bio-THZ1 - ≥98% , CAS No.1604811-14-4

CAS: 1604811-14-4 Cat. No.: B647017 Formule: C₅₂H₆₅ClN₁₂O₈S Poids moléculaire: 1053.67 PubChem CID: 139035075

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7 . THZ1 is a selective and potent covalent CDK7 inhibitor with an IC 50 of 3.2 nM

Form:Solid

IC50& Target:CDK7

Specifications

Spécifications et pureté

≥98%

Mécanismes biochimiques et physiologiques

bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7 . THZ1 is a selective and potent covalent CDK7 inhibitor with an IC 50 of 3.2 nM.

Conditions de stockage de stockage

Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥98%

Noms et identifiants

• Sourires canoniques: CN(CCCNC(=O)NCCOCCOCCOCCNC(=O)CCCCC1C2C(CS1)NC(=O)N2)CC=CC(=O)NC3=CC=C(C=C3)C(=O)NC4=CC=CC(=C4)NC5=NC=C(C(=N5)C6=CNC7=CC=CC=C76)Cl
• IUPAC Name: 4-[[(E)-4-[3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethylcarbamoylamino]propyl-methylamino]but-2-enoyl]amino]-N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide
• InChIKey: ARPCJVVFIKPHFA-SFDVBDGFSA-N
• INCHI: 1S/C52H65ClN12O8S/c1-65(24-8-20-55-51(69)56-22-26-72-28-30-73-29-27-71-25-21-54-45(66)14-5-4-13-44-48-43(34-74-44)62-52(70)64-48)23-7-15-46(67)59-36-18-16-35(17-19-36)49(68)60-37-9-6-10-38(31-37)61-50-58-33-41(53)47(63-50)40-32-57-42-12-3-2-11-39(40)42/h2-3,6-7,9-12,15-19,31-33,43-44,48,57H,4-5,8,13-14,20-30,34H2,1H3,(H,54,66)(H,59,67)(H,60,68)(H2,55,56,69)(H,58,61,63)(H2,62,64,70)/b15-7+/t43-,44-,48-/m0/s1
• PubChem CID: 139035075
• Poids moléculaire: 1053.67

Propriétés chimiques et physiques

• Solubilité: DMSO : 120 mg/mL (113.89 mM; Need ultrasonic)

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1604811-14-4, the molecular formula is C52H65ClN12O8S, and the molecular weight is 1053.67 g/mol. InChIKey ARPCJVVFIKPHFA-SFDVBDGFSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.