Acridine - ≥98% , DNA disrupting agent, CAS No.260-94-6, DNA disrupting agent

CAS: 260-94-6 Cat. No.: A106024 Formule: C₁₃H₉N Poids moléculaire: 179.22 Beilstein Registry Number: 120200 Numéro CE: 205-971-6

QUALITÉ & PURETÉ ≥98%

Synonyms

10-Azaanthracene|UPCMLD-DP077:001|ACRIDINE|Benzo[b]quinoline|acridine acid|Akridin [Czech]|2,3-Benzoquinoline|ACRIDINE [MI]|Benzoquinolinylidene|2,3,5,6-Dibenzopyridine|9-Azaanthracene|Benzo(b)quinoline|Dibenzo(b,e)pyridine|Coal tar pitch volatiles: acridine|Acridines|Acridine (purified by sublimation)|Akridin|Acrydine|ACRIDINE (1,2,3,4,5,6,7,8,9-D9)|Acridine [UN2713] [Poison]

Storage

Room temperature

Shipped In

FedEx DG Service

Vue d’ensemble

The fluorescence intensity, fluorescence quantum yield, time of decay, and lifetime are dependent upon the solvent. For example, the fluorescence intensity varies from being moderately strong in aqueous solution and very weak in hydrocarbon solvents. Addit

Spécifications

Synonymes

10-Azaanthracene | UPCMLD-DP077:001 | ACRIDINE | Benzo[b]quinoline | acridine acid | Akridin [Czech] | 2,3-Benzoquinoline | ACRIDINE [MI] | Benzoquinolinylidene | 2,3,5,6-Dibenzopyridine | 9-Azaanthracene | Benzo(b)quinoline | Dibenzo(b,e)pyridine | Coal tar pitch volatiles: acridine | Acridines | Acridine (purified by sublimation) | Akri Afficher plus

Spécifications et pureté

≥98%

Mécanismes biochimiques et physiologiques

Nucleic acid phosphate is a small cationic planar dye that mainly binds to RNA and DNA. Used for nucleic acid staining, especially cell cycle determination

Conditions de stockage de stockage

Room temperature

Expédié en

FedEx DG Service

Type d'action

DISRUPTING AGENT

Mécanisme d'action

DNA disrupting agent

Pureté

≥98%

Propriétés du produit

ALogP

3.4

Noms et identifiants

Pubchem Sid

488180942

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488180942

Sourires canoniques

C1=CC=C2C(=C1)C=C3C=CC=CC3=N2

IUPAC Name

acridine

InChIKey

DZBUGLKDJFMEHC-UHFFFAOYSA-N

INCHI

1S/C13H9N/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12/h1-9H

Isomères SMILES

C1=CC=C2C(=C1)C=C3C=CC=CC3=N2

WGK Allemagne

3

RTECS

AR7175000

Numéro ONU

2713

Groupe d'emballage

III

Poids moléculaire

179.22

Beilstein

120200

Reaxy-Rn

120200

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=120200&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Quinolines and derivatives
      • Subclass Benzoquinolines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Quinolines and derivatives
• Subclass: Benzoquinolines
• Intermediate Tree Nodes: Not available
• Direct Parent: Acridines
• Alternative Parents: Pyridines and derivatives Benzenoids Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Acridine - Benzenoid - Pyridine - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as acridines. These are organic compounds containing the acridine moiety, a linear tricyclic heterocycle which consists of two benzene rings joined by a pyridine ring.
• External Descriptors: acridines - polycyclic heteroarene - mancude organic heterotricyclic parent

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

TOP2A Tclin DNA topoisomerase II alpha (6317 Activities)

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ACHE Tclin Acetylcholinesterase (18204 Activities)

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HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)

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GLA Tclin Alpha-galactosidase A (5444 Activities)

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

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A2780 (11979 Activities)

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POLI Tchem DNA polymerase iota (116820 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

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SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)

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Cibles associées (non humaines)

L1210 (27553 Activities)

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Calf thymus DNA (4845 Activities)

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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

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Mapt Microtubule-associated protein tau (6 Activities)

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FTL Ferritin light chain (43324 Activities)

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: Very soluble in Ethanol,Ether,Benzene,Alcohol
• Point d'ébullition (°C): 345-346°C
• Point de fusion (°C): 111°C
• Poids moléculaire: 179.220 g/mol
• XLogP3: 3.400
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 179.073 Da
• Monoisotopic Mass: 179.073 Da
• Topological Polar Surface Area: 12.900 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 181.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1