Bobcat339 hydrochloride - 10mM in DMSO , CAS No.2436747-44-1

CAS: 2436747-44-1 Cat. No.: B656698 Formule: C₁₆H₁₃Cl₂N₃O Poids moléculaire: 334.20 PubChem CID: 138319672

QUALITÉ & PURETÉ 10mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme , with the IC 50 s of 33 μM and 73 μM for TET1 and TET2 , respectively. Bobcat339 hydrochloride is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription

In Vitro

Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:TET1 33 μM (IC 50 ) TET2 73 μM (IC 50 )

Spécifications

Spécifications et pureté

10mM in DMSO

Mécanismes biochimiques et physiologiques

Bobcat339 hydrochloride is a potent and selective cytosine-based inhibitor of TET enzyme , with the IC 50 s of 33 μM and 73 μM for TET1 and TET2 , respectively. Bobcat339 hydrochloride is useful to the field of epigenetics and serves as a starting point f

Conditions de stockage de stockage

Desiccated,Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Type d'action

INHIBITOR

Noms et identifiants

PubChem CID

138319672

Poids moléculaire

334.20