Cibles des maladies métaboliques
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196 produits
Produits populaires
- Hydroxocobalamin monohydrochlorideCAS: 58288-50-9 Numéro CE: 261-200-3 PubChem CID: 46783759 Formule: C62H89CoN13O15P · HCl Poids moléculaire: 1382.82Solid ≥98%◐ .Sur commande · 8–12 semaines Article #: H304094Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
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- SMILES
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- InChIKey
- KEHNCSYXYMMUCO-UHFFFAOYSA-K
- InChI
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- Synonymes
- cobalt(3+);[5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] 1-[3-[(4Z,9Z,14Z)-2,13,18-tris(...
- Recombinant Mouse Leptin ProteinCAS: 181030-10-4 Formule: NALyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: L329647Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Espèces
- Souris
- Accession #
- Q544U0
- Système d'expression
- E. coli
- Journée protéinée
- No tag
- Concentration d'endotoxine
- <1.0 EU/μg
- Bioactivité
- Immobilized Recombinant Mouse LEPR (C-10His) at 5μg/ml (100 μl/well) can bind Recombinant Mouse Leptin Biotinylated by NHS-biotin prior to testing.The ED50 of Recombinant Mouse Leptin is 1.16 ng/ml. Loaded Recombinant Mouse LEPR (C-10His) on HIS1K Biosensor, can bind Recombinant Mouse Leptin with an affinity constant of 0.196 nM as determined in BLI assay.
- Synonymes
- FLJ94114 | LEP | leptin (murine obesity homolog) | leptin (obesity homolog, mouse) | Leptin | OB | Obese protein | ob...
- LinderaneCAS: 13476-25-0 Formule: C15H16O4 Poids moléculaire: 260.285Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: L115734Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (1S,4E,12S,13S)-5,10-dimethyl-8,14,16-trioxatetracyclo[10.2.2.01,13.07,11]hexadeca-4,7(11),9-trien-15-one
- SMILES
- CC1=CCCC23C(O2)C(C4=C(C1)OC=C4C)OC3=O
- InChIKey
- KBMSVODXFLAQNJ-DXGHHDSJSA-N
- InChI
- 1S/C15H16O4/c1-8-4-3-5-15-13(19-15)12(18-14(15)16)11-9(2)7-17-10(11)6-8/h4,7,12-13H,3,5-6H2,1-2H3/b8-4+/t12-,13-,15-/m0/s1
- Recombinant Mouse TNF-alpha ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥97%(SDS-PAGE&HPLC)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: rp154759Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Espèces
- Souris
- Accession #
- P06804
- Système d'expression
- E. coli
- Journée protéinée
- No tag
- Concentration d'endotoxine
- <0.01 EU/μg
- Bioactivité
- Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.1 ng/mL.
- Synonymes
- Recombinant Murine Tumor Necrosis Factor alpha (rMuTNF-α) | APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, mo...
- Recombinant Human TNF-alpha ProteinLiquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥95%(SDS-PAGE) See COA● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: rp152506Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Espèces
- Humain
- Accession #
- P01375
- Système d'expression
- E. coli
- Journée protéinée
- No tag
- Concentration d'endotoxine
- <0.1 EU/μg
- Bioactivité
- Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.05 ng/mL.
- Synonymes
- APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alpha | TNF-a...
- Recombinant Human IL-2 ProteinLyophilized Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: rp147476Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Espèces
- Humain
- Accession #
- P60568
- Système d'expression
- CHO-K1
- Journée protéinée
- His
- Concentration d'endotoxine
- <1.0 EU/μg
- Bioactivité
- 1、Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is typically less than 2.5 ng/mL. 2、Measured in a cell proliferation assay using mouse splenocytes. The ED50 for this effect is typically less than 30.0 ng/mL.
- Synonymes
- IL-2 | T-cell growth factor | TCGF
- Recombinant Human Leptin ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥97%(SDS-PAGE&HPLC)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: rp148245Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Espèces
- Humain
- Accession #
- P41159
- Système d'expression
- E. coli
- Journée protéinée
- No tag
- Concentration d'endotoxine
- <1.0 EU/μg
- Bioactivité
- Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human Leptin R transfected BaF3 murine proB cells is less than 2 ng/ml, corresponding to a specific activity of > 5.0 × 105 IU/mg.
