Chiralyst Rh639 - ≥99.95% metals basis , CAS No.223392-99-2

CAS: 223392-99-2 Cat. No.: C294378 Formule: C₃₁H₃₆N₂ClO₂SRh Poids moléculaire: 639.06 Numéro CE: 812-286-1 PubChem CID: 131637300

GRADE & PURITY ≥99.95% metals basis

Synonyms

223392-99-2|[(1R,2R)-2-Amino-1,2-diphenylethyl]-(4-methylphenyl)sulfonylazanide;methane;1,2,3,4,5-pentamethylcyclopentane;rhodium(2+);chloride|[N-[(1R,2R)-2-(amino-kappaN)-1,2-diphenylethyl]-4-methylbenzenesulfonamidato-kappaN]chloro[(1,2,3,4,5-eta)-1,2

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Vue d’ensemble

Product class
M-N, Homogeneous Catalysts, M-C, Arene/Aryl Ligands, Chiral Ligands

Reaction type
Hydrogenation, Asymmetric Reactions, Asymmetric Hydrogenation, Transfer Hydrogenation

Chemical properties

Chemical formula

C31H36N2ClO2SRh

Empirical formula

Rh[(R,R)-TsDPEN](C5Me5)Cl

Molecular weight

639.06

Metal

Rh

Theoretical metal content

16

Physical state

crystalline

Color

orange brown

Metal purity

99.95

Applications & references

Asymmetric reduction of α-sulfonyloxy acetophenone compound yielding an optically active 2-sulfonyloxy-1-phenylethanol derivative with high enantiomer excess.

Reference: WO2008 054155

Asymmetric synthesis of ß-amino alcohols by rhodium catalyzed transfer hydrogenation of α-keto imines.

Reference: Tetrah. Asym. 2010, 21, 2244 (DOI: 10.1016/j.tetasy.2010.07.004)

One pot synthesis of sterically active epoxides starting from α-chloroacetophenones including a asymmetric transfer hydrogenation step.

Reference: Tetrah.  2004, 60, 7411 (DOI: 10.1016/j.tet.2004.06.076)

Synthesis of optically active styrene oxides by asymmetric reduction of 2-chloroacetophenones.

Reference: Org. Lett. 2002, 4, 4373 (DOI: 10.1021/ol020213o)

Enantioselective preparation of cyclic sulfamidates by using asymmetric transfer hydrogenation.

Reference: Org. Lett. 2010, 12, 4184 (DOI: 10.1021/ol1017905)

Asymmetric transfer hydrogenation of α-aminoalkyl α’-chloromethylketones yielding useful intermediates for the total synthesis of inhibitors of HIV protease and ß-secretase in Alzheimer disease.

Reference: J. Org. Chem. 2004, 69, 7391 (DOI: 10.1021/jo0491455)

Specifications

Synonymes

223392-99-2 | [(1R,2R)-2-Amino-1,2-diphenylethyl]-(4-methylphenyl)sulfonylazanide;methane;1,2,3,4,5-pentamethylcyclopentane;rhodium(2+);chloride | [N-[(1R,2R)-2-(amino-kappaN)-1,2-diphenylethyl]-4-methylbenzenesulfonamidato-kappaN]chloro[(1,2,3,4,5-eta)-1,2

Spécifications et pureté

≥99.95% metals basis

Conditions de stockage de stockage

Store at 2-8°C,Argon charged

Expédié en

Wet ice

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Pureté

≥99.95% metals basis

Noms et identifiants

• Sourires canoniques: C.CC1C(C(C(C1C)C)C)C.CC1=CC=C(C=C1)S(=O)(=O)[N-]C(C2=CC=CC=C2)C(C3=CC=CC=C3)N.[Cl-].[Rh+2]
• IUPAC Name: [(1R,2R)-2-amino-1,2-diphenylethyl]-(4-methylphenyl)sulfonylazanide;methane;1,2,3,4,5-pentamethylcyclopentane;rhodium(2+);chloride
• InChIKey: YLCLYZZZTCWCEJ-ZPVXIRCVSA-M
• INCHI: 1S/C21H21N2O2S.C10H20.CH4.ClH.Rh/c1-16-12-14-19(15-13-16)26(24,25)23-21(18-10-6-3-7-11-18)20(22)17-8-4-2-5-9-17;1-6-7(2)9(4)10(5)8(6)3;;;/h2-15,20-21H,22H2,1H3;6-10H,1-5H3;1H4;1H;/q-1;;;;+2/p-1/t20-,21-;;;;/m1..../s1
• Isomères SMILES: C.CC1C(C(C(C1C)C)C)C.CC1=CC=C(C=C1)S(=O)(=O)[N-][C@H](C2=CC=CC=C2)[C@@H](C3=CC=CC=C3)N.[Cl-].[Rh+2]
• PubChem CID: 131637300
• Poids moléculaire: 639.06

Foire aux questions

What does the trace-metals specification mean?

This product is specified at ≥99.95% on a trace-metals basis. That figure describes metallic impurity content rather than overall chemical assay, so it is the relevant specification for ICP-MS, semiconductor and battery applications. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 223392-99-2, the molecular formula is C31H36N2ClO2SRh, and the molecular weight is 639.06 g/mol. InChIKey YLCLYZZZTCWCEJ-ZPVXIRCVSA-M.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.