AH3960 - Moligand™,≥99% , CAS No.862907-48-0

CAS: 862907-48-0 Cat. No.: A650765 Formule: C₁₃H₂₂N₄O₃ Poids moléculaire: 282.34 PubChem CID: 135508376

GRADE & PURITY Moligand™, ≥99%

Synonyms

AH-3960

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

AH3960 is a selective parathyroid hormone 1 receptor (PTHR1) agonist and also an antagonist of wild-type/T877A mutant androgen receptor (AR). AH3960 exhibits pIC50 value against wild-type PTHR1 of 4.03, the IC50 against wild-type AR of 1.5 μM, and the IC50 against T877A mutant AR of 0.35 μM. AH3960 activates the cAMP and calcium signaling pathways. AH3960 inhibits adipocyte differentiation and the expression of adipocyte markers, and promotes early differentiation of osteoblasts. AH3960 is applicable to research related to osteoporosis and prostate cancer.

Specifications

Synonymes

AH-3960

Spécifications et pureté

Moligand™,≥99%

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

AGONIST

Pureté

≥99%

Noms et identifiants

• Sourires canoniques: CCCCN1C(=C(C(=O)N(C1=O)CCCC)C(=N)N)O
• IUPAC Name: 1,3-dibutyl-4-hydroxy-2,6-dioxopyrimidine-5-carboximidamide
• InChIKey: VOYADQIFGGIKAT-UHFFFAOYSA-N
• INCHI: 1S/C13H22N4O3/c1-3-5-7-16-11(18)9(10(14)15)12(19)17(13(16)20)8-6-4-2/h18H,3-8H2,1-2H3,(H3,14,15)
• Isomères SMILES: CCCCN1C(=C(C(=O)N(C1=O)CCCC)C(=N)N)O
• PubChem CID: 135508376
• Termes d'entrée MeSH: 1,3-dibutyl-5-(diaminomethylene)pyrimidine-2,4,6-trione;AH-3960;AH3960;dibutyl-diaminomethylene-pyrimidine-2,4,6-trione
• Poids moléculaire: 282.34

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Diazines
      • Subclass Pyrimidines and pyrimidine derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Diazines
• Subclass: Pyrimidines and pyrimidine derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Hydroxypyrimidines
• Alternative Parents: Pyrimidones Hydropyrimidines Vinylogous amides Vinylogous acids Heteroaromatic compounds Ureas Lactams Carboximidamides Carboxamidines Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Hydroxypyrimidine - Pyrimidone - Hydropyrimidine - Heteroaromatic compound - Vinylogous amide - Vinylogous acid - Urea - Lactam - Azacycle - Carboximidamide - Carboxylic acid amidine - Amidine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as hydroxypyrimidines. These are organic compounds containing a hydroxyl group attached to a pyrimidine ring. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Poids moléculaire: 282.340 g/mol
• XLogP3: 1.500
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 282.169 Da
• Monoisotopic Mass: 282.169 Da
• Topological Polar Surface Area: 111.000 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 445.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Foire aux questions

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 862907-48-0, the molecular formula is C13H22N4O3, and the molecular weight is 282.34 g/mol. InChIKey VOYADQIFGGIKAT-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.