Acevaltrate - ≥99% , CAS No.25161-41-5

CAS: 25161-41-5 Cat. No.: A649443 Formule: C₂₄H₃₂O₁₀ Poids moléculaire: 480.50 PubChem CID: 65717

QUALITÉ & PURETÉ ≥99%

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Acevaltrate inhibits the Na + / K + -ATPase activity in the rat kidney and brain hemispheres with IC 50 s of 22.8 μM and 42.3 μM, respectively

In Vitro

Acevaltrate differentiallys inhibit the activity of rat P-type ATPases in vitro. 60.7±7.3% inhibition of the rat H + /K + -ATPase is achieved at 100 µM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 22.8±1.1 μM (Na + /K + -ATPase, in rat kidney), 42.3±1.0 μM (Na + /K + -ATPase, in rat brain hemispheres)

Spécifications

Spécifications et pureté

≥99%

Mécanismes biochimiques et physiologiques

Acevaltrate inhibits the Na + / K + -ATPase activity in the rat kidney and brain hemispheres with IC 50 s of 22.8 μM and 42.3 μM, respectively.

Conditions de stockage de stockage

Protected from light,Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Pureté

≥99%

Noms et identifiants

Isomères SMILES

CC(C)CC(=O)O[C@H]1[C@H]2C(=C[C@@H]([C@]23CO3)OC(=O)CC(C)(C)OC(=O)C)C(=CO1)COC(=O)C

PubChem CID

65717

Poids moléculaire

480.50

Cibles associées (humaines)

HCT-8 (3484 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A549 (127892 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: DMSO : 100 mg/mL (208.12 mM; Need ultrasonic)
• Poids moléculaire: 480.500 g/mol
• XLogP3: 0.900
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 13
• Exact Mass: 480.2 Da
• Monoisotopic Mass: 480.2 Da
• Topological Polar Surface Area: 127.000 Ų
• Heavy Atom Count: 34
• Formal Charge: 0
• Complexity: 915.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1