Cevimeline hydrochloride , CAS No.153504-70-2

CAS: 153504-70-2 Cat. No.: C275672 Formule: C₁₀H₁₇NOS·HCl·1/2H₂O Poids moléculaire: 199.31 (anhydrous free base ba Numéro CE: 642-988-1 PubChem CID: 71307519

Synonyms

(+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine] | 2-METHYL-1'-AZASPIRO[[1,3]OXATHIOLANE-5,3'-BICYCLO[2.2.2]OCTANE] (HCL) | Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-,hydrochloride | AF-102B | Cevimeline Hydrochloride Sal

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Vue d’ensemble

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Synonymes

(+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine] | 2-METHYL-1'-AZASPIRO[[1,3]OXATHIOLANE-5,3'-BICYCLO[2.2.2]OCTANE] (HCL) | Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-,hydrochloride | AF-102B | Cevimeline Hydrochloride Sal

Mécanismes biochimiques et physiologiques

Selective M 1 and M 3 receptor agonist. Induces atropine-sensitive contractions of ilea and trachea (EC 50 values are 3.5 and 3 μM, respectively). Reverses AF64A-induced cognitive impairments and promotes saliva secretion in vivo.

Conditions de stockage de stockage

Store at -20°C,Desiccated

Expédié en

Ice chest + Ice pads

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Noms et identifiants

• Sourires canoniques: CC1OC2(CN3CCC2CC3)CS1.CC1OC2(CN3CCC2CC3)CS1.O.Cl.Cl
• IUPAC Name: (5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane];hydrate;dihydrochloride
• InChIKey: ZSTLCHCDLIUXJE-MMPAUJBDSA-N
• INCHI: 1S/2C10H17NOS.2ClH.H2O/c2*1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11;;;/h2*8-9H,2-7H2,1H3;2*1H;1H2/t2*8?,10-;;;/m11.../s1
• Isomères SMILES: CC1O[C@]2(CN3CCC2CC3)CS1.CC1O[C@]2(CN3CCC2CC3)CS1.O.Cl.Cl
• WGK Allemagne: 3
• PubChem CID: 71307519
• Poids moléculaire: 199.31 (anhydrous free base ba

Propriétés chimiques et physiques

• Solubilité: Chloroform (slighty), Methanol (slightly)