GRADE & PURITYNative?Native grade — protein/biomolecule in its natural (non-recombinant, non-denatured) form. Use when native structure and activity are required.from Bovine plasma; Protein concentration (see COA)
Native, from Bovine plasma; Protein concentration (see COA) Native for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Vue d’ensemble
Purified from freshly collected bovine plasma using a combination of salt precipitations and column chromatography. This protein is a mixture of Factor V/Va and intermediate activation products as judged by 4–20% gradient gels. Bovine Factor Va functions as a cofactor with the serine protease Factor Xa in the activation of prothrombin. This protein may be used as a source of V/Va in the prothrombinase complex. All bovine raw material is sourced from U.S. cows ≤ 30 months of age.
Buffer Composition: 20 mM HEPES-HCl, 0.15 M NaCl, 50% glycerol, pH7.4.
Extinction Coefficient (1%): 9.6 / 17.4
Molecular Weight: 330,000; 94,000; 74,000; 71,000; 31,000 Da
Protein Concentration determined by BCA assay
The Bovine Factor V/Va is a mixture of Factor V/Va and intermediate activation products as judged by 4–20% gradient gels. Bovine Factor Va functions as a cofactor with the serine protease Factor Xa in the activation of prothrombin. This protein may be used as a source of Factor V/Va in the prothrombinase complex
Specifications
Product Name
Bovine Factor V/Va
Grade
Native
Spécifications et pureté
Native, from Bovine plasma; Protein concentration (see COA)
Mécanismes biochimiques et physiologiques
Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. Activity regulation: Inhibited by SERPINA5.
Post-translational: Thrombin activates fa
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