AP1867-2-(carboxymethoxy) - ≥99% , CAS No.2230613-03-1

CAS: 2230613-03-1 Cat. No.: A648529 Formule: C₃₈H₄₇NO₁₁ Poids moléculaire: 693.78 Numéro CE: 894-476-4 PubChem CID: 133080821

GRADE & PURITY ≥99%

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12 F36V -directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules.

In Vitro

dTAG molecules engage FKBP12 F36V and CRBN. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifications

Spécifications et pureté

≥99%

Mécanismes biochimiques et physiologiques

AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12 F36V -directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules.

Conditions de stockage de stockage

Protected from light,Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Pureté

≥99%

Noms et identifiants

• Sourires canoniques: CCC(C1=CC(=C(C(=C1)OC)OC)OC)C(=O)N2CCCCC2C(=O)OC(CCC3=CC(=C(C=C3)OC)OC)C4=CC=CC=C4OCC(=O)O
• IUPAC Name: 2-[2-[(1R)-3-(3,4-dimethoxyphenyl)-1-[(2S)-1-[(2S)-2-(3,4,5-trimethoxyphenyl)butanoyl]piperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid
• InChIKey: UYXSZUBFOQLRNQ-BTIIJPOSSA-N
• INCHI: 1S/C38H47NO11/c1-7-26(25-21-33(46-4)36(48-6)34(22-25)47-5)37(42)39-19-11-10-13-28(39)38(43)50-30(27-12-8-9-14-29(27)49-23-35(40)41)17-15-24-16-18-31(44-2)32(20-24)45-3/h8-9,12,14,16,18,20-22,26,28,30H,7,10-11,13,15,17,19,23H2,1-6H3,(H,40,41)/t26-,28-,30+/m0/s1
• PubChem CID: 133080821
• Poids moléculaire: 693.78

Propriétés chimiques et physiques

• Solubilité: DMSO : 180 mg/mL (259.45 mM; Need ultrasonic)
• Poids moléculaire: 693.800 g/mol
• XLogP3: 6.300
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 18
• Exact Mass: 693.315 Da
• Monoisotopic Mass: 693.315 Da
• Topological Polar Surface Area: 139.000 Ų
• Heavy Atom Count: 50
• Formal Charge: 0
• Complexity: 1050.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1