Amitriptyline-d6 Hydrochloride - ≥99 atom% D,≥98% , CAS No.203645-63-0

CAS: 203645-63-0 Cat. No.: A357463 Formule: C₂₀H₁₈D₆ClN Poids moléculaire: 319.90 Numéro CE: 846-446-7

GRADE & PURITY ≥99 atom% D,≥98%

Synonyms

3-(5,6-dihydrodibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride | 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine-d6 Hydrochloride

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Vue d’ensemble

Amitriptyline-d6 (hydrochloride) is the deuterium labeled Amitriptyline hydrochloride. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity

Specifications

Synonymes

3-(5,6-dihydrodibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride | 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine-d6 Hydrochloride

Spécifications et pureté

≥99 atom% D,≥98%

Conditions de stockage de stockage

Store at 2-8°C,Protected from light

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥99 atom% D,≥98%

Noms et identifiants

• Pubchem Sid: 528773940
• Sourires canoniques: CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
• IUPAC Name: 3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)-N,N-bis(trideuteriomethyl)propan-1-amine;hydrochloride
• InChIKey: KFYRPLNVJVHZGT-TXHXQZCNSA-N
• INCHI: 1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H/i1D3,2D3
• Isomères SMILES: [2H]C([2H])([2H])N(CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31)C([2H])([2H])[2H].Cl
• CAS alternatif: 549-18-8（Unlabelled ）
• Numéro ONU: 2811
• Groupe d'emballage: III
• Poids moléculaire: 319.90
• Reaxy-Rn: 4164595
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4164595&ln=

Propriétés chimiques et physiques

• Sensibilité: Light sensitive；Moisture sensitive
• Point de fusion (°C): 192-195° C