The store will not work correctly when cookies are disabled.
Javascript est désactivé dans votre navigateur. Pour une meilleure expérience sur notre site, assurez-vous d’activer JavaScript dans votre navigateur.
· · COA & SDS disponible pour chaque produit · Expédition le jour même sur les articles en stock AS 2444697 - ≥98% , CAS No.1287665-60-4
Synonyms
N-[3-Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide hydrochloride
Storage
Store at 2-8°C,Desiccated
🧪
Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
🌡
Storage & shipping Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
📋
Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
📚
Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonymes
N-[3-Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide hydrochloride
Spécifications et pureté
≥98%
Mécanismes biochimiques et physiologiques
Potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC50= 21 nM). Displays 30-fold selectivity for IRAK4 over IRAK1. Inhibits LPS-induced TNF-αand IL-6 production in PBMCsin vitro. Renoprotective and anti-inflammatory in a r
Conditions de stockage de stockage
Store at 2-8°C,Desiccated
Expédié en
Wet ice
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Noms et identifiants Pubchem Sid 508810314 Sourires canoniques CC1=NC=CC(=C1)C2=NC(=CO2)C(=O)NC3=CN(N=C3C(=O)N)C4CCOCC4.Cl IUPAC Name N-[3-carbamoyl-1-(oxan-4-yl)pyrazol-4-yl]-2-(2-methylpyridin-4-yl)-1,3-oxazole-4-carboxamide;hydrochloride InChIKey FGNHLIIFEDYNFZ-UHFFFAOYSA-N INCHI 1S/C19H20N6O4.ClH/c1-11-8-12(2-5-21-11)19-23-15(10-29-19)18(27)22-14-9-25(24-16(14)17(20)26)13-3-6-28-7-4-13;/h2,5,8-10,13H,3-4,6-7H2,1H3,(H2,20,26)(H,22,27);1H Isomères SMILES CC1=NC=CC(=C1)C2=NC(=CO2)C(=O)NC3=CN(N=C3C(=O)N)C4CCOCC4.Cl Poids moléculaire 432.86 Reaxy-Rn 26307283 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=26307283&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Classe Carboxylic acids and derivatives Subclass Carboxylic acid derivatives Intermediate Tree Nodes Carboxylic acid amides Direct Parent 2-heteroaryl carboxamides Alternative Parents Pyrazole-5-carboxamides 2,4-disubstituted oxazoles Methylpyridines Oxanes Vinylogous amides Heteroaromatic compounds Secondary carboxylic acid amides Primary carboxylic acid amides Oxacyclic compounds Azacyclic compounds Dialkyl ethers Hydrocarbon derivatives Hydrochlorides Organic oxides Organonitrogen compounds Organopnictogen compounds Molecular Framework Aromatic heteromonocyclic compounds Substituents 2-heteroaryl carboxamide - Pyrazole-5-carboxamide - 2,4-disubstituted 1,3-oxazole - Methylpyridine - Pyridine - Oxane - Pyrazole - Azole - Vinylogous amide - Oxazole - Heteroaromatic compound - Secondary carboxylic acid amide - Primary carboxylic acid amide - Organoheterocyclic compound - Azacycle - Oxacycle - Dialkyl ether - Ether - Organic nitrogen compound - Hydrochloride - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as 2-heteroaryl carboxamides. These are compounds containing a heteroaromatic ring that carries a carboxamide group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Structure 3D Cibles associées (humaines) Cibles associées (non humaines) Mécanismes d'action Certificats (CoA, COO, BSE/TSE et tableau d'analyse) Propriétés chimiques et physiques Solubilité Solvent:DMSO, Max Conc. mg/mL: 8.66, Max Conc. mM: 20 with gentle warming Sensibilité Moisture sensitive Poids moléculaire 432.900 g/mol XLogP3 Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 7 Rotatable Bond Count 5 Exact Mass 432.131 Da Monoisotopic Mass 432.131 Da Topological Polar Surface Area 138.000 Ų Heavy Atom Count 30 Formal Charge 0 Complexity 601.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
FAQ et articles Calculateurs de solution Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator Avis
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our
Cookie Policy. Paramètres Accepter tout Refuser
Shall we send you a message when we have discounts available?
Remind me later Autoriser
Thank you! Please check your email inbox to confirm.
Oops! Notifications are disabled.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.
C2421129