Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
7-Ketocholesterol is an oxidation product of cholesterol , widely present in atherosclerotic plaques, and has a stronger atherogenic effect than cholesterol . 7-Ketocholesterol can inhibit the rate-limiting enzymes involved in bile acid and cholesterol synthesis, such as cholesterol 7α-hydroxylase and HMG-CoA reductase . 7-Ketocholesterol exhibits pro-inflammatory effects both in vivo and in vitro and can induce cell apoptosis ( apoptosis ).
| Isomeric SMILES | C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C(=O)C=C4[C@@]3(CC[C@@H](C4)O)C)C |
|---|---|
| WGK Germany | 3 |
| Molecular Weight | 400.64 |
| Reaxy-Rn | 2063124 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2063124&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| 1. Yueyuan Zhang, Sha Xu, Jianxin Xu, Fuchao Xu, Geng Lu, Jiawei Zhou, Shuangshuang Gu, Jun Wang. (2023) Prognostic value of plasma 7-ketocholesterol in sepsis. CLINICA CHIMICA ACTA, [PMID:37399884] [10.1016/j.cca.2023.117467] |
| 2. Ge Bai, Chuan-Guo Ma, Yu-Yuan Hu, Shu-Jing Guo, Tong Wang. (2023) Chemical conversions of free phytosterols during the bleaching of corn oil. FOOD CHEMISTRY, [PMID:36731234] [10.1016/j.foodchem.2023.135512] |
| 3. SunHongzheng , HanLongsen , GuoYueshuai , AnHuiqing , WangBing , ZhangXiangzheng , LiJiashuo , JiangYingtong , WangYue , SunGuangyi , ZhuShuai , TangShoubin , GeJuan , ChenMinjian , GuoXuejiang , WangQiang. (2024) The global phosphorylation landscape of mouse oocytes during meiotic maturation. EMBO JOURNAL, [PMID:39256562] [10.1038/s44318-024-00222-1] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
