AC 1903 - Moligand™, ≥98%(HPLC) , Channel blocker of TRPC5, CAS No.831234-13-0, Channel blocker of TRPC5

CAS: 831234-13-0 Cat. No.: A287610 Formule: C19H17N3O Poids moléculaire: 303.36 Numéro CE: 820-119-9
DISPONIBLE À COMMANDE
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
Synonyms
EX-A4021 | 1-benzyl-N-(furan-2-ylmethyl)-1H-benzimidazol-2-amine | cid_667146 | VU0217898-5 | N-(1-BENZYL-1H-1,3-BENZIMIDAZOL-2-YL)-N-(2-FURYLMETHYL)AMINE | (1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine | SCHEMBL22619593 | BDBM49021 | AC 1903 | D95158 | E
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
Allemagne (EU)
USA*
Price
Qty
5mg
A287610-5mg
—
3 En stock

38,09€

57,18€
Enregistrer 19,09 € (33.38%)
10mg
A287610-10mg
—
3 En stock

55,45€

83,22€
Enregistrer 27,77 € (33.37%)
25mg
A287610-25mg
—
2 En stock

93,63€

140,49€
Enregistrer 46,86 € (33.35%)
50mg
A287610-50mg
—
2 En stock

158,71€

238,54€
Enregistrer 79,83 € (33.47%)
100mg
A287610-100mg
Sur commande · 8–12 semaines

270,65€

406,02€
Enregistrer 135,37 € (33.34%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Vue d’ensemble

AC1903 has been used as a drug candidate in a high-throughput agar colony formation assay to identify its therapeutic efficiency against medulloblastoma.

Specifications

Synonymes
EX-A4021 | 1-benzyl-N-(furan-2-ylmethyl)-1H-benzimidazol-2-amine | cid_667146 | VU0217898-5 | N-(1-BENZYL-1H-1,3-BENZIMIDAZOL-2-YL)-N-(2-FURYLMETHYL)AMINE | (1-benzylbenzimidazol-2-yl)-(2-furfuryl)amine | SCHEMBL22619593 | BDBM49021 | AC 1903 | D95158 | E
Spécifications et pureté
Moligand™, ≥98%(HPLC)
Mécanismes biochimiques et physiologiques
Selective TRPC5 blocker (IC50= 13.6 μM). Also displays weak inhibition at TRPC4 (IC50>100 μM) but not TRPC6. Exhibits no effect against a standard panel of profiling kinases. Blocks TRPC5 channel activity in glomeruli of proteinuric rats. Suppresses sever
Conditions de stockage de stockage
Store at -20°C
Expédié en
Ice chest + Ice pads
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Grade
Moligand™
Type d'action
CHANNEL BLOCKER
Mécanisme d'action
Channel blocker of TRPC5
Pureté
≥98%(HPLC)
Noms et identifiants
Pubchem Sid504759804
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504759804
Sourires canoniquesC1=CC=C(C=C1)CN2C3=CC=CC=C3N=C2NCC4=CC=CO4
IUPAC Name1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine
InChIKeyOECUWHDVQIITIS-UHFFFAOYSA-N
INCHI1S/C19H17N3O/c1-2-7-15(8-3-1)14-22-18-11-5-4-10-17(18)21-19(22)20-13-16-9-6-12-23-16/h1-12H,13-14H2,(H,20,21)
Isomères SMILES C1=CC=C(C=C1)CN2C3=CC=CC=C3N=C2NCC4=CC=CO4
Poids moléculaire 303.36
Reaxy-Rn 32139785
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32139785&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClasseBenzimidazoles
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentBenzimidazoles
Alternative Parents Secondary alkylarylamines  N-substituted imidazoles  Benzene and substituted derivatives  Aminoimidazoles  Heteroaromatic compounds  Furans  Oxacyclic compounds  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Benzimidazole - Secondary aliphatic/aromatic amine - Aminoimidazole - Monocyclic benzene moiety - Benzenoid - N-substituted imidazole - Azole - Heteroaromatic compound - Furan - Imidazole - Oxacycle - Azacycle - Secondary amine - Organic nitrogen compound - Amine - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as benzimidazoles. These are organic compounds containing a benzene ring fused to an imidazole ring (five member ring containing a nitrogen atom, 4 carbon atoms, and two double bonds).
External Descriptors Not available
Structure 3D
Modèle de structure chimique interactif





Cibles associées (humaines)
TRPC5 Tchem Short transient receptor potential channel 5 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRPC5 Tchem Short transient receptor potential channel 5 (300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cibles associées (non humaines)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mécanismes d'action
Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateArticle
C2211327Certificate of AnalysisDec 17, 2024 A287610
C2211328Certificate of AnalysisDec 17, 2024 A287610
C2211329Certificate of AnalysisDec 17, 2024 A287610
C2211330Certificate of AnalysisDec 17, 2024 A287610
C2211331Certificate of AnalysisDec 17, 2024 A287610
Propriétés chimiques et physiques
SolubilitéSolvent:DMSO, Max Conc. mg/mL: 15.17, Max Conc. mM: 50
Poids moléculaire303.400 g/mol
XLogP33.900
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass303.137 Da
Monoisotopic Mass303.137 Da
Topological Polar Surface Area43.000 Ų
Heavy Atom Count23
Formal Charge0
Complexity372.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculateurs de solution
Avis

Avis des clients

Foire aux questions

What is the purity of this product, and how is it determined?
This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 831234-13-0, the molecular formula is C19H17N3O, and the molecular weight is 303.36 g/mol. InChIKey OECUWHDVQIITIS-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.