GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.10mM in DMSO
Moligand™,10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Vue d’ensemble
AZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pK i values of 7.93 and 9.06 for human CB1R and CB2R , respectively. AZD1940 shows a robust analgesia action
In Vitro
AZD1940 binds with high affinity to human, rat and mouse CB1 and CB2 receptors and displays full agonism at both receptors in all three species . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
When given orally to rats, AZD1940 produces a robust analgesia in different models of inflammatory and neuropathic pain. For AZD1940, low brain uptake at analgesic doses has been demonstrated in both rats and primates . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:hCB1-R 7.93 (pKi) hCB2-R 9.06 (pKi)
Specifications
Spécifications et pureté
Moligand™,10mM in DMSO
Mécanismes biochimiques et physiologiques
AZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pK i values of 7.93 and 9.06 for human CB1R and CB2R , respectively. AZD1940 shows a robust analgesia action.
Conditions de stockage de stockage
Store at -80°C
Expédié en
Dry ice packs + Cold packs
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
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