AM 1172 - ≥98%(HPLC) , CAS No.251908-92-6

CAS: 251908-92-6 Cat. No.: A287204 Formule: C₂₇H₃₉NO₂ Poids moléculaire: 409.6 PubChem CID: 10364179

GRADE & PURITY ≥98%(HPLC)

Synonyms

SCHEMBL14105462 | N-arachidonyl 4-hydroxybenzamide | UNII-G5DZB59PZA | AM1172 | AM-1172 | AM2201-d5 | BA168613 | SR-01000946702 | SR-01000946702-1 | AKOS024457594 | 4-hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]benzamide | Benzamide, N-(5Z,8Z,11Z

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

AM1172 is metabolically stable anandamide uptake inhibitor and FAAH inhibitor.

Specifications

Synonymes

SCHEMBL14105462 | N-arachidonyl 4-hydroxybenzamide | UNII-G5DZB59PZA | AM1172 | AM-1172 | AM2201-d5 | BA168613 | SR-01000946702 | SR-01000946702-1 | AKOS024457594 | 4-hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]benzamide | Benzamide, N-(5Z,8Z,11Z

Spécifications et pureté

≥98%(HPLC)

Mécanismes biochimiques et physiologiques

Metabolically stable anandamide uptake inhibitor (IC50= 2.1 - 2.5μM) and fatty acid amide hydrolase (FAAH) inhibitor (Ki= 3.18μM). InhibitsN-arachidonylethanolamine (AEA) accumulation (IC50= 24μM) and hydrolysis (Ki= 3μM), and inhibitsN-palmitoylethanolam

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Pureté

≥98%(HPLC)

Noms et identifiants

• Sourires canoniques: CCCCCC=CCC=CCC=CCC=CCCCCNC(=O)C1=CC=C(C=C1)O
• IUPAC Name: 4-hydroxy-N-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]benzamide
• InChIKey: XCWBOAHOJHPWLA-DOFZRALJSA-N
• INCHI: 1S/C27H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-28-27(30)25-20-22-26(29)23-21-25/h6-7,9-10,12-13,15-16,20-23,29H,2-5,8,11,14,17-19,24H2,1H3,(H,28,30)/b7-6-,10-9-,13-12-,16-15-
• Isomères SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCNC(=O)C1=CC=C(C=C1)O
• PubChem CID: 10364179
• Poids moléculaire: 409.6

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzamides
• Alternative Parents: Benzoyl derivatives 1-hydroxy-2-unsubstituted benzenoids Secondary carboxylic acid amides Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzamide - Benzoyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as benzamides. These are organic compounds containing a carboxamido substituent attached to a benzene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriétés chimiques et physiques

• Solubilité: Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 10(mg/mL))
• Poids moléculaire: 409.600 g/mol
• XLogP3: 7.800
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 16
• Exact Mass: 409.298 Da
• Monoisotopic Mass: 409.298 Da
• Topological Polar Surface Area: 49.300 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 525.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 4
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 4
• Covalently-Bonded Unit Count: 1