- Synonymes
- FLJ94114 | LEP | Leptin (murine obesity homolog) | Leptin (obesity homolog, mouse) | Leptin | OB | Obese protein | ob...
- Recombinant Rat TNF-alpha ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: rp155241Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Espèces
- conseil
- Accession #
- P16599
- Système d'expression
- HEK293
- Journée protéinée
- C-His
- Concentration d'endotoxine
- <0.1 EU/μg
- Bioactivité
- Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The EC50 for this effect is typically <5 pg/mL.
- Synonymes
- APC1 protein | Cachectin | Cachetin | RATTNF | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alph...
- Recombinant Human Osteoprotegerin ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: rp149600Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Espèces
- Humain
- Accession #
- O00300
- Système d'expression
- E. coli
- Journée protéinée
- No tag
- Concentration d'endotoxine
- <1.0 EU/μg
- Bioactivité
- Fully biologically active when compared to standard. The ED50 as determined by neutralizing the stimulation of U937 cells is less than 10 ng/ml in the presence of 10 ng/mL soluble rHuRANKL (sRANKL).
- Synonymes
- OCIF | OCIFMGC29565 | OPG | OPGtumor necrosis factor receptor superfamily member 11B | Osteoclastogenesis inhibitory ...
- Recombinant Human IL-2 Receptor Alpha ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥97%(SDS-PAGE)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: rp147480Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Espèces
- Humain
- Accession #
- P01589
- Système d'expression
- HEK293
- Journée protéinée
- C-His
- Concentration d'endotoxine
- <1.0 EU/μg
- Bioactivité
- 1. Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.2 ‑1.2 µg/mL in the presence of 30 ng/mL of recombinant human IL-2. 2. Immobilized Recombinant Human IL-2 Protein (rp156004) at 1 μg/mL can bind biotinylated Recombinant Human IL-2 Receptor Alpha Protein (rp147480).
- Synonymes
- Interleukin 2 receptor alpha chain | CD25 | CD25 antigen | IDDM10 | IL 2 receptor alpha subunit | IL-2 receptor subun...
- Recombinant Human IL-6R ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥90%(SDS-PAGE)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: rp147628Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Espèces
- Humain
- Accession #
- P08887
- Système d'expression
- HEK293
- Journée protéinée
- C-His
- Concentration d'endotoxine
- <1.0 EU/μg
- Bioactivité
- 1. Immobilized Recombinant Human IL-6 Protein at 2 μg/mL can bind Recombinant Human IL-6R Protein (rp147628) the EC50 is 8.0 - 24.0 ng/mL. 2. Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10.0 - 60.0 ng/mL.3. Using the Octet RED System, the affinity constant (Kd) of Recombinant Human IL-6R Protein (rp147628) bound Anti-IL6R Antibody was 0.1 nM.
- Synonymes
- CD126 | gp80 | IL-6 R alpha | IL6Q | IL6R alpha | IL-6R alpha | IL6R | IL-6R-1 | IL6RA | IL-6Ra | IL6RQ | interleukin...
- Recombinant Mouse IL-2 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥98%(SDS-PAGE)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: rp154174Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Espèces
- Souris
- Accession #
- P04351
- Système d'expression
- HEK293
- Journée protéinée
- N-His
- Concentration d'endotoxine
- <1.0 EU/μg
- Bioactivité
- Recombinant Mouse IL-2 stimulates cell proliferation of the CTLL-2 mouse cytotoxic T cell line. The ED50 for this effect is typically less than 2.5 ng/mL.
- Synonymes
- Aldesleukin | IL2 | IL-2 | IL-2lymphokine | interleukin 2 | interleukin-2 | involved in regulation of T-cell clonal e...
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Foire aux questions
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Work backwards from the target structure: identify the bonds you need to form, then pick the Metabolic Disease Targets entry whose functional groups, protecting-group pattern, and stereochemistry match. Compare purity, available pack sizes, and stability under your reaction conditions before committing to a route.
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