Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
A conserver entre 2 et 8°C Ships Glace humide Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
La calycosine (cyclosine) est un composé actif naturel ayant une activité antioxydante et anti-inflammatoire.
La calycosine, un isoflavone phytoestrogène, peut être utilisée pour promouvoir et étudier ses mécanismes d'angiogenèse via l'interaction avec le récepteur des œstrogènes et la voie de signalisation de la protéine kinase activée par les mitogènes (MAPK). La calycosine peut être utilisée pour étudier sa fonction et son rôle dans la neuroprotection par la prévention des lésions de reperfusion. La calycosine peut être utilisée comme bloqueur des canaux calciques. La calycosine peut être utilisée pour étudier son rôle dans la protection des HUVEC contre l'infiltration des macrophages induite par les produits finaux de glycation avancée.
| Pubchem Sid | 504763301 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504763301 |
| Sourires canoniques | COC1=C(C=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O |
| IUPAC Name | 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one |
| InChIKey | ZZAJQOPSWWVMBI-UHFFFAOYSA-N |
| INCHI | 1S/C16H12O5/c1-20-14-5-2-9(6-13(14)18)12-8-21-15-7-10(17)3-4-11(15)16(12)19/h2-8,17-18H,1H3 |
| Isomères SMILES | COC1=C(C=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O |
| WGK Allemagne | 3 |
| Poids moléculaire | 284.26 |
| Reaxy-Rn | 1292488 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1292488&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Classe | Isoflavonoids |
| Subclass | O-methylated isoflavonoids |
| Intermediate Tree Nodes | 4'-O-methylated isoflavonoids |
| Direct Parent | 3'-hydroxy,4'-methoxyisoflavonoids |
| Alternative Parents | 4'-O-methylisoflavones Hydroxyisoflavonoids Isoflavones Chromones Methoxyphenols Anisoles Phenoxy compounds Methoxybenzenes 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Alkyl aryl ethers Pyranones and derivatives Heteroaromatic compounds Oxacyclic compounds Hydrocarbon derivatives Organic oxides |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | 4p-o-methylisoflavone - 3'-hydroxy,4'-methoxyisoflavonoid - Isoflavone - Hydroxyisoflavonoid - Chromone - Methoxyphenol - 1-benzopyran - Benzopyran - Phenoxy compound - Phenol ether - Anisole - Methoxybenzene - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Pyranone - Phenol - Pyran - Monocyclic benzene moiety - Benzenoid - Heteroaromatic compound - Ether - Organoheterocyclic compound - Oxacycle - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as 3'-hydroxy,4'-methoxyisoflavonoids. These are isoflavonoids carrying a methoxy group attached to the C4' atom, as well as a hydroxyl group at the C3'-position of the isoflavonoid backbone. |
| External Descriptors | an isoflavone |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Article |
|---|---|---|---|
| Certificate of Analysis | Apr 15, 2026 | C123665 | |
| Certificate of Analysis | Apr 15, 2026 | C123665 | |
| Certificate of Analysis | Apr 15, 2026 | C123665 | |
| Certificate of Analysis | Apr 15, 2026 | C123665 | |
| Certificate of Analysis | May 23, 2025 | C123665 | |
| Certificate of Analysis | May 23, 2025 | C123665 | |
| Certificate of Analysis | May 23, 2025 | C123665 | |
| Certificate of Analysis | May 23, 2025 | C123665 | |
| Certificate of Analysis | May 23, 2025 | C123665 | |
| Certificate of Analysis | Apr 07, 2024 | C123665 | |
| Certificate of Analysis | Jul 03, 2023 | C123665 | |
| Certificate of Analysis | Sep 09, 2022 | C123665 |
| Poids moléculaire | 284.260 g/mol |
|---|---|
| XLogP3 | 2.400 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 284.068 Da |
| Monoisotopic Mass | 284.068 Da |
| Topological Polar Surface Area | 76.000 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 432.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Lei He, Qian Hu, Liyang Wei, Xuliyang Ge, Ning Yu, Ying Chen. (2023) Unravelling dynamic changes in non-volatile and volatile metabolites of pulses during soaking: An integrated metabolomics approach. FOOD CHEMISTRY, [PMID:37141754] [10.1016/j.foodchem.2023.136231] |
| 2. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] [10.1039/D1FO03816H] |
| 3. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:32480277] [10.1016/j.saa.2020.118519] |
| 4. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, [PMID:32330646] [10.1016/j.foodchem.2020.126807] |
| 5. Wang Liwei, Zhang Lu, Yun Yang, Liang Tingting, Yan Chaoqun, Mao Zhuoya, Zhang Jingfang, Liu Baoshe, Zhang Jian, Liang Taigang. (2024) Protective effect of astragaloside IV against zinc oxide nanoparticles induced human neuroblastoma SH-SY5Y cell death: a focus on mitochondrial quality control. MOLECULAR AND CELLULAR BIOCHEMISTRY, [PMID:39630360] [10.1007/s11010-024-05172-0] |
| 6. Haolin Zhang, Jingjing Zhang, Hui Cao, Petra Högger, Randolph Arroo, Mohamed A. Farag, Avi Shpigelman, Jianbo Xiao, Chunlin Li. (2025) Amination of Flavonoids Possessing a Pyrogallol Group in Cell Culture Medium at 37°C. Food Frontiers, 6 (2): (1058-1078). [PMID:] [10.1002/fft2.70002] |
| 7. Heng Wang, Zhaofei Liu, Xiangjun Xu, Haitao Zhang, Lei He, Ming Li. (2025) Calycosin Protects Against Chronic Prostatitis via Regulating Cellular Pyroptosis. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 93 (5): (e70084). [PMID:40349356] [10.1111/aji.70084] |
| 8. Yixuan Guo, Wenqian Liu, Bingsen Qi, Ziyi Liu, Jiaxin Wang, Le Yang, Jingcun Sun, Jinlong Qi. (2025) Integrating network pharmacology, molecular docking and experimental verification to explore the protective effect of Buyang Huanwu Decoction on cerebral ischemic stroke. Results in Chemistry, [PMID:] [10.1016/j.rechem.2025.102856] |
| 9. Xueying Zhang, Wei Lai, Mengdi Guo. (2026) A 3D MXene–CNT–Ag SERS platform with high enhancement and uniformity for quantitative analysis of complex botanical extracts. Surfaces and Interfaces, [PMID:] [10.1016/j.surfin.2026.110359] |
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