bpV(HOpic) - ≥95% , CAS No.722494-26-0

CAS: 722494-26-0 Cat. No.: B334661 Formule: C₆H₄K₂NO₈V Poids moléculaire: 347.24 Numéro CE: 806-224-2 PubChem CID: 54692867

QUALITÉ & PURETÉ ≥95%

Synonyms

Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V) | Bisperoxovanadium(HOpic) | (5-hydroxy-2-pyridinecarboxylato-κN1,κO2)oxodiperoxy-vanadate(2-), dipotassium

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Vue d’ensemble

bpV(HOpic) is a bisperoxo oxovanadate dipotassium salt coordinated to 5-hydroxypyridine-2-carboxylate. This vanadium compound has been shown to be a potent inhibitor of protein phosphotyrosine phosphatase (PTP) and PTEN, and has been described to act as an insulin mimetic. This compound has been shown to activate the insulin receptor kinase of hepatoma cells, stimulate lipogenesis in adipocytes, and to enhance PI3K/Akt signaling that could prevent ischemia-reperfusion (I/R) injury to the myocardium.

Spécifications

Synonymes

Dipotassium bisperoxo (5-hydroxypyridine-2-carboxyl) oxovanadate (V) | Bisperoxovanadium(HOpic) | (5-hydroxy-2-pyridinecarboxylato-κN1,κO2)oxodiperoxy-vanadate(2-), dipotassium

Spécifications et pureté

≥95%

Mécanismes biochimiques et physiologiques

bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN

Conditions de stockage de stockage

Protected from light,Store at -20°C

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥95%

Noms et identifiants

Isomères SMILES

C1=CC(=NC=C1[O-])C(=O)O.OO.OO.O=[V].[K+].[K+]

WGK Allemagne

3

PubChem CID

54692867

Poids moléculaire

347.24

Propriétés chimiques et physiques

• Solubilité: Soluble in cold water (easily), and DMSO. Note: This product is not stable in water. Starts decomposition immediately after solubilization. Rate of decomposition is slower in dry DMSO.
• Sensibilité: Light & Moisture sensitive

Foire aux questions

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 722494-26-0, the molecular formula is C6H4K2NO8V, and the molecular weight is 347.24 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.