8-Aminoadenine - ≥98%(HPLC) , CAS No.28128-33-8

CAS: 28128-33-8 Cat. No.: A288024 Formule: C₅H₆N₆ Poids moléculaire: 150.14

GRADE & PURITY ≥98%(HPLC)

Synonyms

1H-Purine-6,8-diamine (9CI) | 1H-Purine-6,8-diamine | SCHEMBL42313 | Q88 | NSC21698 | NSC-21698 | A923992 | 7H-purine-6,8-diamine | AKOS025244128 | AKOS024457949 | 8-Aminoadenine | 9H-Purine-6,8-diamine | DTXSID20402507 | Q27464691 | C15483 | AB-323/40464

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Synonymes

1H-Purine-6,8-diamine (9CI) | 1H-Purine-6,8-diamine | SCHEMBL42313 | Q88 | NSC21698 | NSC-21698 | A923992 | 7H-purine-6,8-diamine | AKOS025244128 | AKOS024457949 | 8-Aminoadenine | 9H-Purine-6,8-diamine | DTXSID20402507 | Q27464691 | C15483 | AB-323/40464

Spécifications et pureté

≥98%(HPLC)

Mécanismes biochimiques et physiologiques

Adenine receptor agonist (Ki= 0.0341μM in HEK293 cells expressing an adenine binding site). Displays 190-fold increased potency at the human binding site over the rat adenine receptor (rAde1R) (Ki= 6.51μM).

Conditions de stockage de stockage

Store at 2-8°C

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥98%(HPLC)

Noms et identifiants

• Sourires canoniques: C1=NC(=C2C(=N1)N=C(N2)N)N
• IUPAC Name: 7H-purine-6,8-diamine
• InChIKey: PFUVOLUPRFCPMN-UHFFFAOYSA-N
• INCHI: 1S/C5H6N6/c6-3-2-4(9-1-8-3)11-5(7)10-2/h1H,(H5,6,7,8,9,10,11)
• Isomères SMILES: C1=NC(=C2C(=N1)N=C(N2)N)N
• Poids moléculaire: 150.14
• Reaxy-Rn: 9614
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9614&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Imidazopyrimidines
      • Subclass Purines and purine derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Imidazopyrimidines
• Subclass: Purines and purine derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: 6-aminopurines
• Alternative Parents: Aminopyrimidines and derivatives Imidolactams Aminoimidazoles Heteroaromatic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 6-aminopurine - Aminopyrimidine - Imidolactam - Pyrimidine - Aminoimidazole - Heteroaromatic compound - Imidazole - Azole - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 6-aminopurines. These are purines that carry an amino group at position 6. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Solvent:2eq.HCl, Max Conc. mg/mL: 15.01, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 7.51, Max Conc. mM: 50
• Poids moléculaire: 150.140 g/mol
• XLogP3: -0.600
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 150.065 Da
• Monoisotopic Mass: 150.065 Da
• Topological Polar Surface Area: 107.000 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 150.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 28128-33-8, the molecular formula is C?H?N?, and the molecular weight is 150.14 g/mol. InChIKey PFUVOLUPRFCPMN-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.