chargé à l'argon

Shipped In

Glacière + blocs de glace

Vue d’ensemble

Description du produit :

le 5-hydroxytryptophol est un métabolite de la sérotonine chez les mammifères, qui agit comme un marqueur de la consommation aiguë d'alcool.

Application du produit :

Recherche métabolomique

Specifications

Synonymes

FT-0670204 | 1H-Indole-3-ethanol, 5-hydroxy- | NSC 84416 | SCHEMBL233744 | 5-Hydroxy Tryptophol | Hydroxytryptophol | UNII-52MNE52QA1 | US10544152, Cpd # 27 | 5-Hydroxy-1H-indole-3-ethanol | AS-37867 | 5-hydroxy-3-(2-hydroxyethyl)indole | 5-hydroxy-3-(2-h

Spécifications et pureté

≥98%

Mécanismes biochimiques et physiologiques

Analogue structurel de la sérotonine endogène. Métabolite du L-tryptophane. Inhibe de manière compétitive la glucuronidation de la sérotonine et l'UDP-glucuronosyltransférase (les valeurs K i sont respectivement de 291 et 200 μM). Perméable à la barrière

Conditions de stockage de stockage

Protégé de la lumière,Stocker à -20°C,Chargé à l'argon

Expédié en

Glacière + blocs de glace

Note

Dans la mesure du possible, les solutions doivent être préparées et utilisées le même jour. Toutefois, si vous devez préparer des solutions de base à l'avance, nous vous recommandons de les conserver sous forme d'aliquotes dans des flacons hermétiques à -20°C. Ces aliquotes sont généralement utilisables pendant un mois. En général, ces solutions peuvent être utilisées pendant un mois. Avant utilisation, et avant d'ouvrir le flacon, nous vous recommandons de laisser votre produit s'équilibrer à température ambiante pendant au moins 1 heure. Besoin de plus de conseils sur la solubilité, l'utilisation et la manipulation ? Veuillez consulter notre page de questions fréquemment posées (FAQ) pour plus de détails.

Pureté

≥98%

Noms et identifiants

Pubchem Sid

504751786

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504751786

Sourires canoniques

C1=CC2=C(C=C1O)C(=CN2)CCO

IUPAC Name

3-(2-hydroxyethyl)-1H-indol-5-ol

InChIKey

KQROHCSYOGBQGJ-UHFFFAOYSA-N

INCHI

1S/C10H11NO2/c12-4-3-7-6-11-10-2-1-8(13)5-9(7)10/h1-2,5-6,11-13H,3-4H2

Isomères SMILES

C1=CC2=C(C=C1O)C(=CN2)CCO

Poids moléculaire

177.2

Reaxy-Rn

143517

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=143517&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Indoles and derivatives
      • Subclass Hydroxyindoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Indoles and derivatives
• Subclass: Hydroxyindoles
• Intermediate Tree Nodes: Not available
• Direct Parent: Hydroxyindoles
• Alternative Parents: 3-alkylindoles 1-hydroxy-2-unsubstituted benzenoids Substituted pyrroles Heteroaromatic compounds Azacyclic compounds Primary alcohols Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 3-alkylindole - Hydroxyindole - Indole - 1-hydroxy-2-unsubstituted benzenoid - Substituted pyrrole - Benzenoid - Heteroaromatic compound - Pyrrole - Azacycle - Organic oxygen compound - Alcohol - Primary alcohol - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as hydroxyindoles. These are organic compounds containing an indole moiety that carries a hydroxyl group.
• External Descriptors: a small molecule

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Solubilité: Soluble in water to 10 mM and in DMSO to 100 mM
• Sensibilité: light sensitive
• Poids moléculaire: 177.200 g/mol
• XLogP3: 0.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 177.079 Da
• Monoisotopic Mass: 177.079 Da
• Topological Polar Surface Area: 56.300 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 174.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

How should this product be stored?

Store at ?20 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 154-02-9, the molecular formula is C10H11NO2, and the molecular weight is 177.2 g/mol. InChIKey KQROHCSYOGBQGJ-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.