Chlorhydrate de tariquidar - ≥98% , CAS No.1992047-62-7

CAS: 1992047-62-7 Cat. No.: T287716 Formule: C₃₈H₃₈N₄O₆.2HCl Poids moléculaire: 719.66 PubChem CID: 121513890

GRADE & PURITY ≥98%

Synonyms

N-[2-[[4-[2-(3,4-dihydro-6,7-diméthoxy-2(1H)-isoquinolinyl)éthyl]phényl]amino]carbonyl]-4,5-diméthoxyphényl]-3-quinoléinecarbxamide dihydrochloride

Storage

Conserver à -20°C

Shipped In

Glacière + blocs de glace

Specifications

Synonymes

N-[2-[[4-[2-(3,4-dihydro-6,7-diméthoxy-2(1H)-isoquinolinyl)éthyl]phényl]amino]carbonyl]-4,5-diméthoxyphényl]-3-quinoléinecarbxamide dihydrochloride

Spécifications et pureté

≥98%

Mécanismes biochimiques et physiologiques

Puissant inhibiteur de la glycoprotéine P (P-gp) (IC50= 5,1 nM). Inverse la résistance aux médicaments dans de multiples lignées cellulaires MDR. Agit comme substrat de la protéine de résistance au cancer du sein (BCRP) à de faibles concentrations et agit

Conditions de stockage de stockage

Conserver à -20°C

Expédié en

Glacière + blocs de glace

Pureté

≥98%

Noms et identifiants

Pubchem Sid

504772957

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504772957

Sourires canoniques

COC1=C(C=C2CN(CCC2=C1)CCC3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4NC(=O)C5=CC6=CC=CC=C6N=C5)OC)OC)OC.Cl.Cl

IUPAC Name

N-[2-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide;dihydrochloride

InChIKey

ZJCJRGRTDKIFJJ-UHFFFAOYSA-N

INCHI

1S/C38H38N4O6.2ClH/c1-45-33-18-25-14-16-42(23-28(25)19-34(33)46-2)15-13-24-9-11-29(12-10-24)40-38(44)30-20-35(47-3)36(48-4)21-32(30)41-37(43)27-17-26-7-5-6-8-31(26)39-22-27;;/h5-12,17-22H,13-16,23H2,1-4H3,(H,40,44)(H,41,43);2*1H

PubChem CID

121513890

Poids moléculaire

719.66

Propriétés chimiques et physiques

• Solubilité: Solvent:DMSO, Max Conc. mg/mL: 71.97, Max Conc. mM: 100

Foire aux questions

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1992047-62-7, the molecular formula is C38H38N4O6.2HCl, and the molecular weight is 719.66 g/mol. InChIKey ZJCJRGRTDKIFJJ-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.