Azlocillin sodium salt - ≥99% , Penicillin-binding protein inhibitor, CAS No.37091-65-9, Penicillin-binding protein inhibitor

CAS: 37091-65-9 Cat. No.: A129398 Formule: C₂₀H₂₂N₅O₆SNa Poids moléculaire: 483.47 Numéro CE: 253-347-7 PubChem CID: 23685176

QUALITÉ & PURETÉ ≥99%

Synonyms

HMS2097F03 | A19406 | SW202561-3 | 4-(4-Methyl-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-thiazol-2-ylamino)-phenyl]-benzamide | Securopen | sodium 2,2-dimethyl-6beta-((2R)-2-(((2-oxoimidazolidin-1-yl)carbonyl)amino)-2-phenylacetamido)penam-3alph

Storage

Store at 2-8°C

Shipped In

Wet ice

Vue d’ensemble

Azlocillin is an acylampicillin with a broad spectrum against bacteria.
Azlocillin is a semisynthetic penicillin and is a potent 1-lactam antibiotic. It is often used against Pseudomonas aeruginosa and has been used to develop novel antibiotic quantitation techniques

Spécifications

Synonymes

HMS2097F03 | A19406 | SW202561-3 | 4-(4-Methyl-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-thiazol-2-ylamino)-phenyl]-benzamide | Securopen | sodium 2,2-dimethyl-6beta-((2R)-2-(((2-oxoimidazolidin-1-yl)carbonyl)amino)-2-phenylacetamido)penam-3alph

Spécifications et pureté

≥99%

Mécanismes biochimiques et physiologiques

Azlocillin inhibits penicillin-binding protein (PBP)-dependent bacterial cell wall synthesis.

Conditions de stockage de stockage

Store at 2-8°C

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Mécanisme d'action

Penicillin-binding protein inhibitor

Pureté

≥99%

Noms et identifiants

Pubchem Sid

488200525

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488200525

Sourires canoniques

CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)NC(=O)N4CCNC4=O)C(=O)[O-])C.[Na+]

IUPAC Name

sodium;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

InChIKey

UVOCNBWUHNCKJM-XFAPPKAWSA-M

INCHI

1S/C20H23N5O6S.Na/c1-20(2)13(17(28)29)25-15(27)12(16(25)32-20)22-14(26)11(10-6-4-3-5-7-10)23-19(31)24-9-8-21-18(24)30;/h3-7,11-13,16H,8-9H2,1-2H3,(H,21,30)(H,22,26)(H,23,31)(H,28,29);/q;+1/p-1/t11-,12-,13+,16-;/m1./s1

Isomères SMILES

CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)NC(=O)N4CCNC4=O)C(=O)[O-])C.[Na+]

WGK Allemagne

3

RTECS

XH9250000

PubChem CID

23685176

Poids moléculaire

483.47

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 N-acyl-alpha amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: N-acyl-alpha amino acids and derivatives
• Alternative Parents: Penams Benzene and substituted derivatives Thiazolidines Tertiary carboxylic acid amides Imidazolines Azetidines Isoureas Azacyclic compounds Thiohemiaminal derivatives Propargyl-type 1,3-dipolar organic compounds Carboximidamides Carboxylic acids Dialkylthioethers Monocarboxylic acids and derivatives Hydrocarbon derivatives Organopnictogen compounds Organic zwitterions Carbonyl compounds Organic oxides Organic sodium salts
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: N-acyl-alpha amino acid or derivatives - Penam - Monocyclic benzene moiety - Benzenoid - Beta-lactam - 2-imidazoline - Tertiary carboxylic acid amide - Thiazolidine - Carboxamide group - Azetidine - Isourea - Lactam - Azacycle - Organic alkali metal salt - Carboximidic acid - Carboximidic acid derivative - Organoheterocyclic compound - Carboxylic acid - Dialkylthioether - Organic 1,3-dipolar compound - Monocarboxylic acid or derivatives - Thioether - Hemithioaminal - Carboximidamide - Propargyl-type 1,3-dipolar organic compound - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Organopnictogen compound - Organic nitrogen compound - Organic salt - Organic sodium salt - Carbonyl group - Organic zwitterion - Organic oxide - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom.
• External Descriptors: organic sodium salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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Mécanismes d'action

Propriétés chimiques et physiques

• Solubilité: DMSO 97 mg/mL Water 97 mg/mL Ethanol 3 mg/mL
• Poids moléculaire: 483.500 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 483.119 Da
• Monoisotopic Mass: 483.119 Da
• Topological Polar Surface Area: 176.000 Ų
• Heavy Atom Count: 33
• Formal Charge: 0
• Complexity: 851.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3